Paid Clinical Trials in Birmingham, AL

As of June 2026, 1,065 paid clinical trials are recruiting in Birmingham, Alabama. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,065 clinical trials

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MIST (Metabolic Intervention With Semaglutide and THR-β Therapy) Trial

for Adult Obesity

Drug: Semaglutide

15 locations incl. Birmingham

Sponsor: Eccogene

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07505303·Phase 2·Not Yet Recruiting

Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis

for Knee Cartilage Defects

17 locations incl. Birmingham

Sponsor: Medipost, Inc.

Sex: All·Age: 18 - 75

Code: NCT07339111·Phase 3·Recruiting

Apply to this trial

A Phase IIb Dose-ranging Study to Assess the Efficacy and Safety of GIA632 in Participants With Non-segmental Vitiligo

for Non-segmental Vitiligo

Drug: GIA632

18 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 99

Code: NCT07431177·Phase 2·Recruiting

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To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.

for Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT07191262·Recruiting

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Ambulatory Blood Pressure Monitoring (ABPM) Study in Hypogonadal Men

for Hypogonadism, Male

6 locations incl. Birmingham

Sponsor: Azurity Pharmaceuticals

Sex: Male·Age: 18 - 75

Code: NCT07328542·Phase 4·Not Yet Recruiting

A Study to Assess the Effectiveness and Safety of IPN10200 in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows

for Moderate to Severe Glabellar Lines

17 locations incl. Birmingham

Sponsor: Ipsen

Sex: All·Age: 18 - 80

Code: NCT07427797·Phase 3·Recruiting

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Ublituximab in Autoantibody Positive Immune Mediated Necrotizing Myopathy

for Autoimmune Disorders

8 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT07103746·Phase 2·Recruiting

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Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD

for COPD

10 locations incl. Birmingham

Sponsor: Nuvaira, Inc.

Sex: All·Age: 40 - 80

Code: NCT07051707·Recruiting

Apply to this trial

Brain Uptrain to Improve Learning and Development

for Term Infant

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 1 Day - 7 Days

Code: NCT06638801·Recruiting

Apply to this trial

Early Time-Restricted Eating in Older Adults With Hypertension

for Hypertension

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 60+

Code: NCT07135505·Recruiting

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A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain

for Diabetic Peripheral Neuropathic Pain

Drug: LY4065967

36 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07285018·Phase 2·Recruiting

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A Study of Patients With Fabry Disease (US Specific)

for Fabry Disease

8 locations incl. Birmingham

Sponsor: Amicus Therapeutics

Sex: All·Age: 18+

Code: NCT06906367·Recruiting

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A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy

for Symptomatic Genetic Dilated Cardiomyopathy

18 locations incl. Birmingham

Sponsor: Kardigan, Inc.

Sex: All·Age: 18+

Code: NCT07210723·Phase 2, Phase 3·Recruiting

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Phase 2 EL219 Versus Liposomal Amphotericin B or Voriconazole for Early Antifungal Therapy

for Invasive Mould Infection

5 locations incl. Birmingham

Sponsor: Elion Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07215273·Phase 2·Recruiting

Apply to this trial

Trial of Reducing Inpatient Antibiotic Durations in Children

for Pneumonia

10 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 60 Days - 17

Code: NCT07322146·Phase 4·Enrolling By Invitation

Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

for Chronic Obstructive Pulmonary Disease (COPD)

Drug: Omalizumab

23 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 40+

Code: NCT07059091·Phase 2·Recruiting

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A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

for Overweight

Drug: Eloralintide

54 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07392190·Phase 3·Recruiting

Apply to this trial

PrOTECT AL: PrEP Optimization Through Enhanced Continuum Tracking

for HIV

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT07231640·Recruiting

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Study of BMS-986453 in Newly Diagnosed Multiple Myeloma

for Multiple Myeloma

1 location in Birmingham

Sponsor: Susan Bal

Sex: All·Age: 19+

Code: NCT07333261·Phase 1·Recruiting

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A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout

for Uncontrolled Gout

48 locations incl. Birmingham

Sponsor: Amgen

Sex: All·Age: 18+

Code: NCT07388498·Phase 3·Recruiting

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A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

29 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07266441·Phase 2·Recruiting

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A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus

for Type II Diabetes Mellitus

31 locations incl. Birmingham

Sponsor: Corxel Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT07340320·Phase 2·Recruiting

Apply to this trial

Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes

for Metastatic Ewing Sarcoma

17 locations incl. Birmingham

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 1+

Code: NCT07194044·Phase 1·Recruiting

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A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia

for Dystonia

37 locations incl. Birmingham

Sponsor: Vima Therapeutics

Sex: All·Age: 18 - 65

Code: NCT07304089·Phase 2·Recruiting

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A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

11 locations incl. Birmingham

Sponsor: Rein Therapeutics

Sex: All·Age: 40+

Code: NCT06968845·Phase 2·Recruiting

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Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa (HS)

Drug: Povorcitinib

25 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 12 - 17

Code: NCT07213973·Phase 2·Recruiting

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Early Life Exposures Among Children With Sickle Cell Disease

for Sickle Cell Disease

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18 - 50

Code: NCT05377372·Recruiting

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Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury

for Acute Kidney Injury

3 locations incl. Birmingham

Sponsor: Hope Biosciences LLC

Sex: All·Age: 18 - 75

Code: NCT06654193·Phase 1, Phase 2·Recruiting

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Investigating the Utility of Augmented Reality Assistance for Ultrasound-Guided Vascular Access

for Vascular Access

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 5+

Code: NCT07208071·Recruiting

Apply to this trial

HIV, Equity, and Addiction Training (HEAT) Program

for Substance Use Disorders

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT06370481·Recruiting

Apply to this trial

Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)

for Hepatitis

Drug: Larsucosterol

48 locations incl. Birmingham

Sponsor: Bausch Health Americas, Inc.

Sex: All·Age: 18+

Code: NCT07428538·Phase 3·Recruiting

Apply to this trial

A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement

for Intrahepatic Cholangiocarcinoma

Drug: Durvalumab

2 locations incl. Birmingham

Sponsor: Mehmet Akce

Sex: All·Age: 18+

Code: NCT06728410·Phase 2·Recruiting

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Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for Advanced Endometrial Carcinoma

Drug: Bevacizumab

211 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07198074·Phase 3·Recruiting

Apply to this trial

A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma

for Squamous Cell Carcinoma of Head and Neck

8 locations incl. Birmingham

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 18 - 74

Code: NCT07219212·Phase 1·Recruiting

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The Use of Near-Infrared Fluorescence Cholangiography With Indocyanine Green (ICG) in the Work Up of Neonatal Cholestasis

for Biliary Atresia

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 2 Weeks - 4 Months·Accepts healthy volunteers

Code: NCT07250854·EARLY_Phase 1·Recruiting

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Digoxin Medulloblastoma Study

for Medulloblastoma

15 locations incl. Birmingham

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 12 Months - 30

Code: NCT06701812·Phase 2·Recruiting

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A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)

for Chronic Inducible Urticaria

26 locations incl. Birmingham

Sponsor: Celldex Therapeutics

Sex: All·Age: 18+

Code: NCT07266402·Phase 3·Recruiting

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TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

for Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

Drug: Tulmimetostat

8 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT07190300·Phase 1, Phase 2·Recruiting

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A Study of Buntanetap in Participants With PD

for Parkinson's Disease (PD)

27 locations incl. Birmingham

Sponsor: Annovis Bio Inc.

Sex: All·Age: 40 - 85

Code: NCT07284784·Phase 2, Phase 3·Recruiting

Apply to this trial

ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults

for Asthma

14 locations incl. Birmingham

Sponsor: Enveda Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07301255·Phase 2·Recruiting

Apply to this trial