Paid Clinical Trials in Birmingham, AL

As of June 2026, 1,065 paid clinical trials are recruiting in Birmingham, Alabama. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,065 clinical trials

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AMPLIFI: Adaptive Modulation of Plasticity Through Lactate and Fitness Interventions

for Stroke, Chronic

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT06950060·Not Yet Recruiting

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

for Atypical Teratoid/Rhabdoid Tumor

10 locations incl. Birmingham

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 21

Code: NCT06465199·Phase 1, Phase 2·Recruiting

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Study of INCA036978 in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

Drug: INCA036978

22 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07441694·Phase 1·Recruiting

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A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

for Obesity

Drug: NNC0487-0111

202 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07567001·Phase 3·Not Yet Recruiting

Use of Tinted Contact Lenses for Concussion-Related Light Sensitivity

for Concussion, Mild

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT07223086·Recruiting

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Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

for Myopia

14 locations incl. Birmingham

Sponsor: Ohio State University

Sex: All·Age: 6 - 11·Accepts healthy volunteers

Code: NCT07567040·Phase 3·Recruiting

Apply to this trial

Video Inspired Discussions About Ethical Outcomes in Pediatrics

for Pediatric Cancer

4 locations incl. Birmingham

Sponsor: Massachusetts General Hospital

Sex: All·Age: All ages

Code: NCT06786104·Recruiting

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A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

for Alpha 1 Antitrypsin Deficiency

10 locations incl. Birmingham

Sponsor: Grifols Therapeutics LLC

Sex: All·Age: 18 - 80

Code: NCT07555483·Phase 3·Recruiting

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Boosting Olfactory and Sensory Training Study (BOOST)

for HIV (Human Immunodeficiency Virus)

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 40+

Code: NCT07221123·Phase 2·Recruiting

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Folic Acid Salt Study (FISFA Zambia)

for Folate Deficiency

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06734611·Not Yet Recruiting

Pycnogenol (French Maritime Pine Bark) for the Treatment of Gulf War Illness

for Gulf War Syndrome

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: Male·Age: 18+

Code: NCT07266571·Not Yet Recruiting

A 52-Week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream in Adult Participants With Lichen Sclerosus

for Lichen Sclerosus

5 locations incl. Birmingham

Sponsor: LEO Pharma

Sex: All·Age: 18+

Code: NCT07335588·Phase 3·Recruiting

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Understanding the Impact of Meal Timing on Neurological Health in Adults With Multiple Sclerosis

for Multiple Sclerosis

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 64

Code: NCT07475377·Not Yet Recruiting

Occlutech AFR Fontan Study

for Failure of Fontan Type Circulation

7 locations incl. Birmingham

Sponsor: Occlutech International AB

Sex: All·Age: All ages

Code: NCT07532369·Not Yet Recruiting

Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants

for Bronchopulmonary Dysplasia

2 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 1 Month - 5 Months·Accepts healthy volunteers

Code: NCT06373289·Recruiting

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Pivotal Trial to Evaluate the Safety and Effectiveness of the P&F TricValve® Transcatheter Bicaval Valve System

for Tricuspid Valve Disease

35 locations incl. Birmingham

Sponsor: P+F Products + Features USA Inc.

Sex: All·Age: 18 - 85

Code: NCT06458907·Not Yet Recruiting

DOC1021 Dendritic Cell Immunotherapy for Refractory Melanoma

for Refractory Melanoma

2 locations incl. Birmingham

Sponsor: Diakonos Oncology Corporation

Sex: All·Age: 18+

Code: NCT07288112·Phase 1, Phase 2·Recruiting

Apply to this trial

Evaluating an Interactive Digital Toolkit for Women's PrEP Implementation

for HIV Prevention

4 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07292584·Not Yet Recruiting

Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy

for Type 2 Diabetes

16 locations incl. Birmingham

Sponsor: Biomea Fusion Inc.

Sex: All·Age: 18 - 70

Code: NCT07502508·Phase 2·Recruiting

Apply to this trial

Empowering Faith-based Communities to Provide Personalized Diabetes Self-management Education and Support (DSMES) in the Magic City

for Blood Cholesterol

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07556354·Not Yet Recruiting

A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV

for MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease

10 locations incl. Birmingham

Sponsor: Naga P. Chalasani

Sex: All·Age: 18+

Code: NCT07143968·Phase 2·Recruiting

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Cocoa to Maximize Exercise Training in Older Adults - The COMET Trial

for Mobility Disability

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 55+

Code: NCT07161726·Phase 1, Phase 2·Recruiting

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Effects of Oral Tranexamic Acid on Short Term Postoperative Outcomes Following Total Shoulder Arthroplasty

for Shoulder Arthroplasty

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 79

Code: NCT06902714·Phase 3·Recruiting

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Biweekly Long-term Occidiofungin Study for Suppression of Mycotic Recurrence

for Candidiasis, Vulvovaginal

1 location in Birmingham

Sponsor: Sano Chemicals Inc

Sex: Female·Age: 18 - 65

Code: NCT07521137·Phase 2·Not Yet Recruiting

Wearable Integration in Symptom Evaluation for Cancer Survivors

for Cancer

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT07463547·Enrolling By Invitation

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

for Diabetes Mellitus

Drug: NNC0487-0111

15 locations incl. Birmingham

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07533175·Phase 3·Recruiting

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Pharmacokinetic and Early Efficacy of OPT101 in Patients With Type 1 Diabetes Mellitus

for Type I Diabetes

5 locations incl. Birmingham

Sponsor: Op-T LLC

Sex: All·Age: 18 - 50

Code: NCT06964087·Phase 2·Recruiting

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Menopausal HT for Women Living With HIV (HoT)

for HIV Infection

23 locations incl. Birmingham

Sponsor: Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

Sex: Female·Age: 40 - 60

Code: NCT06856174·Phase 4·Recruiting

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A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

for Solid Tumors

Drug: INCB161734

68 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07522073·Phase 3·Recruiting

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Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)

for Atrial Fibrillation (AF)

22 locations incl. Birmingham

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18+

Code: NCT07298473·Recruiting

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Extensively Hydrolyzed Formula Growth Monitioring Study (GMS)

for Growth

12 locations incl. Birmingham

Sponsor: Mead Johnson Nutrition

Sex: All·Age: 10 Days - 14 Days·Accepts healthy volunteers

Code: NCT07513506·Not Yet Recruiting

Bowel Continence Across the Lifespan in People With Spina Bifida

for Spina Bifida

24 locations incl. Birmingham

Sponsor: David Chu

Sex: All·Age: 5+

Code: NCT07390318·Recruiting

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A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)

for Cytomegalovirus Prophylaxis

16 locations incl. Birmingham

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: Up to 17

Code: NCT07199465·Phase 1·Recruiting

Apply to this trial

Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets

for Type 2 Diabetes

16 locations incl. Birmingham

Sponsor: Biomea Fusion Inc.

Sex: All·Age: 18 - 70

Code: NCT07502495·Phase 2·Recruiting

Apply to this trial

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

for Breast Neoplasms

39 locations incl. Birmingham

Sponsor: Natera, Inc.

Sex: All·Age: 18+

Code: NCT07214532·Recruiting

Apply to this trial

Pilot Trial for WounDx™ Clinical Decision Support Tool

for Wounds

5 locations incl. Birmingham

Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine

Sex: All·Age: 18 - 65

Code: NCT06921707·Recruiting

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A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1

for HIV

8 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07390955·Phase 1·Recruiting

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Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis

for Plaque Psoriasis

22 locations incl. Birmingham

Sponsor: Oruka Therapeutics, Inc.

Sex: All·Age: 18 - 79

Code: NCT07474792·Phase 2·Recruiting

Apply to this trial

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

for Obesity or Overweight

Drug: Enicepatide

25 locations incl. Anniston

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07351045·Phase 3·Recruiting

Apply to this trial

VENTURI (VENTilation Using Respiratory Imaging)

for Asthma

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 75

Code: NCT07282886·Phase 2·Recruiting

Apply to this trial