Clinical Trials at Johns Hopkins University

As of June 2026, 189 paid clinical trials are recruiting at Johns Hopkins University, located at Brain Injury Outcomes at Johns Hopkins University, 750 E Pratt St, Baltimore, MD 21202, phone (410) 361-7999 in Baltimore, Maryland. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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189 clinical trials at Johns Hopkins University

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Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

for Heart Diseases

42 locations incl. Los Angeles

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18+

Code: NCT04124120·Recruiting

Apply to this trial

A Study to Follow Patients With Adult Growth Hormone Deficiency (AGHD) Treated With Sogroya® for Long Term Safety Information

for Adult Growth Hormone Deficiency

29 locations incl. Phoenix

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT05718570·Enrolling By Invitation

Liquid Biopsy-informed Precision Oncology Study to Evaluate Utility of Plasma Genomic Profiling for Therapy Selection

for Solid Tumor

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT05585684·Recruiting

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Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry

for Adult Congenital Heart Disease

3 locations incl. Baltimore

Sponsor: Leiden University Medical Center

Sex: All·Age: 18+

Code: NCT06932081·Recruiting

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A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma

for Mature B-Cell Non-Hodgkin Lymphoma

Drug: Glofitamab

10 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 6 Months - 30

Code: NCT05533775·Phase 1, Phase 2·Recruiting

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Longitudinal Early Advance Care Planning Discussions and Documentation (LEADD) Program: An Exploratory Study in Adolescents and Young Adults (AYAs) Receiving Hematopoietic Stem Cell Transplant

for Hematopoietic Stem Cell Transplantation

2 locations incl. Baltimore

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120·Accepts healthy volunteers

Code: NCT05605574·Recruiting

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Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

for Hematologic Malignancy

29 locations incl. Los Angeles

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 - 21

Code: NCT05476770·Phase 1·Recruiting

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KRAS-Targeted Vaccine With Chemoimmunotherapy, Nivolumab and Ipilimumab for Patients With NSCLC

for Non-Small Cell Lung Cancer

Drug: Ipilimumab

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18 - 100

Code: NCT05254184·Phase 1·Recruiting

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StableEyes With Active Neurofeedback

for Vestibular Disorder

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21 - 70·Accepts healthy volunteers

Code: NCT05622344·Recruiting

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Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

for Peripartum Cardiomyopathy, Postpartum

64 locations incl. Birmingham

Sponsor: Dennis M. McNamara, MD, MS

Sex: Female·Age: 18+

Code: NCT05180773·Phase 4·Recruiting

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TEMPUS Small Cell Lung Cancer OBSERVATIONAL STUDY (Sculptor)

for Small Cell Lung Cancer

11 locations incl. Los Alamitos

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT05257551·Recruiting

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GEMINI-NSCLC: NSCLC Biomarker Study

for Non-Small Cell Lung Cancer

58 locations incl. Birmingham

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT05236114·Recruiting

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Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

for Relapsed Adult AML

20 locations incl. Birmingham

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 120·Accepts healthy volunteers

Code: NCT05237258·Recruiting

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Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

for Non-small Cell Lung Cancer (NSCLC)

21 locations incl. Orange

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT05379985·Phase 1, Phase 2·Recruiting

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The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

for Arrythmia

19 locations incl. Phoenix

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05034432·Phase 4·Recruiting

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The CONFORM Pivotal Trial

for Atrial Fibrillation

76 locations incl. Birmingham

Sponsor: Conformal Medical, Inc

Sex: All·Age: 18+

Code: NCT05147792·Recruiting

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CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer

for HER2-negative Breast Cancer

7 locations incl. Chicago

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 99

Code: NCT05029999·Phase 1·Recruiting

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Use of a Patient-Centered Electronic App to Increase ED Patient's Knowledge on HCV to Improve the HCV Care Continuum

for Hepatitis C

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 100

Code: NCT04162938·Recruiting

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Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts

for Viral Infection

3 locations incl. Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 3 Months - 80

Code: NCT04691622·Phase 1·Recruiting

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Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations

for Metastatic Non Small Cell Lung Cancer

36 locations incl. Chandler

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT05215340·Phase 3·Recruiting

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Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

for Epiretinal Membrane

45 locations incl. Scottsdale

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 50+

Code: NCT05145491·Recruiting

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A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

for Crohn's Disease (CD)

22 locations incl. Phoenix

Sponsor: Takeda

Sex: All·Age: 2 - 17

Code: NCT04779320·Phase 3·Recruiting

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Study of 111In-XYIMSR-01 SPECT/CT in Patients With Metastatic Clear Cell Renal Cell

for Renal Cell Carcinoma (Kidney Cancer)

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT07062549·Phase 1·Recruiting

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Diabetes RElated to Acute Pancreatitis and Its Mechanisms

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT05197920·Recruiting

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Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With nAMD

for Neovascular Age-Related Macular Degeneration (nAMD)

16 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: All ages

Code: NCT05210803·Enrolling By Invitation

Trial of Cemiplimab, or Cemip-Chemo Followed by Biomarker-guided Treatment for Pts w/HPV H&N Ca

for HPV-Related Squamous Cell Carcinoma

Drug: Cemiplimab

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT04988074·Phase 2·Recruiting

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Extension Study of Infigratinib in Children With Achondroplasia (ACH)

for Achondroplasia

8 locations incl. Oakland

Sponsor: QED Therapeutics, a BridgeBio company

Sex: All·Age: 3 - 18

Code: NCT05145010·Phase 2·Enrolling By Invitation

American Lung Association (ALA) Lung Health Cohort

for Lung Diseases

37 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT04543461·Recruiting

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Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

19 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting

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Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs

for Interstitial Lung Disease

14 locations incl. Phoenix

Sponsor: Paragonix Technologies

Sex: All·Age: All ages

Code: NCT04930289·Enrolling By Invitation

Cleidocranial Dysplasia (CCD): From Genotype to Phenotype and Considerations for Care

for Cleidocranial Dysostosis

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05368064·Enrolling By Invitation

RA-PRO PRAGMATIC TRIAL

for Rheumatoid Arthritis

48 locations incl. Auburn

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT04692493·Phase 3·Recruiting

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Genomic Predictors of Recurrent Pregnancy Loss

for Recurrent Pregnancy Loss

10 locations incl. Aurora

Sponsor: Yale University

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05444283·Recruiting

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IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study)

for Nontuberculous Mycobacterium Infection

10 locations incl. Birmingham

Sponsor: Chris Goss

Sex: All·Age: 18+

Code: NCT04294043·Phase 1·Recruiting

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Long Term Follow up of the LTOG Cohort

for Lung Transplant Failure and Rejection

10 locations incl. Birmingham

Sponsor: University of Pennsylvania

Sex: All·Age: 13+

Code: NCT04787822·Enrolling By Invitation

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

for Pulmonary Arterial Hypertension

27 locations incl. Phoenix

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07218029·Phase 3·Recruiting

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Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

for Castration-Resistant Prostate Carcinoma

4 locations incl. Baltimore

Sponsor: University of Washington

Sex: Male·Age: 18+

Code: NCT04489719·Recruiting

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A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

for Diabetes Mellitus, Type 1

12 locations incl. Duarte

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 65

Code: NCT04786262·Phase 3·Recruiting

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Child and Adolescent Registry for Participants With Narcolepsy

for Narcolepsy

25 locations incl. Phoenix

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: Up to 17

Code: NCT04899947·Recruiting

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Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults

for Glioblastoma

14 locations incl. Birmingham

Sponsor: Sabine Mueller, MD, PhD

Sex: All·Age: 6 Months - 25

Code: NCT04323046·Phase 1·Recruiting

Apply to this trial