American Lung Association (ALA) Lung Health Cohort
Part of paid clinical trials in Birmingham, Alabama.
- Sponsor
- Johns Hopkins University
- Study ID
- NCT04543461
- Status
- Recruiting
Conditions
- Lung Diseases
Eligibility Criteria
- Sex
- ALL
- Age
- 25 Years - 35 Years
- Healthy Volunteers
- Accepted
Study Details
The ALA-LHC is a longitudinal, multi-center cohort study that will enroll approximately 4,000 young adults between the ages of 25-35 who do not have severe lung disease. The overarching objective of the ALA-LHC is to establish a national cohort of young adults for the purpose of defining lung health and developing targets to intercept chronic lung disease at its earliest stages.
Key Dates
- Start date
- Oct 29, 2021
- Status verified
- Feb 2026
- Primary completion
- Sep 30, 2026
- Completion
- Sep 30, 2026
Study Design
- Enrollment
- 4,000 participants (estimated)
Primary Outcome Measure
Pre-bronchodilator measurement of Forced Expiratory Volume in one second (FEV1) [ Time Frame: Baseline ]
Central Contacts
- Elizabeth Sugar, PhD443-287-3170
- Curt Reynolds, MAS410-614-2422
Locations (37)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| University Of Alabama | Birmingham | Alabama | 35294 | Michael Wells, MD (PRINCIPAL_INVESTIGATOR) |
| University of Arizona-Tuscon | Tucson | Arizona | 85724 | Fernando Martinez, PhD, MSPH (PRINCIPAL_INVESTIGATOR) |
| University of California, Los Angeles | Los Angeles | California | 90095 | Igor Barjaktarevic (PRINCIPAL_INVESTIGATOR) |
| University of California, San Francisco | San Francisco | California | 94143 | Stephanie Christenson, MD (PRINCIPAL_INVESTIGATOR) |
| University of Colorado | Aurora | Colorado | 80045 | - |
| National Jewish Health | Denver | Colorado | 80206 | Barry Make, MD (PRINCIPAL_INVESTIGATOR) |
| Nemours Children's Jacksonville | Jacksonville | Florida | 32207 | Kathryn Blake, PharmD (PRINCIPAL_INVESTIGATOR) |
| University of Florida, Jacksonville | Jacksonville | Florida | 32209 | Vandana Seeram, MD (PRINCIPAL_INVESTIGATOR) |
| Northwestern University | Chicago | Illinois | 60611 | Ravi Kalhan, MD (PRINCIPAL_INVESTIGATOR) Lewis Smith, MD (PRINCIPAL_INVESTIGATOR) |
| Rush Universtiy | Chicago | Illinois | 60612 | James Moy, MD (PRINCIPAL_INVESTIGATOR) |
| University of Chicago | Chicago | Illinois | 60637 | - |
| University of Illinois at Chicago | Chicago | Illinois | 60608 | Lynn Gerald, PhD (PRINCIPAL_INVESTIGATOR) |
| St. Vincent's Health System | Indianapolis | Indiana | 46260 | - |
| University of Iowa | Iowa City | Iowa | 52242 | Alejandro Comellas, MD (PRINCIPAL_INVESTIGATOR) |
| University of Kansas | Kansas City | Kansas | 66103 | Mario Castro, MD, MPH (PRINCIPAL_INVESTIGATOR) |
| Johns Hopkins University | Baltimore | Maryland | 21218 | Nadia Hansel (PRINCIPAL_INVESTIGATOR) |
| Brigham and Women's | Boston | Massachusetts | 02115 | - |
| University of Michigan | Ann Arbor | Michigan | 48109 | MeiLan Han, MD (PRINCIPAL_INVESTIGATOR) Alan Baptist, MD, MPH (PRINCIPAL_INVESTIGATOR) |
| Presbyterian Brooklyn Methodist Hospital | Brooklyn | New York | 11215 | 718-780-5906 Jerem Weingarten, MD, MBA, MS (PRINCIPAL_INVESTIGATOR) |
| New York Medical College | Hawthorne | New York | 10532 | Allen Dozor, MD (PRINCIPAL_INVESTIGATOR) |
| Columbia University | New York | New York | 10032 | Emily DiMango, MD (PRINCIPAL_INVESTIGATOR) |
| Cornell University | New York | New York | 10032 | Robert Kaner (PRINCIPAL_INVESTIGATOR) |
| Mt. Sinai, NYC | New York | New York | 10029 | Linda Rogers, MD (PRINCIPAL_INVESTIGATOR) |
| New York University | New York | New York | 10016 | - |
| University of Rochester | Rochester | New York | 14642 | 585-369-6769 Sandhya Khurana, MD (PRINCIPAL_INVESTIGATOR) |
| University of North Carolina Hospital | Chapel Hill | North Carolina | 27517 | - |
| Duke University | Durham | North Carolina | 27710 | Loretta Que, MD (PRINCIPAL_INVESTIGATOR) |
| Wake Forest School of Medicine | Winston-Salem | North Carolina | 27104 | Wendy Moore, MD (PRINCIPAL_INVESTIGATOR) |
| Ohio State University | Columbus | Ohio | 43210 | Philip Diaz (PRINCIPAL_INVESTIGATOR) |
| Temple University | Philadelphia | Pennsylvania | 19140 | Nathaniel Marchetti, MD (PRINCIPAL_INVESTIGATOR) |
| University of Pittsburg-Emphysema/COPD Research Center | Pittsburgh | Pennsylvania | 15213 | Elizabeth Stempkowski Frank Sciurba, MD (PRINCIPAL_INVESTIGATOR) |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | Charlie Strange, MD (PRINCIPAL_INVESTIGATOR) |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37235 | Leonard Bacharier (PRINCIPAL_INVESTIGATOR) |
| Baylor College of Medicine | Houston | Texas | 77030 | Nicola Hanania, MD (PRINCIPAL_INVESTIGATOR) |
| University of Vermont | Colchester | Vermont | 05446 | Charles Irvin, PhD (PRINCIPAL_INVESTIGATOR) |
| University of Washington | Seattle | Washington | 98108 | 206-764-2558 David Au, MD (PRINCIPAL_INVESTIGATOR) |
| University of Wisconsin Madison | Madison | Wisconsin | 53792 | - |
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