Paid Clinical Trials in Alabama

Alabama has 1,359 paid clinical trials enrolling now across cities including Birmingham, Mobile and Huntsville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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1,359 clinical trials

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A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma

for Asthma

30 locations incl. Montgomery

Sponsor: AstraZeneca

Sex: All·Age: 5 - 11

Code: NCT06023589·Phase 3·Recruiting

Apply to this trial

Responding With Evidence and Access for Childhood Headaches

for Headache

15 locations incl. Birmingham

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 10 - 17

Code: NCT05889624·Recruiting

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A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis

for Atopic Dermatitis

Drug: PF-07275315

52 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT05995964·Phase 2·Recruiting

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The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial

for Coronary Artery Disease

9 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05618353·Phase 4·Recruiting

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Cabozantinib and Dostarlimab in Recurrent Gynecologic Carcinosarcoma

for Gynecologic Cancer

Drug: Cabozantinib

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18+

Code: NCT05559879·Phase 1, Phase 2·Recruiting

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A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

for Cardiovascular Disorder

31 locations incl. Mobile

Sponsor: Children's Oncology Group

Sex: All·Age: 7+

Code: NCT05705531·Recruiting

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A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED

for Persistent Corneal Epithelial Defect

21 locations incl. Dothan

Sponsor: Glaukos Corporation

Sex: All·Age: 2+

Code: NCT05966493·Phase 2·Recruiting

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A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

for Uterine Fibroids

Drug: Relugolix

120 locations incl. Mobile

Sponsor: Sumitomo Pharma Switzerland GmbH

Sex: Female·Age: 18 - 50

Code: NCT05862272·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

for Primary IgA Nephropathy

40 locations incl. Alabaster

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT05797610·Phase 3·Recruiting

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Safety and Tolerability of Pirfenidone in Acute Pancreatitis

for Pancreatitis, Acute

2 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 85

Code: NCT05350371·Phase 1, Phase 2·Recruiting

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Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease

for cGVHD

32 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT05919511·Recruiting

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Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV

for HIV Infections

3 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT06013579·Recruiting

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A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.

for Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations

18 locations incl. Birmingham

Sponsor: Taiho Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05967689·Phase 2·Recruiting

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A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

for Type 1 Diabetes Mellitus With Hypoglycemia

38 locations incl. Birmingham

Sponsor: Zucara Therapeutics Inc.

Sex: All·Age: 18 - 75

Code: NCT05762107·Phase 2·Recruiting

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Trauma Resuscitation With Low-Titer Group O Whole Blood or Products

for Wounds and Injuries

13 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 15+

Code: NCT05638581·Phase 3·Recruiting

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Integrated e-Health (Electronic Health) for HIV and Substance Use Disorders in Justice Involved Women

for HIV

2 locations incl. Birmingham

Sponsor: Yale University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT05547048·Phase 4·Recruiting

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Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

for Glioblastoma, IDH-wildtype

8 locations incl. Birmingham

Sponsor: Orbus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05879367·Phase 1·Recruiting

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AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

for Relapsed/Refractory Multiple Myeloma

36 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05850234·Phase 1, Phase 2·Recruiting

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AI Ready and Exploratory Atlas for Diabetes Insights

for Type 2 Diabetes

3 locations incl. Birmingham

Sponsor: University of Washington

Sex: All·Age: 40 - 85

Code: NCT06002048·Enrolling By Invitation

Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

40 locations incl. Birmingham

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting

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Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for Locally Advanced Lung Non-Small Cell Carcinoma

470 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05624996·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Inadequately Controlled Moderate to Severe Asthma

for Moderate to Severe Asthma

Drug: Povorcitinib

26 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18 - 65

Code: NCT05851443·Phase 2·Recruiting

Apply to this trial

Predicton of Sepsis Recovery Performance Subtypes Pilot Study

for Sepsis

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 80

Code: NCT05912413·Recruiting

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Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

for Psychosis Associated With Alzheimer's Disease

Drug: KarXT

147 locations incl. Homewood

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 55 - 90

Code: NCT05980949·Phase 3·Recruiting

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Study of Treatment for HPV16+ ASC-US or LSIL

for ASC-US

2 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 19+

Code: NCT03913117·Phase 1·Recruiting

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Prehabilitation Feasibility Among Older Adults Undergoing Transplantation

for Multiple Myeloma

1 location in Birmingham

Sponsor: Noha Mohamed Sharafeldin

Sex: All·Age: 60+

Code: NCT05642884·Recruiting

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ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors

for Non Small Cell Lung Cancer

46 locations incl. Dothan

Sponsor: OncoC4, Inc.

Sex: All·Age: 18+

Code: NCT05671510·Phase 3·Recruiting

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DCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors

for Advanced or Metastatic Solid Tumors

14 locations incl. Birmingham

Sponsor: DynamiCure Biotechnology

Sex: All·Age: 18+

Code: NCT05785754·Phase 1·Recruiting

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A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

for Chronic Obstructive Pulmonary Disease

68 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 40 - 90

Code: NCT05878769·Phase 3·Recruiting

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Lupus Landmark Study: A Prospective Registry and Biorepository

for Systemic Lupus Erythematosus (SLE)

19 locations incl. Birmingham

Sponsor: Lupus Research Alliance

Sex: All·Age: 18 - 110

Code: NCT05934149·Recruiting

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A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

for Hidradenitis Suppurativa

Drug: Upadacitinib

87 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 12+

Code: NCT05889182·Phase 3·Recruiting

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Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

for Colorectal Polyp

18 locations incl. Birmingham

Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All·Age: 65 - 82

Code: NCT05612347·Recruiting

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Determining the Role of Social Reward Learning in Social Anhedonia

for Psychosis

2 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 35

Code: NCT05617898·Recruiting

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Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

for Anatomic Stage II Breast Cancer AJCC v8

820 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05812807·Phase 3·Recruiting

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Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab

for Relapsing Multiple Sclerosis

36 locations incl. Birmingham

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT05877963·Phase 3·Recruiting

Apply to this trial

The HOME Study (Healthy Options Made Easy): Telehealth Nutrition Sessions for People Living With Brain Injury

for Brain Injuries

1 location in Tuscaloosa

Sponsor: University of Alabama, Tuscaloosa

Sex: All·Age: 18+

Code: NCT05965947·Recruiting

Apply to this trial

Alzheimer's Disease Neuroimaging Initiative 4

for Mild Cognitive Impairment

59 locations incl. Birmingham

Sponsor: University of Southern California

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05617014·Enrolling By Invitation

MAGESTIC Trial: MiRNA in Detecting Active Germ Cell Tumors in Early Suspected and MetastaTIC Disease Trial

for Malignant Testicular Germ Cell Tumor

5 locations incl. Birmingham

Sponsor: University of Southern California

Sex: Male·Age: 18+

Code: NCT06060873·Recruiting

Apply to this trial

Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease

for Sickle Cell Disease

9 locations incl. Birmingham

Sponsor: RTI International

Sex: All·Age: 18+

Code: NCT06385886·Recruiting

Apply to this trial

Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy

for Malignant Solid Neoplasm

36 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642611·Phase 3·Recruiting

Apply to this trial