Povorcitinib Clinical Trials (2026): 16 Studies for Healthy Participants & Hidradenitis Suppurativa (HS)

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: .

16 Povorcitinib clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 6 indications (including Healthy Participants & Hidradenitis Suppurativa (HS)) and 4,737 total planned enrollment. 8 Phase 3 Povorcitinib trials and 3 Phase 2 are listed. 4 Povorcitinib clinical trials are actively recruiting at 86 U.S. sites across 27 states. Most recent activity: NCT07213973 (Mar 2028).

Where to Participate: All Povorcitinib Trial Sites in the U.S. (86 sites across 27 states)

Every actively recruiting Povorcitinibtrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

StateFacilityCityTrialMap
ALInvestigative Site US086Birmingham35244NCT06855498Map
AZInvestigative Site US004Phoenix85006NCT06855498Map
AZMedical Dermatology Specialists PhoenixPhoenix85006NCT07213973Map
AZSaguaro DermatologyPhoenix85008NCT07213973Map
CAKern Allergy Medical Clinic, IncBakersfield93301NCT05851443Map
CAInvestigative Site US076Fountain Valley92708-3701NCT06855498Map
CAInvestigative Site US077Fremont94538NCT06855498Map
CAInvestigative Site US020Laguna Niguel92677NCT06855498Map
CAInvestigative Site US036Los Angeles90033NCT06855498Map
CAInvestigative Site US067Los Angeles90045NCT06855498Map
CAInvestigative Site US060Northridge91325NCT06855498Map
CAInvestigative Site US037Oakland94611NCT06855498Map
CAInvestigative Site US089Santa Monica90404NCT06855498Map
FLInvestigative Site US002Boca Raton33486NCT06855498Map
FLInvestigative Site US062Coral Gables33134NCT06855498Map
FLInvestigative Site US084Coral Gables33146NCT06855498Map
FLDirect Helpers Research CenterHialeah33012NCT05851443Map
FLInvestigative Site US017Hialeah33012NCT06855498Map
FLQway ResearchHialeah33010NCT05851443Map
FLInvestigative Site US019Hollywood33021-6746NCT06855498Map
FLCare Research IncMiami33130NCT05851443Map
FLInvestigative Site US015Miami33136NCT06855498Map
FLSkin Research of South Florida, LlcMiami33173NCT07213973Map
FLUniversity of Miami Miller School of MedicineMiami33136NCT07213973Map
FLVerus Clinical Research CorpMiami33135NCT05851443Map
FLInvestigative Site US072Miami Lakes33014NCT06855498Map
FLInvestigative Site US023North Miami Beach33162NCT06855498Map
FLInvestigative Site US029Ocala34470NCT06855498Map
FLInvestigative Site US001Tampa33615NCT06855498Map
FLInvestigative Site US005Tampa33613NCT06855498Map
FLInvestigative Site US035Tampa33607NCT06855498Map
FLTrueblue Clinical ResearchTampa33607NCT07213973Map
FLInvestigative Site US066West Palm Beach33401NCT06855498Map
FLInvestigative Site US070West Palm Beach33401NCT06855498Map
GAAdvanced Medical Research PcSandy Springs30328NCT07213973Map
ILInvestigative Site US093Chicago60657NCT06855498Map
ILEndeavor Health Medical GroupSkokie60077NCT07213973Map
ILInvestigative Site US039West Dundee60118NCT06855498Map
INInvestigative Site US008Indianapolis46250NCT06855498Map
INInvestigative Site US064West Lafayette47906NCT06855498Map
KSDermatology Skin Cancer Center LeawoodLeawood66211NCT07213973Map
KYEquity MedicalBowling Green42104NCT07213973Map
LAInvestigative Site US012Baton Rouge70809NCT06855498Map
LAInvestigative Site US057New Orleans70115NCT06855498Map
MDInvestigative Site US038Baltimore21287-0876NCT06855498Map
MDJohns Hopkins Univ Schl of MedicineBaltimore21205NCT07213973Map
MAInvestigative Site US030Boston02215NCT06855498Map
MAInvestigative Site US048Brighton02135NCT06855498Map
MIInvestigative Site US061Ann Arbor48103NCT06855498Map
MIOakland Hills Dermatology PcAuburn Hills48326NCT07213973Map
MIWayne State University Physician Group DermatologyDetroit48201NCT07213973Map
MIInvestigative Site US091Troy48084NCT06855498Map
MIRevival Research Institute, Llc TroyTroy48084NCT07213973Map
MIInvestigative Site US042Waterford48328NCT06855498Map
MNAxis ClinicalsDilworth56529NCT07588139Map
MNInvestigative Site US011Minneapolis55455NCT06855498Map
MOInvestigative Site US088Saint Joseph64506NCT06855498Map
MOInvestigative Site US016St Louis63110NCT06855498Map
MOWashington UniversitySt Louis63110NCT07213973Map
MTBoeson Research Missoula 2825 Fort Missoula RdMissoula59804NCT07213973Map
NHInvestigative Site US007Portsmouth03801NCT06855498Map
NMUniversity of New Mexico HospitalAlbuquerque87102NCT07213973Map
NYInvestigative Site US082East Syracuse13057NCT06855498Map
NYInvestigative Site US034New York10028-3135NCT06855498Map
NYInvestigative Site US065New York10128NCT06855498Map
NYInvestigative Site US081New York10075NCT06855498Map
NCInvestigative Site US031Chapel Hill27516NCT06855498Map
OHInvestigative Site US028Bexley43209NCT06855498Map
OHInvestigative Site US025Cincinnati45219NCT06855498Map
OHInvestigative Site US073Columbus43215NCT06855498Map
OKInvestigative Site US085Oklahoma City73170NCT06855498Map
PAInvestigative Site US069Plymouth Meeting19462NCT06855498Map
TXHowland Allergy and Asthma Pllc Dba Orion Clinical ResearchAustin78759NCT05851443Map
TXBellaire Dermatology Associates BdaBellaire77401NCT07213973Map
TXInvestigative Site US021Bellaire77401NCT06855498Map
TXInvestigative Site US010Dallas75246NCT06855498Map
TXInvestigative Site US078Dallas75230NCT06855498Map
TXTexas Dermatology Research CenterDallas75246NCT07213973Map
TXLinq Research, LlcPearland77584NCT05851443Map
TXInvestigative Site US083San Antonio78218NCT06855498Map
TXInvestigative Site US068Webster77598NCT06855498Map
UTInvestigative Site US063South Jordan84095NCT06855498Map
UTJordan Valley Dermatology CenterSouth Jordan84095NCT07213973Map
VAInvestigative Site US027Norfolk23502NCT06855498Map
VAInvestigative Site US094Richmond23226NCT06855498Map
WAInvestigative Site US003Spokane99202NCT06855498Map

Povorcitinib clinical trials at a glance: phase × recruitment status

Phaserecruitingactive not recruitingcompletedTotal
P1145
P2213
P31528

Recruiting Povorcitinib clinical trials (4)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT IDTitlePhaseIndicationEnrollmentStarted
NCT07213973Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis SuppurativaP2Hidradenitis Suppurativa (HS)40Feb 2026
NCT06855498STOP-LTRRollover Study for Participants Previously Enrolled in Clinical Trials of PovorcitinibP3Hidradenitis Suppurativa (HS)600Feb 2025
NCT05851443A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Inadequately Controlled Moderate to Severe AsthmaP2Moderate to Severe Asthma240Jul 2023
NCT07588139A Study to Evaluate Dermal Open-Flow Microperfusion and Plasma Pharmacokinetic Study of Multiple Doses of Oral Povorcitinib or Topical Ruxolitinib Cream in Healthy Adult ParticipantsP1Healthy Participants24May 2026

Povorcitinib clinical trials by indication

Healthy Participants (5)

NCTAcronymPhaseStatusTitle
NCT07588139P1recruitingA Study to Evaluate Dermal Open-Flow Microperfusion and Plasma Pharmacokinetic Study of Multiple Doses of Oral Povorcitinib or Topical Ruxolitinib Cream in Healthy Adult Participants
NCT06416800P1completedA Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult Participants
NCT06505265P1completedA Study to Evaluate Skin and Plasma Pharmacokinetic of Multiple Doses of Povorcitinib After Oral Administration in Healthy Participants
NCT06441318P1completedA Study to Evaluate the Effect of Povorcitinib on the QT/QTc Interval in Healthy Participants
NCT06380205P1completedA Study to Evaluate the Drug Interaction Between Povorcitinib and the Oral Contraceptive Levonorgestrel/Ethinyl Estradiol in Healthy Adult Females

Hidradenitis Suppurativa (HS) (5)

NCTAcronymPhaseStatusTitle
NCT07213973P2recruitingPharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
NCT06855498STOP-LTRP3recruitingRollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib
NCT06212999STOP-HS LTEP3active not recruitingA Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa
NCT05620823STOP-HS1P3completedA Study to Evaluate the Efficacy and Safety of Povorcitinib (INCB054707) in Participants With Moderate to Severe Hidradenitis Suppurativa
NCT05620836STOP-HS2P3completedA Study to Evaluate the Efficacy and Safety of Povorcitinib (INCB054707) in Participants With Moderate to Severe Hidradenitis Suppurativa (HS)

Prurigo Nodularis (2)

NCTAcronymPhaseStatusTitle
NCT06516965STOP-PN2P3active not recruitingA Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)
NCT06516952STOP-PN1P3active not recruitingA Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN1)

NonSegmental Vitiligo (2)

NCTAcronymPhaseStatusTitle
NCT06113471STOP-V2P3active not recruitingA Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V2)
NCT06113445STOP-V1P3active not recruitingA Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V1)

Urticaria (1)

NCTAcronymPhaseStatusTitle
NCT05936567P2completedStudy Evaluating the Efficacy and Safety of Povorcitinib in Adults With Chronic Spontaneous Urticaria

Moderate to Severe Asthma (1)

NCTAcronymPhaseStatusTitle
NCT05851443P2recruitingA Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Inadequately Controlled Moderate to Severe Asthma

Povorcitinib pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

AcronymNCTPhaseStatusIndicationEnrollmentPubMed
STOP-LTRNCT06855498P3recruitingHidradenitis Suppurativa (HS)600
STOP-PN2NCT06516965P3active not recruitingPrurigo Nodularis346
STOP-PN1NCT06516952P3active not recruitingPrurigo Nodularis349
STOP-V2NCT06113471P3active not recruitingNonSegmental Vitiligo450
STOP-V1NCT06113445P3active not recruitingNonSegmental Vitiligo467
STOP-HS LTENCT06212999P3active not recruitingHidradenitis Suppurativa (HS)617
STOP-HS1NCT05620823P3completedHidradenitis Suppurativa (HS)608
STOP-HS2NCT05620836P3completedHidradenitis Suppurativa (HS)619

All Povorcitinib trials (16)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT IDAcronymTitlePhaseStatusEnrollmentSponsorStarted
NCT07213973Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis SuppurativaP2recruiting40Incyte CorporationFeb 2026
NCT06855498STOP-LTRRollover Study for Participants Previously Enrolled in Clinical Trials of PovorcitinibP3recruiting600Incyte CorporationFeb 2025
NCT06516965STOP-PN2A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)P3active not recruiting346Incyte CorporationOct 2024
NCT06516952STOP-PN1A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN1)P3active not recruiting349Incyte CorporationOct 2024
NCT06113471STOP-V2A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V2)P3active not recruiting450Incyte CorporationNov 2023
NCT06113445STOP-V1A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V1)P3active not recruiting467Incyte CorporationNov 2023
NCT05851443A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Inadequately Controlled Moderate to Severe AsthmaP2recruiting240Incyte CorporationJul 2023
NCT06212999STOP-HS LTEA Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis SuppurativaP3active not recruiting617Incyte CorporationJan 2024
NCT07588139A Study to Evaluate Dermal Open-Flow Microperfusion and Plasma Pharmacokinetic Study of Multiple Doses of Oral Povorcitinib or Topical Ruxolitinib Cream in Healthy Adult ParticipantsP1recruiting24Incyte CorporationMay 2026
NCT05620823STOP-HS1A Study to Evaluate the Efficacy and Safety of Povorcitinib (INCB054707) in Participants With Moderate to Severe Hidradenitis SuppurativaP3completed608Incyte CorporationDec 2022
NCT05620836STOP-HS2A Study to Evaluate the Efficacy and Safety of Povorcitinib (INCB054707) in Participants With Moderate to Severe Hidradenitis Suppurativa (HS)P3completed619Incyte CorporationFeb 2023
NCT05936567Study Evaluating the Efficacy and Safety of Povorcitinib in Adults With Chronic Spontaneous UrticariaP2completed136Incyte CorporationJul 2023
NCT06416800A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult ParticipantsP1completed71Incyte CorporationJun 2024
NCT06505265A Study to Evaluate Skin and Plasma Pharmacokinetic of Multiple Doses of Povorcitinib After Oral Administration in Healthy ParticipantsP1completed18Incyte CorporationAug 2024
NCT06441318A Study to Evaluate the Effect of Povorcitinib on the QT/QTc Interval in Healthy ParticipantsP1completed128Incyte CorporationJul 2024
NCT06380205A Study to Evaluate the Drug Interaction Between Povorcitinib and the Oral Contraceptive Levonorgestrel/Ethinyl Estradiol in Healthy Adult FemalesP1completed24Incyte CorporationMay 2024

Povorcitinib clinical trials: frequently asked questions

How many Povorcitinib clinical trials are there?
16 Povorcitinib clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 4 are actively recruiting participants. 7 are marked completed.
Are Povorcitinib clinical trials recruiting in 2026?
Yes — 4 Povorcitinib trials are actively recruiting in 2026, with 86 U.S. sites across 27 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Povorcitinib being studied for?
Povorcitinib is being studied for Healthy Participants, Hidradenitis Suppurativa (HS), NonSegmental Vitiligo, Prurigo Nodularis, Moderate to Severe Asthma and 6 more. The trials are grouped by indication on this page.
What phase is Povorcitinib in?
Povorcitinib clinical trials span 8 Phase 3, 3 Phase 2, 5 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Povorcitinib clinical trials?
The lead sponsor across the most Povorcitinib trials is Incyte Corporation. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Povorcitinibas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

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