A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)

Part of paid clinical trials in Phoenix, Arizona.

Sponsor
Incyte Corporation
Study ID
NCT06516965
Phase
PHASE3
Status
Active Not Recruiting

Conditions

  • Prurigo Nodularis

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

Study Details

The purpose of this study is to evaluate effect of povorcitinib on itch and skin lesions in participants with prurigo nodularis.

Key Dates

Start date
Oct 10, 2024
Status verified
Apr 2026
Primary completion
Oct 19, 2026
Completion
May 3, 2027

Study Design

Enrollment
346 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Povorcitinib Dose 1
    Povorcitinib at the protocol-defined dose.
  • Experimental: Povorcitinib Dose 2
    Povorcitinib at the protocol-defined dose.
  • Placebo Comparator: Placebo
    Placebo at the protocol-defined dose.

Primary Outcome Measure

Proportion of participants achieving Itch NRS4 and IGA-CPG-S-TS at Week 24 [ Time Frame: Week 24 ]

Locations (28)

FacilityCityStateZIPSite coordinators
Medical Dermatology Specialists PhoenixPhoenixArizona85006-
Investigate MdScottsdaleArizona85255-
First Oc Dermatology Research IncFountain ValleyCalifornia92708-3701-
Clinical Science Institute Clinical Research Specialists IncSanta MonicaCalifornia90404-
Center For Clinical and Cosmetic ResearchAventuraFlorida33180-
Schweiger DermatologyBoca RatonFlorida33428-
Direct Helpers Research CenterHialeahFlorida33012-
Skin Care Research, LlcHollywoodFlorida33201-
Ziaderm Research, LlcMiamiFlorida33162-
Nodal Medical Center, LlcTampaFlorida33607-
Trueblue Clinical Research Moore Clinical Research, Inc McR Tampa Clinic LocationTampaFlorida33609-
Dermatology Specialists ResearchLouisvilleKentucky40241-
University of Maryland School of MedicineBaltimoreMaryland21201-
Dermatology Associates PcRockvilleMaryland20850-
Metro Boston Clinical PartnersBrightonMassachusetts02135-3511-
Fivenson DermatologyAnn ArborMichigan48103-
Henry Ford Health SystemDetroitMichigan48202-
Michigan Dermatology InstituteWaterfordMichigan48328-
Allcutis Research, LlcPortsmouthNew Hampshire03801-
Schweiger DermatologyHackensackNew Jersey07601-
OPTISKINNew YorkNew York10128-
University of Cincinnati Cancer InstituteCincinnatiOhio45267-
Central Sooner ResearchOklahoma CityOklahoma73118-
Paddington Testing Co IncPhiladelphiaPennsylvania19103-
Yardley Dermatology AssociatesYardleyPennsylvania19067-
Modern Research Associates PllcDallasTexas75231-
University of Utah Midvalley DermatologyMurrayUtah84107-
Aesthetic General Dermatology of SeattleBurienWashington98168-

Find similar trials in Phoenix, AZ

By research site
Medical Dermatology Specialists Phoenix· Phoenix, AZInvestigate Md· Scottsdale, AZFirst Oc Dermatology Research Inc· Fountain Valley, CAClinical Science Institute Clinical Research Specialists Inc· Santa Monica, CACenter For Clinical and Cosmetic Research· Aventura, FLSchweiger Dermatology· Boca Raton, FL

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