A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN1)

Part of paid clinical trials in Birmingham, Alabama.

Sponsor
Incyte Corporation
Study ID
NCT06516952
Phase
PHASE3
Status
Active Not Recruiting

Conditions

  • Prurigo Nodularis

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

Study Details

The purpose of this study is to evaluate effect of povorcitinib on itch and skin lesions in participants with prurigo nodularis.

Key Dates

Start date
Oct 10, 2024
Status verified
May 2026
Primary completion
Oct 19, 2026
Completion
May 3, 2027

Study Design

Enrollment
349 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Povorcitinib Dose 1
    Povorcitinib at the protocol-defined dose.
  • Experimental: Povorcitinib Dose 2
    Povorcitinib at the protocol-defined dose.
  • Placebo Comparator: Placebo
    Placebo at the protocol-defined dose.

Primary Outcome Measure

Proportion of participants achieving Itch NRS4 and IGA-CPG-S-TS at Week 24 [ Time Frame: Week 24 ]

Locations (31)

FacilityCityStateZIPSite coordinators
Cahaba DermatologyBirminghamAlabama35244-
Banner - University Medicine Multispecialty Services ClinicTucsonArizona85718-
Premier Dermatology Clinical Trials Institute At Northwest ArkansasFayettevilleArkansas72703-
Burke Pharmaceutical ResearchHot SpringsArkansas71913-
Dermatology Research AssociatesLos AngelesCalifornia90045-
NorthridgeNorthridgeCalifornia91325-
Rendon Center the Dermatology and Aesthetic CenterBoca RatonFlorida33486-
Driven Research LlcCoral GablesFlorida33134-
University of Miami Miller School of MedicineMiamiFlorida33136-
Research Institute of the Southeast, LlcWest Palm BeachFlorida33401-
Center For Medical Dermatology and Immunology ResearchChicagoIllinois60657-
Chicago Cosmetic Surgery and DermatologyChicagoIllinois60654-
Illinois Dermatology Institute the Chicago LoopChicagoIllinois60602-
Northshore University HealthsystemSkokieIllinois60077-
Dermatology Specialists Research IndianaClarksvilleIndiana47129-
Oakland Hills DermatologyAuburn HillsMichigan48326-
Hamzavi DermatologyFort GratiotMichigan48059-
Somerset Skin CentreTroyMichigan48084-
Medisearch Clinical TrialsSaint JosephMissouri64506-
Washington University School of MedicineSt LouisMissouri63110-
The University of New Mexico Unm Health Sciences Center HscAlbuquerqueNew Mexico87131-
Montefiore Medical CenterEast SyracuseNew York13057-
Skin Center Dermatology GroupNew YorkNew York10956-
Stony Brook Dermatology AssociatesStony BrookNew York11790-
Centricity Research ColumbusColumbusOhio43213-
Wright State Physicians Health CenterDaytonOhio45324-
International Clinical Research Tennessee LlcMurfreesboroTennessee37130-
Dermatology Treatment and Research CenterDallasTexas75230-
Sweetwater DermatologySugar LandTexas77479-
Center For Clinical StudiesWebsterTexas77598-
Frontier DermatologyMill CreekWashington98012-

Find similar trials in Birmingham, AL

By research site
Cahaba Dermatology· Birmingham, ALBanner - University Medicine Multispecialty Services Clinic· Tucson, AZPremier Dermatology Clinical Trials Institute At Northwest Arkansas· Fayetteville, ARBurke Pharmaceutical Research· Hot Springs, ARDermatology Research Associates· Los Angeles, CANorthridge· Northridge, CA

Related Studies