Oncology Clinical Trials in Toledo, OH
As of June 2026, 35 paid clinical trials are recruiting for Oncology in Toledo, Ohio. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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35 clinical trials for Oncology
·Clear filters·↓ Download CSVAn Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma
Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier
Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma
Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer
Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)
Project: Every Child for Younger Patients With Cancer
About research studies in Toledo
Toledo has approximately 156 recruiting research studies across a wide range of therapeutic areas. Ohio is home to The Ohio State University Wexner Medical Center, Cleveland Clinic, Cincinnati Children's, and University Hospitals Cleveland Medical Center — collectively running clinical trials across every major therapeutic area.
Top Research Study Locations in Toledo
Researchers run research studies in Toledo, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mercy Health - Saint Anne Hospital | Stage IV Lung Cancer AJCC v8, Malignant Solid Neoplasm, Stage IIIB Lung Cancer AJCC v8 | 31 |
| ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital | B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Ganglioneuroblastoma, Nodular | 30 |
| Mercy Health - Saint Vincent Hospital | Malignant Solid Neoplasm, Chronic Lymphocytic Leukemia, Melanoma | 19 |
| ProMedica Toledo Hospital | Acute Ischemic Stroke, Heart Failure, Acute Disease | 15 |
| Toledo Clinic Cancer Centers-Toledo | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 14 |
| Mercy Health Sylvania Radiation Oncology Center | Malignant Solid Neoplasm, Melanoma, RISS Stage I Plasma Cell Myeloma | 11 |
| Mercy Health - St. Vincent Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 6 |
| Toledo Clinic Cancer Center | Bladder Carcinoma, Cancer Harboring BRAF Alterations, Colorectal Cancer | 6 |
| University of Toledo Medical Center | Atrial Fibrillation (AF), Chronic Pain, Pain | 6 |
| Mercy Health St. Vincent Medical Center | Acute Ischemic Stroke, Chronic Subdural Hematoma, Heart Failure | 5 |
| University of Toledo | Acute Myocardial Infarction (AMI), Cardiovascular Risk, Castration Levels of Testosterone | 5 |
| ProMedica | Acute Myocardial Infarction (AMI), Cardiovascular Risk, Ischemic Stroke | 4 |
| Toledo Institute of Clinical Research | C. Diff Infection, C.Difficile Diarrhea, CDI | 3 |
| Asthma & Allergy Center - Toledo | Asthma, Chronic Obstructive Pulmonary Disease | 3 |
| ADARx Clinical Site | HAE, Hereditary Angioedema - Type 1, Hereditary Angioedema - Type 2 | 2 |
| Saint Vincent Mercy Medical Center | Acral Lentiginous Melanoma, Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8 | 2 |
| Toledo Children's Hospital | Cystic Fibrosis, Cystic Fibrosis (CF), Cystic Fibrosis Pulmonary Exacerbation | 2 |
| Toledo Institute of Clinical Research Inc. | Asthma, Moderate to Severe Chronic Obstructive Pulmonary Disease | 2 |
| Clinical Trial Site | Advanced Breast Cancer, Breast Cancer, ER Positive Breast Cancer | 1 |
| Consulting Orthopaedic Associates | Spinal Stenosis Lumbar | 1 |
| Corxel Investigational Site | Acute Ischemic Stroke | 1 |
| Deca Health | Lumbar Spinal Stenosis | 1 |
| Franklin Avenue Primary Care Center | Suicidal Ideation, Suicide Prevention, Suicide, Attempted | 1 |
| Interventional Pain Consultants | Chronic Pain | 1 |
| Kymera Investigative Site | Eosinophilic Asthma | 1 |
Active & Upcoming Studies in Toledo (2026)
Recruiting trials in Toledo grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (68 active studies)
- Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer · Phase 3 · NRG Oncology
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Neurology & pain (13 active studies)
- Emergent Large Vessel Occlusion Endovascular Rescue Therapy With Underlying Intracranial Stenosis · Phase 3 · ProMedica Health System
- Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy (ALLY) II Trial · Phase 2, Phase 3 · ProMedica Health System
Cardiovascular (12 active studies)
Mental health & behavior (2 active studies)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
- Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program · Phase 3 · Alliance for Clinical Trials in Oncology
Common conditions studied in Toledo
- Asthma (8 active studies). Asthma research tests biologic therapies targeting IL-4, IL-5, and TSLP pathways for moderate-to-severe and eosinophilic disease.
- Heart Failure (6 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- ARDS (4 active studies). Recruiting ARDS studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- ARDS (Acute Respiratory Distress Syndrome) (4 active studies). Recruiting ARDS (Acute Respiratory Distress Syndrome) studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Ischemic Stroke (4 active studies). Stroke trials test acute reperfusion strategies, neuroprotective agents, and rehabilitation technologies to improve recovery.
- Acute Respiratory Distress Syndrome (4 active studies). Recruiting Acute Respiratory Distress Syndrome studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Toledo
- National Cancer Institute (NCI)
- Children's Oncology Group
- NRG Oncology
- SWOG Cancer Research Network
- AstraZeneca
Local regulations and guidelines
Clinical trials in Ohio are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Ohio research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Toledo. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Toledo
Hipa.ai aggregates every recruiting study in Toledo from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Toledo?
There are approximately 156 recruiting clinical trials in Toledo, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Toledo pay participants?
Most recruiting trials in Toledo compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Toledo?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Toledo?
The most common conditions under active study in Toledo include Asthma (8), Heart Failure (6), ARDS (4), ARDS (Acute Respiratory Distress Syndrome) (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Toledo?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Toledo on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Toledo?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Toledo?
Recruiting research sites in Toledo include Mercy Health - Saint Anne Hospital, ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Mercy Health - Saint Vincent Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Toledo right now?
The largest active categories in Toledo are Cancer & tumors (68), Neurology & pain (13), Cardiovascular (12). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.