Paid Clinical Trials in Tennessee

Tennessee has 2,157 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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2,157 clinical trials

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Rare and Atypical Diabetes Network

for Diabetes Mellitus

13 locations incl. Aurora

Sponsor: University of South Florida

Sex: All·Age: All ages

Code: NCT05544266·Recruiting

Apply to this trial

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

for Buccal Mucosa Squamous Cell Carcinoma

105 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT04333537·Phase 2, Phase 3·Recruiting

Apply to this trial

Pancreatic Cancer Early Detection Consortium

for Pancreas Cancer

45 locations incl. Phoenix

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04970056·Recruiting

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A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

for Dravet Syndrome

31 locations incl. Birmingham

Sponsor: Epygenix

Sex: All·Age: 2+

Code: NCT04462770·Phase 3·Recruiting

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Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

for Brain Tumor, Recurrent

54 locations incl. Phoenix

Sponsor: GT Medical Technologies, Inc.

Sex: All·Age: All ages

Code: NCT04427384·Recruiting

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Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase

for Acute Pancreatitis

3 locations incl. Charlotte

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04195347·Phase 1, Phase 2·Recruiting

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A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

539 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

102 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting

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Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure

for Supine Hypertension

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 85

Code: NCT04502225·Recruiting

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Pathways of Eicosanoid Metabolism

for Metabolism of Prostaglandin D2

1 location in Nashville

Sponsor: Vanderbilt University

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT04464070·EARLY_Phase 1·Enrolling By Invitation

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

for Advanced Malignant Neoplasm

4 locations incl. Los Angeles

Sponsor: AtlasMedx, Incorporated

Sex: All·Age: 18+

Code: NCT04503265·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types

for Solid Tumor

24 locations incl. Tucson

Sponsor: Eisai Inc.

Sex: All·Age: 18+

Code: NCT04300556·Phase 1, Phase 2·Recruiting

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Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)

for AVB - Atrioventricular Block

23 locations incl. Phoenix

Sponsor: NYU Langone Health

Sex: Female·Age: 18+

Code: NCT04474223·Phase 3·Recruiting

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CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)

for AML/MDS

2 locations incl. Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04318678·Phase 1·Recruiting

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HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants

for Hydrocephalus

18 locations incl. Birmingham

Sponsor: University of Utah

Sex: All·Age: 1 Day - 104 Weeks

Code: NCT04177914·Phase 3·Recruiting

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

185 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting

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Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

for Breast Cancer

15 locations incl. Stamford

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04468061·Phase 2·Recruiting

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TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

for Cancer

41 locations incl. Tucson

Sponsor: Tizona Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT04485013·Phase 1·Recruiting

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Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

for Breast Cancer

Drug: Atezolizumab

7 locations incl. San Francisco

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04434040·Phase 2·Recruiting

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Impact of Sinus Surgery on Individuals With Cystic Fibrosis

for Chronic Rhinosinusitis (Diagnosis)

9 locations incl. Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 99

Code: NCT04469439·Recruiting

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Predicting the Quality of Response to Specific Treatments in Patients With cGVHD, PQRST Study

for Chronic Graft Versus Host Disease

9 locations incl. Gainesville

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT04431479·Recruiting

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Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

for Pancreatic Neoplasm

408 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 50 - 75

Code: NCT04239573·Recruiting

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

1149 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting

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HEALEY ALS Platform Trial - Master Protocol

for Amyotrophic Lateral Sclerosis

81 locations incl. Phoenix

Sponsor: Merit E. Cudkowicz, MD

Sex: All·Age: 18+

Code: NCT04297683·Phase 2, Phase 3·Recruiting

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A Study of Sigvotatug Vedotin in Advanced Solid Tumors

for Carcinoma, Non-Small Cell Lung

Drug: sigvotatug vedotin

105 locations incl. Anchorage

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT04389632·Phase 1·Recruiting

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Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

for Metastatic Small Intestinal Adenocarcinoma

536 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04205968·Phase 2·Recruiting

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Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

for Head and Neck Squamous Cell Carcinoma

15 locations incl. La Jolla

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT04429542·Phase 1·Recruiting

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Osimertinib Alone or With Chemotherapy for EGFR-Mutant Lung Cancers

for Metastatic Non-small Cell Lung Cancer

Drug: Osimertinib

18 locations incl. Sacramento

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT04410796·Phase 2·Recruiting

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Theophylline for Treatment of Pseudohypoparathyroidism

for Pseudohypoparathyroidism

1 location in Nashville

Sponsor: Jaclyn Tamaroff

Sex: All·Age: 2 - 99·Accepts healthy volunteers

Code: NCT04240821·Phase 2·Enrolling By Invitation

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

for Myelodysplastic Syndromes

Drug: Venetoclax

24 locations incl. Los Angeles

Sponsor: Taiho Oncology, Inc.

Sex: All·Age: 18+

Code: NCT04256317·Phase 2, Phase 3·Recruiting

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Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body

for Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion

51 locations incl. Mesa

Sponsor: Bayer

Sex: All·Age: All ages

Code: NCT04142437·Recruiting

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A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

for Locally Advanced Solid Tumors

Drug: Repotrectinib

20 locations incl. Los Angeles

Sponsor: Turning Point Therapeutics, Inc.

Sex: All·Age: Up to 25

Code: NCT04094610·Phase 1, Phase 2·Recruiting

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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

for Coronavirus Infection (COVID-19)

49 locations incl. Phoenix

Sponsor: Duke University

Sex: All·Age: 0 - 20·Accepts healthy volunteers

Code: NCT04278404·Recruiting

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Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Prostate Cancer

25 locations incl. Duarte

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT04221542·Phase 1·Recruiting

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ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

for Frontotemporal Lobar Degeneration (FTLD)

25 locations incl. Birmingham

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04363684·Recruiting

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Global Utilization And Registry Database for Improved heArt preservatioN

for Heart Diseases

17 locations incl. Stanford

Sponsor: Paragonix Technologies

Sex: All·Age: All ages

Code: NCT04141605·Enrolling By Invitation

Indocyanine Green (ICG) Guided Tumor Resection

for Neoplastic Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT04084067·Phase 1·Recruiting

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[18F]F-DOPA Imaging in Patients With Autonomic Failure

for Autonomic Failure

1 location in Nashville

Sponsor: Daniel Claassen

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04246437·Phase 1·Recruiting

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A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for Low Grade Astrocytoma

Drug: Selumetinib

124 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 - 21

Code: NCT04166409·Phase 3·Recruiting

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

187 locations incl. Birmingham

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting

Apply to this trial