Paid Clinical Trials in Tennessee

Tennessee has 2,155 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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2,155 clinical trials

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Dermal Allograft Augmentation of Large and Massive Rotator Cuff Tears

for Full-thickness Rotator Cuff Tear

4 locations incl. Scottsdale

Sponsor: Arthrex, Inc.

Sex: All·Age: 30 - 75

Code: NCT05981833·Recruiting

Apply to this trial

Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT

for Microtia

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 89

Code: NCT05288790·Phase 2·Recruiting

Apply to this trial

Gene Therapy Trial for Otoferlin Gene-mediated Hearing Loss

for Sensorineural Hearing Loss, Bilateral

6 locations incl. San Francisco

Sponsor: Akouos, Inc.

Sex: All·Age: All ages

Code: NCT05821959·Phase 1, Phase 2·Recruiting

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

955 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting

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Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

for Non-muscle Invasive Bladder Cancer

40 locations incl. Homewood

Sponsor: Protara Therapeutics

Sex: All·Age: 18+

Code: NCT05951179·Phase 2·Recruiting

Apply to this trial

IKS014 in Advanced Solid Tumors That Express HER2

for Breast Cancer

4 locations incl. Newport Beach

Sponsor: Iksuda Therapeutics Ltd.

Sex: All·Age: 18+

Code: NCT05872295·Phase 1·Recruiting

Apply to this trial

Study of VIP943 in Subjects With Advanced CD123+ Hematologic Malignancies

for Acute Myeloid Leukemia

5 locations incl. Birmingham

Sponsor: Vincerx Pharma, Inc.

Sex: All·Age: 18+

Code: NCT06034275·Phase 1·Recruiting

Apply to this trial

Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea

for Obstructive Sleep Apnea of Adult

9 locations incl. Aurora

Sponsor: Cryosa, Inc.

Sex: All·Age: 22 - 70

Code: NCT06008626·Recruiting

Apply to this trial

Cryoablation for Monomorphic Ventricular Tachycardia

for Sustained VT

13 locations incl. Phoenix

Sponsor: Adagio Medical

Sex: All·Age: 18+

Code: NCT05675865·Recruiting

Apply to this trial

Information Processing Biases in Adults Who Stutter

for Stuttering, Adult

1 location in Memphis

Sponsor: University of Memphis

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06422442·Recruiting

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Biomarker-Led Optimization of Successful Surgical Outcomes in Moyamoya

for Moyamoya Disease

2 locations incl. Baltimore

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 69·Accepts healthy volunteers

Code: NCT06634004·Enrolling By Invitation

Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)

for Community-acquired Pneumonia

19 locations incl. Mobile

Sponsor: Biotest

Sex: All·Age: 18+

Code: NCT05722938·Phase 3·Recruiting

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Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD

for Chronic Kidney Diseases

2 locations incl. Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 21 - 85

Code: NCT04984226·Phase 2·Recruiting

Apply to this trial

Assessment of the Ocular Microbiome in Health and Disease

for Microbial Colonization

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05414994·Recruiting

Apply to this trial

Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase

for Alzheimer Disease

3 locations incl. Lakewood

Sponsor: University of Alabama, Tuscaloosa

Sex: All·Age: 50+

Code: NCT05820919·Recruiting

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To Compare the Efficacy and Safety of the ATEV With AVF in Female Patients With End-Stage Renal Disease Requiring Hemodialysis

for End Stage Renal Disease (ESRD)

32 locations incl. Scottsdale

Sponsor: Humacyte, Inc.

Sex: Female·Age: 18+

Code: NCT05908084·Phase 3·Recruiting

Apply to this trial

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

for Non-small Cell Lung Cancer (NSCLC)

17 locations incl. Sacramento

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06040541·Phase 1·Recruiting

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Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

for Primary Biliary Cholangitis

49 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06051617·Phase 3·Recruiting

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The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function

for Obesity

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT05972564·Phase 1, Phase 2·Recruiting

Apply to this trial

A Patient-centered Trial of a Process-of-care Intervention in Hospitalized AKI Patients: the COPE-AKI Trial

for Acute Kidney Injury

9 locations incl. Birmingham

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT05805709·Recruiting

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A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary Cholangitis

for Primary Biliary Cholangitis (PBC)

Drug: Elafibranor

40 locations incl. Tucson

Sponsor: Ipsen

Sex: All·Age: 18+

Code: NCT06016842·Phase 3·Recruiting

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Long-term Follow-up Study of Male Adults With Hemophilia B Previously Treated With Etranacogene Dezaparvovec (CSL222)

for Hemophilia B

15 locations incl. Phoenix

Sponsor: CSL Behring

Sex: Male·Age: 18+

Code: NCT05962398·Enrolling By Invitation

A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

for Frontotemporal Dementia

3 locations incl. Columbus

Sponsor: AviadoBio Ltd

Sex: All·Age: 30 - 75

Code: NCT06064890·Phase 1, Phase 2·Recruiting

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A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

for Advanced Urothelial Carcinoma

12 locations incl. San Francisco

Sponsor: Flare Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT05929235·Phase 1·Recruiting

Apply to this trial

Responding With Evidence and Access for Childhood Headaches

for Headache

15 locations incl. Birmingham

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 10 - 17

Code: NCT05889624·Recruiting

Apply to this trial

Evaluating 111In Panitumumab for Nodal Staging in Head and Neck Cancer

for Head and Neck Squamous Cell Carcinoma

1 location in Nashville

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: 19+

Code: NCT05901545·Phase 1·Recruiting

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A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis

for Atopic Dermatitis

Drug: PF-07275315

52 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT05995964·Phase 2·Recruiting

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Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer

for Nasolacrimal Duct Obstruction

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05999630·Phase 3·Recruiting

Apply to this trial

A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

for Cardiovascular Disorder

31 locations incl. Mobile

Sponsor: Children's Oncology Group

Sex: All·Age: 7+

Code: NCT05705531·Recruiting

Apply to this trial

A Study of DB-1310 in Advanced/Metastatic Solid Tumors

for Advanced Solid Tumor

15 locations incl. Sacramento

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT05785741·Phase 1, Phase 2·Recruiting

Apply to this trial

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

for Advanced Solid Tumors

28 locations incl. Tucson

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT05914116·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED

for Persistent Corneal Epithelial Defect

21 locations incl. Dothan

Sponsor: Glaukos Corporation

Sex: All·Age: 2+

Code: NCT05966493·Phase 2·Recruiting

Apply to this trial

A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

for Uterine Fibroids

Drug: Relugolix

120 locations incl. Mobile

Sponsor: Sumitomo Pharma Switzerland GmbH

Sex: Female·Age: 18 - 50

Code: NCT05862272·Phase 3·Recruiting

Apply to this trial

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

for Non Small Cell Lung Cancer

24 locations incl. Beverly Hills

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT05983432·Phase 1·Recruiting

Apply to this trial

Circulating Tumor DNA to Guide Changes in Standard of Care Chemotherapy

for Metastatic HER2-Negative Breast Carcinoma

1 location in Nashville

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: 18+

Code: NCT05770531·Phase 2·Recruiting

Apply to this trial

Writing Intervention With Adolescents and Young Adults With Cancer

for Cancer Patients

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 15 - 25

Code: NCT05975333·Recruiting

Apply to this trial

Haplo-identical Viral-Specific T-cells for Treatment of Cytomegalovirus and Adenovirus Infections After Hematopoietic Cell Transplantation

for Cytomegalovirus

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 18

Code: NCT05664126·Phase 2·Recruiting

Apply to this trial

Polyethylene-glycol Assisted Nerve Repair in Phalloplasty

for Gender Dysphoria

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Female·Age: 18+

Code: NCT05897086·Phase 2, Phase 3·Enrolling By Invitation

Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease

for cGVHD

32 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT05919511·Recruiting

Apply to this trial

A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.

for Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations

18 locations incl. Birmingham

Sponsor: Taiho Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05967689·Phase 2·Recruiting

Apply to this trial