Paid Clinical Trials in South Carolina

South Carolina has 1,276 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,276 clinical trials

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Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)

for Smell Dysfunction

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65

Code: NCT05855369·Phase 2, Phase 3·Recruiting

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A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors

for Advanced Solid Tumor

4 locations incl. Port Saint Lucie

Sponsor: FBD Biologics Limited

Sex: All·Age: 18+

Code: NCT05892718·Phase 1·Recruiting

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Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T

for Metastatic Castration-Resistant Prostate Cancer (mCRPC)

31 locations incl. Tuscon

Sponsor: Dendreon

Sex: Male·Age: 18+

Code: NCT06134232·Phase 2·Recruiting

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Pulse Endovascular ReperFUSION for Acute Ischemic Stroke

for Acute Ischemic Stroke AIS

1 location in Columbia

Sponsor: Euphrates Vascular, Inc.

Sex: All·Age: 18 - 85

Code: NCT06052969·Recruiting

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Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment

for Grade 3b Follicular Lymphoma

104 locations incl. Tucson

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05890352·Phase 2·Recruiting

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Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure

for Heart Failure

7 locations incl. Palm Springs

Sponsor: Analog Device, Inc.

Sex: All·Age: 18+

Code: NCT05650541·Recruiting

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

955 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting

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Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

for Non-muscle Invasive Bladder Cancer

40 locations incl. Homewood

Sponsor: Protara Therapeutics

Sex: All·Age: 18+

Code: NCT05951179·Phase 2·Recruiting

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Mindfulness Intervention for College Students With ADHD

for Attention Deficit Hyperactivity Disorder

2 locations incl. Tuscaloosa

Sponsor: University of Alabama, Tuscaloosa

Sex: All·Age: 17 - 25

Code: NCT06076967·Recruiting

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Left vs Left Randomized Clinical Trial

for Heart Failure

57 locations incl. Gilbert

Sponsor: Baylor College of Medicine

Sex: All·Age: 18+

Code: NCT05650658·Recruiting

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A Multicenter, Postmarket Surveillance Study of Subjects With the Canary canturioTM te Tibial Extension

for Knee Osteoarthritis

7 locations incl. Fayetteville

Sponsor: Canary Medical

Sex: All·Age: 18+

Code: NCT06040827·Recruiting

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Cryoablation for Monomorphic Ventricular Tachycardia

for Sustained VT

13 locations incl. Phoenix

Sponsor: Adagio Medical

Sex: All·Age: 18+

Code: NCT05675865·Recruiting

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Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

for Primary Biliary Cholangitis

49 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06051617·Phase 3·Recruiting

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A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary Cholangitis

for Primary Biliary Cholangitis (PBC)

Drug: Elafibranor

40 locations incl. Tucson

Sponsor: Ipsen

Sex: All·Age: 18+

Code: NCT06016842·Phase 3·Recruiting

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Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students

for Mental Health Issue

3 locations incl. Columbia

Sponsor: University of Virginia

Sex: All·Age: 10 - 99·Accepts healthy volunteers

Code: NCT06047041·Recruiting

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US National OCS Heart Perfusion (OHP) Registry

for Heart Transplant

37 locations incl. Phoenix

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05915299·Recruiting

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A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma

for Asthma

30 locations incl. Montgomery

Sponsor: AstraZeneca

Sex: All·Age: 5 - 11

Code: NCT06023589·Phase 3·Recruiting

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Operant Conditioning of Spinal Reflexes Training System--Reflex Operant Down Conditioning

for Spinal Cord Injuries

2 locations incl. Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05094362·Recruiting

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Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

for Heart Failure

47 locations incl. Phoenix

Sponsor: Procyrion

Sex: All·Age: 21+

Code: NCT05677100·Recruiting

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The SNAP Tool for Head and Neck Cancer Survivor-Caregiver Dyads

for Head and Neck Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05811936·Recruiting

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A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis

for Atopic Dermatitis

Drug: PF-07275315

52 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT05995964·Phase 2·Recruiting

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Bone-Lead Level Associations With Brain and Mental Health

for Lead Exposure

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT05887934·Enrolling By Invitation

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

for Advanced Solid Tumors

28 locations incl. Tucson

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT05914116·Phase 1, Phase 2·Recruiting

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A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

for Uterine Fibroids

Drug: Relugolix

120 locations incl. Mobile

Sponsor: Sumitomo Pharma Switzerland GmbH

Sex: Female·Age: 18 - 50

Code: NCT05862272·Phase 3·Recruiting

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Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

for Non Small Cell Lung Cancer

24 locations incl. Beverly Hills

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT05983432·Phase 1·Recruiting

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A Long-Term Safety Trial of LUM-201 in Children With Idiopathic Growth Hormone Deficiency Who Have Previously Completed a LUM-201 Clinical Trial (OraGrowtH211)

for Growth Hormone Deficiency

6 locations incl. Iowa City

Sponsor: Lumos Pharma

Sex: All·Age: 5 - 14

Code: NCT05796440·Phase 2·Enrolling By Invitation

Usability of the Adapted Rower for People With Spinal Cord Injury

for Spinal Cord Injuries

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 18+

Code: NCT05959837·Recruiting

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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

40 locations incl. Birmingham

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

93 locations incl. Phoenix

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting

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Encore PFO Closure Device - The PerFOrm Trial

for Patent Foramen Ovale

8 locations incl. Little Rock

Sponsor: Encore Medical Inc.

Sex: All·Age: 18 - 60

Code: NCT05537753·Recruiting

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Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for Locally Advanced Lung Non-Small Cell Carcinoma

470 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05624996·Phase 3·Recruiting

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A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer

for Non-muscle-invasive Bladder Cancer

20 locations incl. Mesa

Sponsor: SURGE Therapeutics

Sex: All·Age: 18+

Code: NCT05710848·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Inadequately Controlled Moderate to Severe Asthma

for Moderate to Severe Asthma

Drug: Povorcitinib

26 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18 - 65

Code: NCT05851443·Phase 2·Recruiting

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Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

for Psychosis Associated With Alzheimer's Disease

Drug: KarXT

147 locations incl. Homewood

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 55 - 90

Code: NCT05980949·Phase 3·Recruiting

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EMPOWER: Effects of Weight Loss and Exercise Post-stroke

for Obesity

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 35 - 85

Code: NCT05901675·Recruiting

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A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

for Chronic Obstructive Pulmonary Disease

68 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 40 - 90

Code: NCT05878769·Phase 3·Recruiting

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A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

for Hidradenitis Suppurativa

Drug: Upadacitinib

87 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 12+

Code: NCT05889182·Phase 3·Recruiting

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Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

for Anatomic Stage II Breast Cancer AJCC v8

820 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05812807·Phase 3·Recruiting

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A Dose Escalation Study of AV-380 in Cancer Patients With Cachexia

for Cachexia

12 locations incl. Beverly Hills

Sponsor: AVEO Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05865535·Phase 1·Recruiting

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Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab

for Relapsing Multiple Sclerosis

36 locations incl. Birmingham

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT05877963·Phase 3·Recruiting

Apply to this trial