Paid Clinical Trials in South Carolina

South Carolina has 1,276 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,276 clinical trials

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Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

for Diffuse Large B-Cell Lymphoma

87 locations incl. Tucson

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05633615·Phase 2·Recruiting

Apply to this trial

Alzheimer's Disease Neuroimaging Initiative 4

for Mild Cognitive Impairment

59 locations incl. Birmingham

Sponsor: University of Southern California

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05617014·Enrolling By Invitation

Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy

for Malignant Solid Neoplasm

36 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642611·Phase 3·Recruiting

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Study of Effect of Azeliragon in Patients Refractory to Prior Treatment of Metastatic Pancreatic Cancer

for Metastatic Pancreatic Cancer

6 locations incl. Los Angeles

Sponsor: Cantex Pharmaceuticals

Sex: All·Age: 18 - 80

Code: NCT05766748·Phase 1, Phase 2·Recruiting

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Precision Rehabilitation for Veterans With (HFpEF)

for Heart Failure

1 location in Columbia

Sponsor: Columbia VA Health Care System

Sex: All·Age: 18+

Code: NCT07493915·Recruiting

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Pragmatic Trial to Enhance Quality Safety, and Patient Experience in COPD

for Pulmonary Disease, Chronic Obstructive

5 locations incl. Minneapolis

Sponsor: Seattle Institute for Biomedical and Clinical Research

Sex: All·Age: All ages

Code: NCT05718102·Recruiting

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A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Drug: Nivolumab

390 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 5 - 60

Code: NCT05675410·Phase 3·Recruiting

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A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation

for Heart Failure

Drug: Ziltivekimab

184 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT05636176·Phase 3·Recruiting

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Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

454 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642572·Phase 2·Recruiting

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Platform of Randomized Adaptive Clinical Trials in Critical Illness

for Respiratory Insufficiency

26 locations incl. Tucson

Sponsor: University Health Network, Toronto

Sex: All·Age: 18+

Code: NCT05440851·Recruiting

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A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma

for Asthma

28 locations incl. Birmingham

Sponsor: GlaxoSmithKline

Sex: All·Age: 12 - 17

Code: NCT05757102·Phase 3·Recruiting

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Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for Cystic Fibrosis

59 locations incl. Birmingham

Sponsor: Chris Goss

Sex: All·Age: 6+

Code: NCT05548283·Phase 4·Recruiting

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Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)

for Tachycardia, Ventricular

11 locations incl. Los Angeles

Sponsor: Varian, a Siemens Healthineers Company

Sex: All·Age: 18+

Code: NCT05765175·Recruiting

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Pounce™ Thrombectomy System Retrospective Registry

for Peripheral Arterial Disease

9 locations incl. Peoria

Sponsor: SurModics, Inc.

Sex: All·Age: 18+

Code: NCT05868161·Recruiting

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Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury

for Acute Kidney Injury

38 locations incl. Birmingham

Sponsor: SeaStar Medical

Sex: All·Age: 18+

Code: NCT05758077·Recruiting

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Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant

for Pre-Bronchiolitis Obliterans Syndrome

20 locations incl. Phoenix

Sponsor: Renovion, Inc.

Sex: All·Age: 18 - 75

Code: NCT05654922·Phase 3·Recruiting

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

475 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting

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A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)

for Asthma

28 locations incl. Mobile

Sponsor: AstraZeneca

Sex: All·Age: 6 - 18

Code: NCT05692180·Phase 3·Recruiting

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A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions

for Narcolepsy Type 1

19 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 16 - 70

Code: NCT05816382·Phase 2, Phase 3·Recruiting

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Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

for Prediabetic State

40 locations incl. Phoenix

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT02915198·Phase 4·Recruiting

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Cognitive Decline Following Deep Brain Stimulation

for Parkinson Disease

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05822388·Recruiting

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A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

for Breast Cancer, Early Breast Cancer

Drug: Camizestrant

129 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT05774951·Phase 3·Recruiting

Apply to this trial

Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI

for Spinal Cord Injuries

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05492188·Recruiting

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RM1 Project 1 - tAN Naloxone

for Analgesia

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05490134·EARLY_Phase 1·Recruiting

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A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin

for Growth Hormone Deficiency

27 locations incl. Phoenix

Sponsor: Ascendis Pharma Endocrinology Division A/S

Sex: All·Age: 1 - 18

Code: NCT05775523·Recruiting

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A US Non-interventional, Effectiveness and Safety Study of Patients Treated With SKYTROFA

for Growth Hormone Deficiency

27 locations incl. Phoenix

Sponsor: Ascendis Pharma Endocrinology Division A/S

Sex: All·Age: All ages

Code: NCT05820672·Recruiting

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RM1 Project 2 - tAN fMRI

for Auricular Stimulation

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05487664·Recruiting

Apply to this trial

Pancreatic Cancer Detection Consortium

for Pancreatic Cancer

9 locations incl. Phoenix

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06388967·Recruiting

Apply to this trial

taVNS or TMS or Both for Depression

for Depression

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 75

Code: NCT05725239·Recruiting

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Brief Family Involved Treatment Telehealth

for Alcohol Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+

Code: NCT05674409·Recruiting

Apply to this trial

A Study of ASP1002 in Adults for Treatment of Solid Tumors

for Advanced Solid Tumors

15 locations incl. New Haven

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT05719558·Phase 1·Recruiting

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A Study of BLB-201 RSV Vaccine in Infants and Children

for Respiratory Syncytial Virus Infections

15 locations incl. La Mesa

Sponsor: Blue Lake Biotechnology Inc.

Sex: All·Age: 6 Months - 5·Accepts healthy volunteers

Code: NCT05655182·Phase 1, Phase 2·Recruiting

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A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

for Atopic Dermatitis

21 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 Months - 18

Code: NCT05735483·Phase 3·Enrolling By Invitation

Investigating Novel Smoking Cessation Primary Care Interventions in Rural Environments

for Smoking Cessation

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05764759·Recruiting

Apply to this trial

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for Alpha1-Antitrypsin Deficiency

37 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT05677971·Phase 3·Recruiting

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Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

for Metastatic Salivary Gland Carcinoma

150 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05408845·Phase 2·Recruiting

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A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

for High Grade Osteosarcoma

Drug: Cabozantinib

175 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 40

Code: NCT05691478·Phase 2, Phase 3·Recruiting

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A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

for Areata Alopecia

Drug: Baricitinib

44 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 - 17

Code: NCT05723198·Phase 3·Recruiting

Apply to this trial

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for Childhood Medulloblastoma

101 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 4 - 21

Code: NCT05382338·Phase 3·Recruiting

Apply to this trial

Safety Study of Tenapanor for the Treatment of Pediatric Patients (6 to Less Than 18 Years Old) With IBS-C

for Irritable Bowel Syndrome With Constipation (IBS-C)

Drug: Tenapanor

27 locations incl. Foley

Sponsor: Ardelyx

Sex: All·Age: 6 - 18

Code: NCT05905926·Phase 3·Enrolling By Invitation