Paid Clinical Trials in North Carolina

North Carolina has 2,944 paid clinical trials enrolling now across cities including Durham, Chapel Hill and Winston-Salem. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in North Carolina include Duke University Medical Center, UNC Health and Wake Forest Baptist, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,944 clinical trials

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Pharmacokinetics of Drugs Administered to Children

for Pediatric ALL

1 location in Durham

Sponsor: Duke University

Sex: All·Age: 0 - 20

Code: NCT03481881·Recruiting

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Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

for Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma

Drug: Atezolizumab

338 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT01810913·Phase 2, Phase 3·Recruiting

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Atypical Hemolytic-Uremic Syndrome (aHUS) Registry

for Atypical Hemolytic-Uremic Syndrome

9 locations incl. Aurora

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: All ages

Code: NCT01522183·Recruiting

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Tracking Results of Ablations to Combat AF Registry Generation 2

for Atrial Fibrillation

26 locations incl. Huntsville

Sponsor: AtriCure, Inc.

Sex: All·Age: 18+

Code: NCT05111015·Recruiting

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Multi-Center Registry for Peripheral Arterial Disease Interventions and Outcomes

for Peripheral Arterial Disease

24 locations incl. Little Rock

Sponsor: Baylor Research Institute

Sex: All·Age: All ages

Code: NCT01904851·Recruiting

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Proton or Photon RT for Retroperitoneal Sarcomas

for Retroperitoneal Sarcoma

10 locations incl. Chicago

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT01659203·Phase 1, Phase 2·Recruiting

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RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain

for Pain

67 locations incl. Phoenix

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT01719055·Recruiting

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Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease

for Legg Calve Perthes Disease

28 locations incl. Birmingham

Sponsor: Texas Scottish Rite Hospital for Children

Sex: All·Age: 1 - 18

Code: NCT02040714·Enrolling By Invitation

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

for Huntington's Disease

62 locations incl. Birmingham

Sponsor: CHDI Foundation, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01574053·Recruiting

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Evaluation of Visceral Function Following Endovascular Aortic Aneurysm Repair Using Branched Stent- Grafts

for Aortic Aneurysm, Abdominal

1 location in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18+

Code: NCT01654133·Enrolling By Invitation

Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

for Pediatric Patients Treated With Radiation Therapy

24 locations incl. Palo Alto

Sponsor: Massachusetts General Hospital

Sex: All·Age: Up to 21

Code: NCT01696721·Recruiting

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Study of the Effect of Innate on the Inflammatory Response to Endotoxin

for Asthma

1 location in Research Triangle Park

Sponsor: National Institute of Environmental Health Sciences (NIEHS)

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT01143480·Recruiting

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Facial Analysis to Classify Difficult Intubation

for Difficult Intubation

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT01612949·Recruiting

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Inherited Reproductive Disorders

for Genetic Disorder

2 locations incl. Bethesda

Sponsor: National Institute of Environmental Health Sciences (NIEHS)

Sex: All·Age: 6 Weeks - 120

Code: NCT01500447·Recruiting

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Patient Retrospective Outcomes (PRO)

for Chronic Pain

87 locations incl. Lake Havasu City

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT01550575·Recruiting

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Product Surveillance Registry

for Cardiac Rhythm Disorders

134 locations incl. Birmingham

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT01524276·Recruiting

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

142 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting

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Functional Assessment in Liver Transplantation

for End Stage Liver Disease

12 locations incl. Little Rock

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT03228290·Recruiting

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Neuroblastoma Biology Study

for Neuroblastoma

16 locations incl. Los Angeles

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 31 Days - 99

Code: NCT01587300·Recruiting

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Environmental Risk Factors for the Anti-synthetase Syndrome

for Myositis

8 locations incl. Miami

Sponsor: National Institute of Environmental Health Sciences (NIEHS)

Sex: All·Age: 2 - 100·Accepts healthy volunteers

Code: NCT01276470·Recruiting

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Hyperpolarized 129Xe MRI for Imaging Pulmonary Function

for Interstitial Lung Disease

1 location in Durham

Sponsor: Bastiaan Driehuys

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01280994·Phase 2·Recruiting

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Longitudinal Study of the Porphyrias

for Acute Porphyrias

16 locations incl. Birmingham

Sponsor: The American Porphyrias Expert Collaborative

Sex: All·Age: 1 Minute+

Code: NCT01561157·Recruiting

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Natural History Study of SCID Disorders

for Severe Combined Immunodeficiency (SCID)

39 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: All ages

Code: NCT01186913·Enrolling By Invitation

Pharmacokinetics of Off Label Pediatric Medications

for Off Label Use of Medications in Pediatric Patients

1 location in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 1 Day - 8

Code: NCT01286519·Recruiting

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Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

for Charcot-Marie-Tooth Disease, Type Ia (Disorder)

17 locations incl. Los Angeles

Sponsor: University of Iowa

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01193088·Recruiting

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Personalized Environment and Genes Study

for Diabetes

2 locations incl. Chapel Hill

Sponsor: National Institute of Environmental Health Sciences (NIEHS)

Sex: All·Age: 18 - 120·Accepts healthy volunteers

Code: NCT00341237·Recruiting

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Nephrotic Syndrome Study Network

for Minimal Change Disease (MCD)

39 locations incl. Los Angeles

Sponsor: University of Michigan

Sex: All·Age: Up to 80

Code: NCT01209000·Recruiting

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Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

for Sarcoma

5 locations incl. Washington D.C.

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 4 Weeks+·Accepts healthy volunteers

Code: NCT01109394·Recruiting

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Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

for Failed or Difficult Intubation, Sequela

63 locations incl. Birmingham

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT02493478·Recruiting

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I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for Breast Neoplasms

42 locations incl. Birmingham

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT01042379·Phase 2·Recruiting

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Registry of Older Patients With Cancer

for Chronic Myeloproliferative Disorders

7 locations incl. Boone

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 65+

Code: NCT01137825·Recruiting

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Determination of CRIM Status and Longitudinal Follow-up of Individuals With Pompe Disease

for Pompe Disease

1 location in Durham

Sponsor: Duke University

Sex: All·Age: All ages

Code: NCT01665326·Recruiting

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Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility

for Normal and Diseased Tissue and Body Fluids Samples

14 locations incl. Huntsville

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01354002·Recruiting

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Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

for Chronic Myeloproliferative Disorders

1 location in Chapel Hill

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18 - 120

Code: NCT01137643·Recruiting

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Immune Cell Response to Stimuli

for Inflammation

1 location in Research Triangle Park

Sponsor: National Institute of Environmental Health Sciences (NIEHS)

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT00397280·Recruiting

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Registry Study for Radiation Therapy Outcomes

for Neoplasms

29 locations incl. Scottsdale

Sponsor: Proton Collaborative Group

Sex: All·Age: All ages

Code: NCT01255748·Recruiting

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Establishment of Cell Culture Systems From Discarded Operating Room Tissue

for Surgery

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 28 Days - 80

Code: NCT01000077·Enrolling By Invitation

Clinical Phenotyping Resource and Biobank Core of the Michigan O'Brien Renal Center

for Chronic Kidney Disease

5 locations incl. Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01016613·Recruiting

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Prenatal Exposure Effects Psychophysiology Study

for Pregnancy

1 location in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT01134770·Enrolling By Invitation

Maternal Newborn Health Registry

for Pregnancy Outcome Trends in Low-resource Geographic Areas

8 locations incl. Birmingham

Sponsor: NICHD Global Network for Women's and Children's Health

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01073475·Recruiting

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