Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

Part of paid clinical trials in Palo Alto, California.

Sponsor: Massachusetts General Hospital
Study ID: NCT01696721
Status: Recruiting

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Conditions

Pediatric Patients Treated With Radiation Therapy

Eligibility Criteria

Sex: ALL
Age: N/A - 21 Years
Healthy Volunteers: Not accepted

Interventions

No intervention — OTHER

Study Details

In previous studies, Proton Beam Radiation Therapy (PBRT) has been found to show better results in treating patients with cancer, both because there is better control of where in the body the radiation is directed and because it is associated with less severe long term side effects. However, there is limited published data demonstrating these results. The goal of the Proton and Photon Consortium Registry (PPCR) is to enroll children treated with radiation in order to describe the population that currently receives radiation and better compare the short-term and long-term benefits of different types of radiotherapy. The data collected from this study will help facilitate research on radiation therapy and allow for collaborative research. The PPCR will collect demographic and clinical data that many centers that deliver radiation therapy already collect in routine operations.

Key Dates

Start date: Jul 31, 2012
Status verified: May 2026
Primary completion: Dec 31, 2028
Completion: Dec 31, 2028

Study Design

Enrollment: 5,000 participants (estimated)

Arms

Arm: Pediatric Patients Treated with Protons
Proton Radiation Therapy

Primary Outcome Measure

Establish Registry [ Time Frame: 2 years ]

Central Contacts

Torunn I Yock, MD
6177266876
[email protected]

Locations (24)

Facility	City	State	ZIP	Site coordinators
Stanford University	Palo Alto	California	94304	Susan Hiniker, MD [email protected] Susan Hiniker, MD (PRINCIPAL_INVESTIGATOR)
California Protons Cancer Therapy Center	San Diego	California	92121	Iain MacEwan, MD [email protected] Iain MacEwan, MD (PRINCIPAL_INVESTIGATOR)
University of California San Francisco	San Francisco	California	94143	Steve Braunstein, MD [email protected] Steve Braunstein, MD (PRINCIPAL_INVESTIGATOR)
University of Florida Health Proton Therapy Institute	Jacksonville	Florida	32206	Daniel Indelicato, MD [email protected] Daniel Indelicato, MD (PRINCIPAL_INVESTIGATOR)
Emory University	Atlanta	Georgia	30308	Bree Eaton, MD [email protected] Bree Eaton, MD (PRINCIPAL_INVESTIGATOR)
Northwestern Medicine Chicago Proton Center	Warrenville	Illinois	60555	Stephen Mihalcik, MD [email protected] Stephen Mihalcik, MD (PRINCIPAL_INVESTIGATOR)
Maryland Proton Treatment Center	Baltimore	Maryland	21201	Young Kwok, MD [email protected] Young Kwok, MD (PRINCIPAL_INVESTIGATOR)
Massachusetts General Hospital	Boston	Massachusetts	02114	Torunn I Yock, MD [email protected] 617-726-6876 Torunn I Yock, MD (PRINCIPAL_INVESTIGATOR)
Mayo Clinic	Rochester	Minnesota	55905	Nadia Laack, MD [email protected] Nadia Laack, MD (PRINCIPAL_INVESTIGATOR)
Washington University	St Louis	Missouri	63110	Stephanie Perkins, MD [email protected] Stephanie Perkins, MD (PRINCIPAL_INVESTIGATOR)
ProCure Proton Therapy Center- New Jersey	Somerset	New Jersey	08873	Josephine Blume [email protected] Suzanne Wolden, MD (PRINCIPAL_INVESTIGATOR)
New York Proton Center	New York	New York	10035	Suzanne Wolden, MD [email protected] Suzanne Wolden, MD (PRINCIPAL_INVESTIGATOR)
State University of New York Upstate Medical Center	Syracuse	New York	13210	Paul Aridgides, MD [email protected] Paul Aridgides, MD (PRINCIPAL_INVESTIGATOR)
University of North Carolina	Chapel Hill	North Carolina	27514	Dana Casey, MD [email protected] Dana Casey, MD (PRINCIPAL_INVESTIGATOR)
The Ohio State University	Columbus	Ohio	43210	Joshua Palmer, MD [email protected] Joshua Palmer, MD (PRINCIPAL_INVESTIGATOR)
Cincinnati Children's Proton Therapy Center	Liberty Township	Ohio	45044	John Perentesis, MD [email protected] John Perentesis, MD (PRINCIPAL_INVESTIGATOR)
Oklahoma Proton Center	Oklahoma City	Oklahoma	73142	John H Chang, MD [email protected] John H Chang, MD (PRINCIPAL_INVESTIGATOR)
ProCure Proton Therapy Center- Oklahoma	Oklahoma City	Oklahoma	73142	Jae Y Lee, MD, PhD [email protected] Jae Y Lee, MD, PhD (PRINCIPAL_INVESTIGATOR)
University of Pennsylvania - Roberts Proton Therapy Center	Philadelphia	Pennsylvania	19104	Christine Hill-Kayser, MD [email protected] Christine Hill-Kayser, MD (PRINCIPAL_INVESTIGATOR)
Provision Center for Proton Therapy	Knoxville	Tennessee	37909	-
MD Anderson Cancer Center	Houston	Texas	77030	Arnold Paulino, MD [email protected] Arnold Paulino, MD (PRINCIPAL_INVESTIGATOR)
Texas Center for Proton Therapy	Irving	Texas	75063	Victor Mangona, MD [email protected] Victor Mangona, MD (PRINCIPAL_INVESTIGATOR)
University of Utah	Salt Lake City	Utah	84112	Matthew Poppe, MD [email protected] Matthew Poppe, MD (PRINCIPAL_INVESTIGATOR)
University of Washington- Seattle Cancer Care Alliance	Seattle	Washington	98109	Ralph Ermoian, MD [email protected] Ralph Ermoian, MD (PRINCIPAL_INVESTIGATOR)

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Stanford University· Palo Alto, CA California Protons Cancer Therapy Center· San Diego, CA University of California San Francisco· San Francisco, CA University of Florida Health Proton Therapy Institute· Jacksonville, FL Emory University· Atlanta, GA Northwestern Medicine Chicago Proton Center· Warrenville, IL