Paid Clinical Trials in Minnesota

Minnesota has 2,364 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,364 clinical trials

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An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study)

for Guillain-Barre Syndrome

12 locations incl. Phoenix

Sponsor: Annexon, Inc.

Sex: All·Age: 12 - 85

Code: NCT07020819·Phase 3·Recruiting

Apply to this trial

A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma

for Glioma

2 locations incl. Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07074756·Recruiting

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A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

for Breast Neoplasms

46 locations incl. Hot Springs

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06926868·Phase 2, Phase 3·Recruiting

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A Study Of Cryptoglandular Fistula-in-ano And Associated Non-healing Draining Wounds With Kerecis SurgiClose

for Fistula-in-ano

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07098715·Enrolling By Invitation

A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet

for LDL Hyper-responsiveness

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07137286·Recruiting

Apply to this trial

Lumbar & Sacroiliac Fusion Study Involving Previously Implanted Devices

for Fusion of Spine

3 locations incl. Overland Park

Sponsor: Spinal Simplicity LLC

Sex: All·Age: 18+

Code: NCT07204288·Recruiting

Apply to this trial

Gii'Igoshimong: Sitting With Your First Family

for Substance Use

1 location in Duluth

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07075081·Phase 2·Recruiting

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LEgal Guidance and AdvocaCY for CAREgivers (LEGACY CARE): A Pilot Clinical Trial for Caregivers of Persons With Colorectal Cancer

for Caregiver Burden

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07153016·Recruiting

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Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

for Metastatic Clear Cell Renal Cell Carcinoma

Drug: Cabozantinib

40 locations incl. Gilbert

Sponsor: Arcus Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07011719·Phase 3·Recruiting

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Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC

for Hepatocellular Carcinoma (HCC)

13 locations incl. Birmingham

Sponsor: RayzeBio, Inc.

Sex: All·Age: 18+

Code: NCT06726161·Phase 1, Phase 2·Recruiting

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Education & Mentorship of Advanced Practice Providers to Increase Community-based Research Within the NCORP Network, COACH-APP Trial

for Other

31 locations incl. Newark

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06904391·Recruiting

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A Study to Evaluate the Safety and Efficacy of BGB-16673 Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

36 locations incl. Phoenix

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06973187·Phase 3·Recruiting

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A Study Investigating the Impact of IMT With CR On Exercise Responses In HF

for Heart Failure With Reduced Ejection Fraction

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07086131·Recruiting

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Screening and Staging of Benign vs Malignant Pelvic Abnormalities

for Endometrial Carcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07407959·Recruiting

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Post-Approval Study of the Neuspera Sacral Neuromodulation System

for Urinary Urgency Incontinence

20 locations incl. San Diego

Sponsor: Neuspera Medical, Inc.

Sex: All·Age: 22+

Code: NCT07144813·Recruiting

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Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

for Viral Pneumonia

22 locations incl. Sacramento

Sponsor: Synairgen Research Ltd.

Sex: All·Age: 18+

Code: NCT06999603·Phase 2·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

for Colorectal Cancer

22 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07023289·Phase 2·Recruiting

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A Study to Assess How Effective and Safe NVD003 is for Treating Patients With Congenital Pseudarthrosis of the Tibia.

for Congenital Pseudarthrosis of Tibia

4 locations incl. Phoenix

Sponsor: Novadip Biosciences

Sex: All·Age: Up to 17

Code: NCT07112443·Phase 3·Recruiting

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A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

for Metastatic Castration-resistant Prostate Neoplasms

Drug: Pasritamig

50 locations incl. La Jolla

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT07164443·Phase 3·Recruiting

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Effect of Vagal Nerve Stimulation on Gastric Motor Functions

for Depression

2 locations incl. Minneapolis

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06038929·Recruiting

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Cardiac Structure and Function in MPS

for MPS I

3 locations incl. Orange

Sponsor: Children's Hospital of Orange County

Sex: All·Age: 0 - 99·Accepts healthy volunteers

Code: NCT07361536·Recruiting

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Evaluating Patient Reported Outcomes and Surgeon Satisfaction With Ziplyft™

for Blepharoplasty

5 locations incl. Miami

Sponsor: Osheru Inc.

Sex: All·Age: 35+

Code: NCT07144761·Recruiting

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An Optimized Ultrasound Twinkling Marker for the Imaging of Lymph Nodes in Patients With Clinically Node-Positive Breast Cancer, The UTMOST2 Trial

for Anatomic Stage II Breast Cancer AJCC v8

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT06999798·Phase 1·Recruiting

Apply to this trial

Integrating Molecular Pathology, Radiology, and Genetics to Improve Breast Cancer Risk

for Breast Carcinoma

2 locations incl. Jacksonville

Sponsor: Mayo Clinic

Sex: Female·Age: 18 - 100·Accepts healthy volunteers

Code: NCT07207564·Recruiting

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Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

for Neurofibromatosis 1

Drug: Selumetinib

15 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 1 - 8

Code: NCT06188741·Phase 2·Recruiting

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Q702 for the Treatment of Patients With Hematologic Malignancies

for Hematopoietic and Lymphatic System Neoplasm

2 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06712810·Phase 1·Recruiting

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A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

for Advanced Pancreatic Carcinoma

109 locations incl. Birmingham

Sponsor: Sameek Roychowdhury

Sex: All·Age: 18+

Code: NCT06906562·Phase 2·Recruiting

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A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.

for Invasive Mold Infections

15 locations incl. Birmingham

Sponsor: Basilea Pharmaceutica

Sex: All·Age: 18+

Code: NCT06925321·Phase 3·Recruiting

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Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for PIK3CA Mutation

51 locations incl. Gilbert

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06982521·Phase 3·Recruiting

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Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)

for Cannabis Use

1 location in Saint Louis Park

Sponsor: HealthPartners Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07227324·Recruiting

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An International Observational Study of Adults With Acute Infection

for Infectious Disease

18 locations incl. Tucson

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07069400·Recruiting

Apply to this trial

Torque Device Evaluation

for Electrophysiology Study

2 locations incl. Washington D.C.

Sponsor: University of Minnesota

Sex: All·Age: Up to 21

Code: NCT07094256·Recruiting

Apply to this trial

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

for Cardiovascular Disease

Drug: Olpasiran

204 locations incl. Alexander City

Sponsor: Amgen

Sex: All·Age: 50 - 105

Code: NCT07136012·Phase 3·Recruiting

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Evaluation of Microbiota Transplant Therapy in Patients With Alopecia Areata

for Alopecia Areata

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT06747611·Phase 2·Recruiting

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Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

for Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma

279 locations incl. Gilbert

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06958328·Phase 3·Recruiting

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AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions

for Coronary Arterial Disease (CAD)

42 locations incl. La Jolla

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT06959524·Recruiting

Apply to this trial

NAL ER IPF Respiratory Function and Safety Study

for Idiopathic Pulmonary Fibrosis

1 location in Rochester

Sponsor: Trevi Therapeutics

Sex: All·Age: 18+

Code: NCT07036029·Phase 1·Recruiting

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Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV)

for Non-small Cell Lung Cancer (NSCLC)

12 locations incl. Los Angeles

Sponsor: Nuvation Bio Inc.

Sex: All·Age: 18+

Code: NCT07154706·Phase 3·Recruiting

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Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

for Gastric Adenocarcinoma

55 locations incl. Irvine

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT07001748·Phase 2, Phase 3·Recruiting

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Impact of RFA on Esophageal Distensibility and Mucosal Impedance

for Dysplastic Barrett's Esophagus

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07126535·Recruiting

Apply to this trial