Paid Clinical Trials in Minnesota

Minnesota has 2,364 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,364 clinical trials

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A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

for Small-cell Lung Cancer

Drug: Durvalumab

43 locations incl. Casa Grande

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07005128·Phase 3·Recruiting

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Prehabilitation With Aerobic and Resistance Exercise for Improving Physical Fitness and Quality of Life Outcomes in Older Patients Undergoing CAR-T Therapy for Relapsed or Refractory Multiple Myeloma

for Recurrent Multiple Myeloma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 60+

Code: NCT07045727·Recruiting

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A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

for Relapsed AL Amyloidosis

12 locations incl. Phoenix

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07081646·Phase 1, Phase 2·Recruiting

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A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzabrutinib Compared With Placebo in Participants 18 Years of Age and Older With Warm Autoimmune Hemolytic Anemia

for Autoimmune Haemolytic Anaemia

23 locations incl. Phoenix

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07086976·Phase 3·Recruiting

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SMART Therapist Training: A Hybrid Factorial-SMART Design

for Stress Disorders, Post-Traumatic

4 locations incl. Palo Alto

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07010770·Recruiting

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FIBERGRAFT Aeridyan Posterolateral Fusion Study

for Degenerative Spine Disease

8 locations incl. Sacramento

Sponsor: DePuy Synthes Products, Inc.

Sex: All·Age: 18+

Code: NCT07059065·Recruiting

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Sonodynamic Therapy With SONALA-001 or 5-ALA HCL and Magnetic Resonance Guided Focused Ultrasound for the Treatment of Progressive or Recurrent Glioblastoma

for Progressive Glioblastoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07076472·EARLY_Phase 1·Recruiting

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Abbott Cephea Mitral Valve Disease Registry

for Mitral Regurgitation

22 locations incl. Phoenix

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT07069673·Recruiting

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Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the Pouch

for Pouchitis

5 locations incl. Los Angeles

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18 - 80

Code: NCT06864403·Phase 4·Recruiting

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A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)

for Polycythemia Vera (PV)

15 locations incl. Phoenix

Sponsor: Disc Medicine, Inc

Sex: All·Age: 18+

Code: NCT06985147·Phase 2·Recruiting

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Sequential Treatments or Combinations Including Dasatinib, Quercetin, Fisetin and/or Temozolomide for the Treatment of Previously Treated Glioma With Residual Disease

for Glioma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07025226·EARLY_Phase 1·Recruiting

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Ketogenic Intervention for Bipolar Depression

for Bipolar Depression

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 50

Code: NCT07121894·Recruiting

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Choline and Iron Deficiency

for Pediatric Iron Deficiency

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 5 Months - 7 Months

Code: NCT06527391·Phase 2, Phase 3·Recruiting

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The Impact of Biological Mechanisms of Aging on Response Variability to Resistance Training in Older Adults

for Aging

2 locations incl. Boston

Sponsor: Mayo Clinic

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06940037·Recruiting

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AI Assisted Personalized Legacy Program (Reflections: My Story) for Patients With Serious Illness

for Serious Illness

2 locations incl. Phoenix

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07009210·Recruiting

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Minibeam Radiation Therapy With Tungsten Slit Collimator for the Treatment of Recurrent or Metastatic Skin or Soft Tissue Tumors

for Metastatic Malignant Skin Neoplasm

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07062003·Recruiting

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A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes

for Diabetes Mellitus, Type 1

109 locations incl. Cullman

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07076199·Phase 3·Recruiting

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HM2023-43:Ph 2 Trial of Tafasitamab With Lenalidomide+Rituximab in Treatment-naive FL and MZL

for Follicular Lymphoma

Drug: Tafasitamab

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT06792825·Phase 2·Recruiting

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Transcutaneous Spinal Stimulation for Children and Youth With Spina Bifida

for Myelomeningocele

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 5 - 18

Code: NCT06918119·Recruiting

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A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism

for Primary Hyperaldosteronism

Drug: Baxdrostat

21 locations incl. Los Angeles

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07007793·Phase 3·Recruiting

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Acolyte CTO-PCI Study: Imaging and Catheter System to Treat Patients With Coronary Chronic Total Occlusion, Who Have Persistent Symptoms Following Medical Therapy and Are Undergoing Percutaneous Coronary Interventional Procedures

for Coronary Chronic Total Occlusions

5 locations incl. Atlanta

Sponsor: Elumn8 Medical

Sex: All·Age: 18+

Code: NCT06795763·Enrolling By Invitation

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

for Prostate Cancer

Drug: Saruparib

42 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT06952803·Phase 3·Recruiting

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A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

for Type 1 Diabetes Mellitus

32 locations incl. Scottsdale

Sponsor: Sanofi

Sex: All·Age: 1 - 25

Code: NCT07088068·Phase 3·Recruiting

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Study of EN-374 Gene Therapy in Participants With X-Linked Chronic Granulomatous Disease

for X-Linked Chronic Granulomatous Disease

8 locations incl. Los Angeles

Sponsor: Ensoma

Sex: Male·Age: 3 Months+

Code: NCT06876363·Phase 1, Phase 2·Recruiting

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A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

for Breast Cancer

102 locations incl. Chandler

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07062965·Phase 3·Recruiting

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Visual Outcomes in Patients Contralaterally Implanted With PanOptix Pro and Clareon Vivity Compared to Bilateral Implantation of PanOptix Pro

for Cataract

5 locations incl. Baltimore

Sponsor: Brian Shafer

Sex: All·Age: 18+

Code: NCT07076277·Enrolling By Invitation

Fastomics: Metabolic and Therapeutic Effects of Prolonged Fasting

for Insulin Resistance

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07216989·Recruiting

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Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

for Proliferative Diabetic Retinopathy (PDR)

27 locations incl. Huntington Beach

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT06790784·Phase 3·Recruiting

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Surface EMG Testing on Swallowing in EoE Patients

for Eosinophilic Esophagitis (EoE)

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07156357·Recruiting

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Evaluation of Accuracy of the Owlet OSS 3.0 Sensor in the Neonatal Population

for Pulse Oximeter Validation

2 locations incl. Birmingham

Sponsor: Owlet Baby Care, Inc.

Sex: All·Age: 0 Days - 28 Days

Code: NCT06771206·Recruiting

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Study Evaluating the Efficacy and Safety of Artesunate

for CMV Infection

2 locations incl. Boston

Sponsor: Amivas Inc.

Sex: All·Age: 18+

Code: NCT06853184·Phase 2·Recruiting

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Effect of Prolonged Fasting Time on Gastric Residual Volume in Patients Taking GLP1 Receptor Agonists

for Upper Endoscopy

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07006142·Recruiting

Apply to this trial

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

for Endometrial Cancer

68 locations incl. Tucson

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07044336·Phase 3·Recruiting

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Therapeutic Plasma Exchange With Enfortumab Vedotin and Pembrolizumab for Treatment of Bladder Cancers

for Metastatic Bladder Urothelial Carcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07087860·Phase 2·Recruiting

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Irrigating vs Traditional Negative Pressure Wound Therapy to Treat Necrotizing Soft Tissue Infections

for Necrotizing Soft Tissue Infections

1 location in Saint Paul

Sponsor: HealthPartners Institute

Sex: All·Age: 18+

Code: NCT07120386·Recruiting

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A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products

for Solid Tumor Cancer

3 locations incl. Gilbert

Sponsor: A2 Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT06885424·Enrolling By Invitation

A Phase IIb Ensifentrine-glycopyrrolate Fixed-dose Combination Dose Ranging Study in Subjects With COPD

for Chronic Obstructive Pulmonary Disease

57 locations incl. Dothan

Sponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA

Sex: All·Age: 40 - 80

Code: NCT07016412·Phase 2·Recruiting

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A Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia Areata

for Severe Alopecia Areata

Drug: Ritlecitinib

29 locations incl. Encinitas

Sponsor: Pfizer

Sex: All·Age: 6 - 11

Code: NCT07029711·Phase 3·Recruiting

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Exploring the Effect of Calaspargase Pegol on the Coagulation System in Pediatric Acute Lymphoblastic Leukemia (ALL) Patients: Pilot Study

for Childhood Acute Lymphoblastic Leukemia

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 2 - 22

Code: NCT07071051·Recruiting

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A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)

for Multiple Myeloma

13 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07073547·Phase 1·Recruiting

Apply to this trial