Paid Clinical Trials in Minnesota

Minnesota has 2,364 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,364 clinical trials

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A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

for Non-obstructive Hypertrophic Cardiomyopathy

22 locations incl. La Jolla

Sponsor: Imbria Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07023614·Phase 2·Recruiting

Apply to this trial

Closed Loop and Education for Hypoglycemia Awareness Restoration

for Diabetes Mellitus, Type 1

5 locations incl. La Jolla

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06325202·Recruiting

Apply to this trial

The Effect of Glycemic Control and of GLP-1 Receptor Agonism on Islet GLP-1 in People With Type 1 and Type 2 Diabetes

for Type 1 Diabetes

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 25 - 70

Code: NCT06976619·Phase 2·Recruiting

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The Lilac Device Trial - IMPACT: A Clinical Investigation on IMproving Peripheral Neuropathy Induced by Chemotherapy With Advanced Compression Technology - A Safety and Efficacy Study

for Chemotherapy Induced Peripheral Neuropathy (CIPN)

17 locations incl. Poway

Sponsor: Luminate Medical, Inc.

Sex: All·Age: 18+

Code: NCT07142304·Recruiting

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Investigating EEG as a Biomarker for Tinnitus Improvement After Bimodal Stimulation

for Tinnitus

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07158034·Recruiting

Apply to this trial

A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

for Crohn Disease

58 locations incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07196722·Phase 2, Phase 3·Recruiting

Apply to this trial

Clinical Study of Neflamapimod in Patients With Primary Progressive Aphasia

for Nonfluent Variant Primary Progressive Aphasia (nfvPPA)

5 locations incl. Chicago

Sponsor: EIP Pharma Inc

Sex: All·Age: 40 - 85

Code: NCT07033481·Phase 2·Recruiting

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CMVIG Prophylaxis in Belatacept Conversion Kidney Transplant Recipients

for Kidney Transplant

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 70

Code: NCT07096453·Phase 1, Phase 2·Recruiting

Apply to this trial

CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

for Transthyretin Amyloid Cardiomyopathy (ATTR CM)

Drug: Coramitug

61 locations incl. Phoenix

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07207811·Phase 3·Recruiting

Apply to this trial

Personalized Approach to Healthy Use and Recovery (PATH) Trial

for Substance Use Disorder

1 location in Minneapolis

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06580457·Recruiting

Apply to this trial

Molecular and ctDNA Characterization of High-Risk Endometrial Cancer

for Endometrial Carcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT07062016·Recruiting

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Clinical Course Of Disease In Participants With FA-CM

for Friedreich Ataxia

8 locations incl. La Jolla

Sponsor: Lexeo Therapeutics

Sex: All·Age: 6+

Code: NCT06865482·Recruiting

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Evaluation of a Non-Implanted Electrical Stimulation Device for Overactive Bladder (OAB)

for Overactive Bladder (OAB)

15 locations incl. Beverly Hills

Sponsor: FemPulse Corporation

Sex: Female·Age: 21+

Code: NCT07195656·Recruiting

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Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)

for Primary Membranous Nephropathy

22 locations incl. Montgomery

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 75

Code: NCT07204275·Phase 2, Phase 3·Recruiting

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A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (mCRC)

for Colon Cancer

14 locations incl. Denver

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 18+

Code: NCT07011576·Phase 2·Recruiting

Apply to this trial

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

for Non-small Cell Carcinoma

133 locations incl. Alabaster

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07144280·Phase 3·Recruiting

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A Study of AAVB-039 in Participants With Stargardt Disease (STGD1)

for Stargardt Disease

5 locations incl. Phoenix

Sponsor: AAVantgarde Bio Srl

Sex: All·Age: 8 - 55

Code: NCT07161544·Phase 1, Phase 2·Recruiting

Apply to this trial

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

for Acute Myeloid Leukemia (AML)

42 locations incl. Gilbert

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT07007312·Phase 3·Recruiting

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Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

for Urothelial Cancer

38 locations incl. Fullerton

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT07129993·Phase 2, Phase 3·Recruiting

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A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease

for Immunoglobulin G4 Related Disease

17 locations incl. Fontana

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07190196·Phase 3·Recruiting

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A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza

for Influenza

120 locations incl. Anniston

Sponsor: Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Sex: All·Age: 12+

Code: NCT07159763·Phase 3·Recruiting

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A Phase I/II Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

for B-cell Non-Hodgkin Lymphoma

8 locations incl. Irvine

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07123454·Phase 1, Phase 2·Recruiting

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A Pilot Study Testing the Safety and Feasibility of Restorative Microbiota Therapy (RMT) in Patients With Refractory Immune-checkpoint Inhibitor-related Colitis

for Immune-related Colitis

9 locations incl. Brainerd

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05726396·Phase 2·Recruiting

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A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

for Hypothalamic Obesity

8 locations incl. Birmingham

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 4+

Code: NCT06760546·Phase 3·Recruiting

Apply to this trial

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

for Breast Cancer

14 locations incl. Orlando

Sponsor: Terremoto Biosciences Inc.

Sex: All·Age: 18+

Code: NCT07109726·Phase 1, Phase 2·Recruiting

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Senyo Health With Substance Use Disorder (SUD) in Primary Care

for Substance Use Disorders

2 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06743282·Enrolling By Invitation

Baby ABS (Abdominal Binder Study)

for Premature

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 26 Weeks - 31 Weeks

Code: NCT07049900·Recruiting

Apply to this trial

Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

for Plaque Psoriasis

Drug: Deucravacitinib

122 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 40+

Code: NCT07116967·Phase 3·Recruiting

Apply to this trial

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

for High Risk Cardiovascular Disease

Drug: Zilebesiran

247 locations incl. Birmingham

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07181109·Phase 3·Recruiting

Apply to this trial

Mindfulness and Meditation Based Lactation Education on Maternal Breastmilk in the Neonatal ICU

for Lactation

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 20+·Accepts healthy volunteers

Code: NCT07351799·Recruiting

Apply to this trial

Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)

for Primary Membranous Nephropathy

5 locations incl. Loma Linda

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18 - 75

Code: NCT07157787·Phase 2·Recruiting

Apply to this trial

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

for Cystic Fibrosis (CF)

18 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 12+

Code: NCT06837181·Recruiting

Apply to this trial

LTFU for All Cell and Gene Therapy Studies

for Hepatocellular Carcinoma

18 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06194461·Not Yet Recruiting

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for Anatomic Stage I Breast Cancer AJCC v8

652 locations incl. Phoenix

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06876714·Phase 3·Recruiting

Apply to this trial

Deciphering Preserved Autonomic Function After Multiple Sclerosis

for Multiple Sclerosis

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07012135·Recruiting

Apply to this trial

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

for Chronic Obstructive Pulmonary Disease

Drug: Lunsekimig

63 locations incl. Chandler

Sponsor: Sanofi

Sex: All·Age: 40 - 80

Code: NCT07190209·Phase 3·Recruiting

Apply to this trial

RISE Versus Advocacy-based Enhanced Care as Usual for Patients Experiencing IPV

for Intimate Partner Violence (IPV)

3 locations incl. Boston

Sponsor: Boston University

Sex: All·Age: 18+

Code: NCT06906302·Recruiting

Apply to this trial

Azithromycin Versus Doxycycline in Hospitalized Adult Patients With Community Acquired Pneumonia Treated With Beta-lactams

for Community-acquired Pneumonia

5 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07164131·Phase 4·Recruiting

Apply to this trial

Intent of Surgery for IPMN

for Intraductal Papillary Mucinous Neoplasm

8 locations incl. Phoenix

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT07216521·Recruiting

Apply to this trial

A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases

for Interstitial Lung Diseases

Drug: Nerandomilast

33 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06806592·Phase 3·Recruiting

Apply to this trial