Clinical Trials at St. Jude Children's Research Hospital

As of June 2026, 126 paid clinical trials are recruiting at St. Jude Children's Research Hospital, located at 262 DANNY THOMAS PL, MEMPHIS, TN 38105-3678, phone (901) 595-2911 in Memphis, Tennessee. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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126 clinical trials at St. Jude Children's Research Hospital

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Long-term Follow-up After Adoptive Transfer of Genetically Modified Cell Products

for Relapsed Hematologic Malignancy

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT05713214·Recruiting

Apply to this trial

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

for Medulloblastoma

10 locations incl. Palo Alto

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 59 Months

Code: NCT05535166·Phase 2·Recruiting

Apply to this trial

Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

for Hematopoietic Cell Transplant

27 locations incl. Birmingham

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: Up to 18

Code: NCT05550298·Recruiting

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Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

for Hematologic Malignancy

29 locations incl. Los Angeles

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 - 21

Code: NCT05476770·Phase 1·Recruiting

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Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

for Refractory Solid Tumor

Drug: Atezolizumab

2 locations incl. Germantown

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 30

Code: NCT05468359·Phase 1, Phase 2·Recruiting

Apply to this trial

Response to Influenza Vaccination in Pediatric Oncology Patients

for Hematologic Malignancy

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 18

Code: NCT05384288·Recruiting

Apply to this trial

The Decision To Enroll In Therapeutic Clinical Trials In A Pediatric Cancer Clinical Network

for Knowledge, Attitudes, Practice

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT05454618·Recruiting

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Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

45 locations incl. Phoenix

Sponsor: PedAL BCU, LLC

Sex: All·Age: 29 Days - 21

Code: NCT05183035·Phase 3·Recruiting

Apply to this trial

Discarded Bone Marrow for Hematology Research

for Hemoglobinopathies

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT04671212·Recruiting

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B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

for Pediatric Solid Tumor

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04897321·Phase 1·Recruiting

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A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors

for ALK Fusion-positive Solid or CNS Tumors

7 locations incl. Palo Alto

Sponsor: Hoffmann-La Roche

Sex: All·Age: Up to 17

Code: NCT04774718·Phase 1, Phase 2·Recruiting

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A Phase 2a Study of IV BCV in Subjects With Adenovirus Infection

for Adenovirus Infections

11 locations incl. Los Angeles

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT04706923·Phase 2·Recruiting

Apply to this trial

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

for Papillary Thyroid Cancer

8 locations incl. San Francisco

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0+

Code: NCT05024929·Recruiting

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SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

for Low-Grade Glioma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 2 - 24

Code: NCT04923126·Phase 1, Phase 2·Recruiting

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Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

for Recurrent Solid Tumor

7 locations incl. Palo Alto

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 12 Months - 30

Code: NCT04901702·Phase 1, Phase 2·Recruiting

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Study Of Cold Cap Therapy For Prevention of Hairloss in Pediatric Patients Receiving Chemotherapy For Non-Malignant Indications and Solid Tumors

for Alopecia

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 7+

Code: NCT04764357·Recruiting

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Childhood Cancer Predisposition Study (CCPS)

for Pediatric Cancer

6 locations incl. Atlanta

Sponsor: Emory University

Sex: All·Age: All ages

Code: NCT04511806·Recruiting

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Haploidentical HCT for Severe Aplastic Anemia

for Aplastic Anemia

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04558736·Phase 2·Recruiting

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A Long-term Follow-up Study in Participants Who Received CTX001

for Beta-Thalassemia

9 locations incl. Palo Alto

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 2+

Code: NCT04208529·Phase 3·Enrolling By Invitation

Sickle Cell Disease and the Genomic and Gene Therapy Needs of Stakeholders

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 13+·Accepts healthy volunteers

Code: NCT04416178·Recruiting

Apply to this trial

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

71 locations incl. Phoenix

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting

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Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase

for Acute Pancreatitis

3 locations incl. Charlotte

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04195347·Phase 1, Phase 2·Recruiting

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CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)

for AML/MDS

2 locations incl. Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04318678·Phase 1·Recruiting

Apply to this trial

Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body

for Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion

51 locations incl. Mesa

Sponsor: Bayer

Sex: All·Age: All ages

Code: NCT04142437·Recruiting

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A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

for Locally Advanced Solid Tumors

Drug: Repotrectinib

20 locations incl. Los Angeles

Sponsor: Turning Point Therapeutics, Inc.

Sex: All·Age: Up to 25

Code: NCT04094610·Phase 1, Phase 2·Recruiting

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Indocyanine Green (ICG) Guided Tumor Resection

for Neoplastic Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT04084067·Phase 1·Recruiting

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Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

for Glioma

2 locations incl. Rochester

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 6 - 21

Code: NCT04065776·Recruiting

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Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

for Pulmonary Invasive Fungal Infections

32 locations incl. Little Rock

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: 120 Days - 21

Code: NCT03827694·Recruiting

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Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease

for Sickle Cell Disease

2 locations incl. Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 6 - 25

Code: NCT03353584·Recruiting

Apply to this trial

Familial Investigations of Childhood Cancer Predisposition

for Acute Leukemia

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT03050268·Recruiting

Apply to this trial

Retinoblastoma Patient Clinical Database and Tissue Repository

for Retinoblastoma

8 locations incl. Phoenix

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 0 - 18

Code: NCT04959097·Recruiting

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Investigation of the Genetics of Hematologic Diseases

for Bone Marrow Failure Syndromes

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT02720679·Recruiting

Apply to this trial

Molecular Analysis of Childhood and Adolescent Melanocytic Lesions

for Melanoma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 18

Code: NCT02775643·Recruiting

Apply to this trial

Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology Patients

for Solid, Liquid, Central Nervous System Tumors

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT02530658·Recruiting

Apply to this trial

Sickle Cell Clinical Research and Intervention Program

for Sickle Cell Disease

6 locations incl. Peoria

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT02098863·Recruiting

Apply to this trial

Neuroblastoma Biology Study

for Neuroblastoma

16 locations incl. Los Angeles

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 31 Days - 99

Code: NCT01587300·Recruiting

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Natural History Study of SCID Disorders

for Severe Combined Immunodeficiency (SCID)

39 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: All ages

Code: NCT01186913·Enrolling By Invitation

Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

for Charcot-Marie-Tooth Disease, Type Ia (Disorder)

17 locations incl. Los Angeles

Sponsor: University of Iowa

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01193088·Recruiting

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Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

for Charcot Marie Tooth Disease

18 locations incl. Los Angeles

Sponsor: Michael Shy

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01193075·Recruiting

Apply to this trial

Molecular Analysis Of Solid Tumors

for Pediatric Solid Tumors

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 25

Code: NCT01050296·Recruiting

Apply to this trial