Retinoblastoma Patient Clinical Database and Tissue Repository

Part of paid clinical trials in Phoenix, Arizona.

Sponsor
Children's Hospital Los Angeles
Study ID
NCT04959097
Status
Recruiting
Apply to this trial

Conditions

  • Retinoblastoma
  • Retinoblastoma Bilateral
  • Retinoblastoma Unilateral

Eligibility Criteria

Sex
ALL
Age
0 Years - 18 Years
Healthy Volunteers
Not accepted

Study Details

Retinoblastoma (RB) is a primary eye cancer that forms in the back of the eye of infants and toddlers. Traditionally, RB is diagnosed without a biopsy; tumor can only be studied once an eye has been surgically removed. Given this limitation, we use aqueous humor (AH), the clear fluid in the front of the eye to detect specific markers, or information, that comes from the tumor itself.

Key Dates

Start date
Jan 1, 2017
Status verified
Apr 2026
Primary completion
Dec 31, 2028
Completion
Dec 31, 2030

Study Design

Enrollment
800 participants (estimated)

Primary Outcome Measure

Correlation of Ocular Salvage (eye saved) with biomarkers [ Time Frame: through study completion, a minimum of 12 months after diagnosis and average of 24 months ]

Central Contacts

Locations (8)

FacilityCityStateZIPSite coordinators
Phoenix Children's HospitalPhoenixArizona85016
Jennifer Nguyen
[email protected]
Merrylees Dersch, MD (PRINCIPAL_INVESTIGATOR)
Children's Hospital Los AngelesLos AngelesCalifornia90027
Jesse Berry, MD
[email protected]
323-361-4510
Emory University Children's Healthcare of ATLAtlantaGeorgia30322
Sarinee Juntipwong
[email protected]
404-778-4611
Hans Grossniklaus, MD (PRINCIPAL_INVESTIGATOR)
Ann & Robert H. Lurie Children's Hospital of ChicagoChicagoIllinois60611
Hanta Ralay-Ranaivo
[email protected]
Janice Lasky-Zeid, MD (PRINCIPAL_INVESTIGATOR)
Oregon Health & Science University: Casey Eye InstitutePortlandOregon97239
Ann Lundquist
[email protected]
Alison Skalet, M.D., Ph.D (PRINCIPAL_INVESTIGATOR)
Wills Eye InstitutePhiladelphiaPennsylvania19107
Lisa Cotelesa
Carol Shields, MD (PRINCIPAL_INVESTIGATOR)
St. Jude Children's Research HospitalMemphisTennessee38105
Dana Hawkins
[email protected]
Matthew Wilson, MD (PRINCIPAL_INVESTIGATOR)
Seattle Children's Hospital; University of WashingtonSeattleWashington98101
Jeff Stevens
[email protected]
Andrew Stacey, M.D., M.S (PRINCIPAL_INVESTIGATOR)

Find similar trials in Phoenix, AZ

By research site
Phoenix Children's Hospital· Phoenix, AZChildren's Hospital Los Angeles· Los Angeles, CAEmory University Children's Healthcare of ATL· Atlanta, GAAnn & Robert H. Lurie Children's Hospital of Chicago· Chicago, ILOregon Health & Science University: Casey Eye Institute· Portland, ORWills Eye Institute· Philadelphia, PA

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