Paid Clinical Trials in Maryland

Maryland has 2,900 paid clinical trials enrolling now across cities including Baltimore, Bethesda and Rockville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Maryland include Johns Hopkins Medicine and NIH Clinical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 18, 2026.

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2,900 clinical trials

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Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome

for Myelodysplastic Syndromes

7 locations incl. Jacksonville

Sponsor: Syntrix Biosystems, Inc.

Sex: All·Age: 18+

Code: NCT04245397·Phase 1·Recruiting

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Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)

for Neurofibromatosis Type 2

6 locations incl. Los Angeles

Sponsor: Scott R. Plotkin, MD, PhD

Sex: All·Age: 12+

Code: NCT04374305·Phase 2·Recruiting

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Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

for Pancreatic Neoplasm

408 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 50 - 75

Code: NCT04239573·Recruiting

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

1149 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting

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Data Collection of Standard Care and Evaluation of NHLBI Patients and Donors

for Wide Spectrum of Diseases

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 2 - 120·Accepts healthy volunteers

Code: NCT04450927·Enrolling By Invitation

HEALEY ALS Platform Trial - Master Protocol

for Amyotrophic Lateral Sclerosis

81 locations incl. Phoenix

Sponsor: Merit E. Cudkowicz, MD

Sex: All·Age: 18+

Code: NCT04297683·Phase 2, Phase 3·Recruiting

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International CIPN Assessment and Validation Study

for Chemotherapy-induced Peripheral Neuropathy

8 locations incl. Birmingham

Sponsor: University of Milano Bicocca

Sex: All·Age: 18+

Code: NCT04633655·Recruiting

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Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)

for Gastric Cancer

10 locations incl. Santa Monica

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT04379596·Phase 2·Recruiting

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COVID-19 Pandemic Impact on Alcohol (PIA) - A Natural History Study

for Alcohol Drinking

1 location in Bethesda

Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT04391816·Recruiting

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Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors

for VHL Pancreatic Neuroendocrine Tumors

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT04074135·Phase 2·Recruiting

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Osimertinib Alone or With Chemotherapy for EGFR-Mutant Lung Cancers

for Metastatic Non-small Cell Lung Cancer

Drug: Osimertinib

18 locations incl. Sacramento

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT04410796·Phase 2·Recruiting

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Study of CTDNA Response Adaptive Immuno-Chemotherapy in Lung Cancer

for Lung Cancer

2 locations incl. Chicago

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT04093167·Phase 2, Phase 3·Recruiting

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Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology Studies

for Cervical Intraepithelial Neoplasia

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT04266093·Enrolling By Invitation

Early Initiation of Oral Therapy With Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA)

for Severe Aplastic Anemia

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 3 - 99

Code: NCT04304820·Phase 2·Recruiting

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DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma

for Fibrolamellar Hepatocellular Carcinoma (FLC)

Drug: Ipilimumab

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 12+

Code: NCT04248569·Phase 1·Recruiting

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Developing a Test of Uterine Lavage for the Detection of Ovarian Cancer

for Ovarian Neoplasms

6 locations incl. Little Rock

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 30+

Code: NCT04794322·Recruiting

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The Impact of COVID-19 on Maternal and Neonatal Outcomes

for COVID-19

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Female·Age: 14 - 55·Accepts healthy volunteers

Code: NCT05197621·Recruiting

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Proton Radiation Therapy Registry

for Cancer, Therapy-Related

4 locations incl. Washington D.C.

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18 - 100

Code: NCT04376229·Recruiting

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Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body

for Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion

51 locations incl. Mesa

Sponsor: Bayer

Sex: All·Age: All ages

Code: NCT04142437·Recruiting

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Cohort/Ethics Study of Patients With Severe Alcoholic Hepatitis Undergoing Early Liver Transplantation

for Liver Diseases, Alcoholic

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT04234139·Enrolling By Invitation

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

for Malignancy

626 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: All ages

Code: NCT04242095·Recruiting

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Belimumab With Rituximab for Primary Membranous Nephropathy

for Membranous Nephropathy

Drug: Rituximab

20 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 75

Code: NCT03949855·Phase 2·Recruiting

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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

for Coronavirus Infection (COVID-19)

49 locations incl. Phoenix

Sponsor: Duke University

Sex: All·Age: 0 - 20·Accepts healthy volunteers

Code: NCT04278404·Recruiting

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CHIP/CCUS Natural History Protocol

for Clonal Hematopoiesis of Indeterminate Potential

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 99

Code: NCT04102423·Recruiting

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Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss

for Peripheral Artery Disease

7 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT04228978·Recruiting

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ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

for Frontotemporal Lobar Degeneration (FTLD)

25 locations incl. Birmingham

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04363684·Recruiting

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Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical Patient

for Iron Deficiency Anemia

1 location in Baltimore

Sponsor: Auerbach Hematology Oncology Associates P C

Sex: All·Age: 18+

Code: NCT04268849·Phase 3·Recruiting

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AMI Construction in Lower Extremity Residual Limbs

for Amputation

3 locations incl. Bethesda

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT04063592·Recruiting

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Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow

for Neuropathy Ulnar

10 locations incl. Atlanta

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT04254185·Recruiting

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The Youth Opioid Recovery Support (YORS) Intervention

for Opioid-use Disorder

1 location in Baltimore

Sponsor: Potomac Health Foundations

Sex: All·Age: 18 - 28

Code: NCT04173416·Recruiting

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Regenerative Medicine to Restore Hematopoiesis and Immune Function in Immunodeficiencies and Inherited Bone Marrow Failures

for Primary Immune Deficiency Disorder

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 4 Months - 50

Code: NCT04232085·Phase 2·Recruiting

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A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for Low Grade Astrocytoma

Drug: Selumetinib

124 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 - 21

Code: NCT04166409·Phase 3·Recruiting

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Reverse Phenotyping Core

for Harboring of Unexpected Genetic Variant

1 location in Bethesda

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 4 - 120

Code: NCT03632239·Enrolling By Invitation

Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression

for Depression

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 18 - 70

Code: NCT03973268·Phase 1·Recruiting

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Safety of Belimumab in People With Idiopathic CD4 Lymphopenia and Autoantibodies (Phoebe)

for Idiopathic CD4 Lymphopenia

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT04097561·Phase 1·Recruiting

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Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL

for Leukemia, Myeloid, Chronic

8 locations incl. Birmingham

Sponsor: Ascentage Pharma Group Inc.

Sex: All·Age: 18+

Code: NCT04260022·Phase 1·Recruiting

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LITT Followed by Hypofractionated RT for Recurrent Gliomas

for Glioblastoma

4 locations incl. Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 22+

Code: NCT04181684·Recruiting

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Regional or Extend LymphAdenectomy During Resection of Intrahepatic Cholangiocarcinoma

for Intrahepatic Cholangiocarcinoma

1 location in Baltimore

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Sex: All·Age: 18 - 80

Code: NCT04078230·Recruiting

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IDENTIFY Study: Natural History of Maternal Neoplasia

for Maternal Neoplasia

1 location in Bethesda

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: Female·Age: 18 - 100

Code: NCT04049604·Recruiting

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Paradoxical Tuberculosis Reactions in Patients Without HIV Infection

for Tuberculosis

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 99

Code: NCT04052022·Recruiting

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