The Youth Opioid Recovery Support (YORS) Intervention

Part of paid clinical trials in Baltimore, Maryland.

Sponsor
Potomac Health Foundations
Study ID
NCT04173416
Status
Recruiting
Apply to this trial

Conditions

  • Medication Adherence
  • Opioid-use Disorder

Eligibility Criteria

Sex
ALL
Age
18 Years - 28 Years
Healthy Volunteers
Not accepted

Interventions

  • Youth Opioid Recovery Support (YORS) — BEHAVIORAL
    The Youth Opioid Recovery Support (YORS) model is an innovative wrap-around approach that attempts to address barriers to treatment engagement in this vulnerable young adult population, especially difficulties with medication adherence. Its components include: (1) Home delivery of extended release naltrexone (XR-NTX) for OUD; (2) Engagement of families in collaborative treatment planning and monitoring focusing on medication adherence; (3) Assertive outreach from the treatment team including actively tracking and communicating with youth and families by text messaging and social media to promote engagement and adherence; and (4) Contingency management to provide incentives for medication adherence.

Study Details

Youth are disproportionately affected by the current opioid crisis with catastrophic consequences, and young adults with opioid use disorder (OUD) often struggle with adherence to relapse prevention medications. The Youth Opioid Recovery Support (YORS) model is a promising, innovative, wrap-around approach that addresses barriers to medication adherence and treatment engagement in an effort to improve public health outcomes in this vulnerable young adult population. This study seeks to refine the YORS intervention through stakeholder input and pilot iterative testing followed by an efficacy randomized controlled trial. This project will significantly contribute to our knowledge base of practical strategies to address the opioid crisis.

Key Dates

Start date
Feb 17, 2020
Status verified
Sep 2025
Primary completion
Aug 31, 2026
Completion
Aug 31, 2026

Study Design

Enrollment
150 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Youth Opioid Recovery Support (YORS)
    The Youth Opioid Recovery Support (YORS) model is an innovative wrap-around approach that attempts to address barriers to treatment engagement in this vulnerable young adult population, especially difficulties with medication adherence. Its components include: (1) Home delivery of extended release naltrexone (XR-NTX) for OUD; (2) Engagement of families in collaborative treatment planning and monitoring focusing on medication adherence; (3) Assertive outreach from the treatment team including actively tracking and communicating with youth and families by text messaging and social media to promote engagement and adherence; and (4) Contingency management to provide incentives for medication adherence. The specific components of YORS will be refined and adapted based on feedback from interviews and focus groups with various stakeholders. However, the basic framework outlined above is expected to persists.
  • No Intervention: Treatment As Usual
    TAU will contain patients who will be receiving treatment for opioid use disorder through their usual venues without the family engagement, assertive outreach, contingency management, and home delivery of medication. This often includes a referral and warm hand off to intensive outpatient SUD services and/or mental health care.

Primary Outcome Measure

Number of MOUD injections received (XR-NTX or XR-BUP) [ Time Frame: Treatment week 0 to 26 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mountain Manor Treatment CenterBaltimoreMaryland21229
Kevin Wenzel, PhD
[email protected]
4102331400
Marc Fishman, MD
[email protected]
4102331400

Find similar trials in Baltimore, MD

By research site
Mountain Manor Treatment Center· Baltimore, MD

Related Studies