Paid Clinical Trials in Maryland

Maryland has 2,891 paid clinical trials enrolling now across cities including Baltimore, Bethesda and Rockville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Maryland include Johns Hopkins Medicine and NIH Clinical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,888 clinical trials

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Preoperative Fasting vs. Not Fasting in Critically Ill Patients

for Critical Illness

19 locations incl. Palo Alto

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06751043·Recruiting

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Evaluating the Dose, Safety, Tolerability, and Immunogenicity of Mosaic Hexavalent Influenza Vaccine VRCFLUMOS0116-00-VP (FluMos-v2) With and Without ALFQ Adjuvant in Healthy Adults

for Influenza Prevention

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06863142·Phase 1·Recruiting

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External Post-Operative Skull Prosthesis to Prevent Sunken Flap Syndrome in Craniectomy Patients

for Craniectomy

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06899711·Recruiting

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First-in-Human Single and Multiple Dose of HL-400

for Parkinson Disease

1 location in Baltimore

Sponsor: Highlightll Pharmaceutical (USA) LLC

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06997484·Phase 1·Recruiting

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A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

for Carcinoma, Non-Small-Cell Lung

Drug: Adagrasib

54 locations incl. Birmingham

Sponsor: Mirati Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06875310·Phase 3·Recruiting

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Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

for Metastatic Hepatocellular Carcinoma

9 locations incl. Los Angeles

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06915753·Phase 1·Recruiting

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A Study Evaluating Neoadjuvant Chemoimmunotherapy With Immunosensitizing Radiation for Borderline Resectable Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

4 locations incl. Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+

Code: NCT06800339·Phase 1·Recruiting

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An Interventional Study of Infigratinib in Children With Hypochondroplasia

for Hypochondroplasia

7 locations incl. Oakland

Sponsor: QED Therapeutics, a BridgeBio company

Sex: All·Age: 3 - 18

Code: NCT06873035·Phase 2, Phase 3·Enrolling By Invitation

Proton SBRT for Spinal Metastasis

for Spinal Metastasis

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT06895564·Recruiting

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Placebo Impacts Sleep and Pain Modulation in Chronic Pain

for Chronic Pain

1 location in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 88

Code: NCT06225817·Recruiting

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Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

for Peripheral Arterial Diseases

9 locations incl. Phoenix

Sponsor: Angiodynamics, Inc.

Sex: All·Age: All ages

Code: NCT06777901·Phase 4·Recruiting

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A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

for Lupus Erythematosus, Systemic

15 locations incl. San Francisco

Sponsor: AstraZeneca

Sex: All·Age: 18 - 70

Code: NCT06897930·Phase 1, Phase 2·Recruiting

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Pediatric Neuroimaging

for Neurogimaging

1 location in Baltimore

Sponsor: National Institute on Aging (NIA)

Sex: All·Age: 9 - 14·Accepts healthy volunteers

Code: NCT06912724·Recruiting

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Pivotal Study of Voro Urologic Scaffold

for Radical Prostatectomy

19 locations incl. Phoenix

Sponsor: Levee Medical, Inc.

Sex: Male·Age: 45+

Code: NCT06873581·Phase 3·Recruiting

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Fertilo In Vitro Research Study and Trial

for In Vitro Maturation of Oocytes

13 locations incl. Clovis

Sponsor: Gameto, Inc.

Sex: Female·Age: 18 - 35·Accepts healthy volunteers

Code: NCT06858111·Phase 3·Recruiting

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Clinical Trial Evaluating the Efficacy of AGB101 for Reducing Hippocampal Overactivity in Older Adults

for Hippocampal Overactivity

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT06919926·Phase 2·Recruiting

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An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

for Progressive Pulmonary Fibrosis

23 locations incl. Birmingham

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06951217·Phase 2·Recruiting

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A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism

for Tumor Hyperinsulinism (Tumor HI)

8 locations incl. Chicago

Sponsor: Rezolute

Sex: All·Age: 18+

Code: NCT06881992·Phase 3·Recruiting

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Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

for Major Depressive Disorder

Drug: NBI-1065845

40 locations incl. Huntsville

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18+

Code: NCT06966401·Phase 3·Recruiting

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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for Stage I Mixed Cell Type Kidney Wilms Tumor

146 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT06401330·Phase 3·Recruiting

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Scents of Progress: Leveraging a Novel Device for Olfactory Training in Older Adults

for Olfactory Dysfunction

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 60+

Code: NCT06733636·Recruiting

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Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies

for Cancer

8 locations incl. Fort Smith

Sponsor: Elephas

Sex: All·Age: 18+

Code: NCT07327489·Recruiting

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Exercise and Monitoring With Post-Hospitalization Muscle Atrophy to Sustain Intrinsic Capacity and Strength

for Chronic Kidney Disease (CKD)

2 locations incl. Aurora

Sponsor: VA Office of Research and Development

Sex: All·Age: 55+

Code: NCT06607913·Recruiting

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Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis

for Psoriatic Arthritis

16 locations incl. Huntington Beach

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06865105·Phase 2·Recruiting

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Assessment of 11C-JMJ-129 for Imaging PDE4D in Brain and Whole Body of Healthy Volunteers

for Healthy

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 18 - 101·Accepts healthy volunteers

Code: NCT06874205·Phase 1·Recruiting

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A Study Comparing Standard Treatments in People With Non-Muscle Invasive Bladder Cancer (NMIBC)

for Non-Muscle Invasive Bladder Cancer

9 locations incl. Baltimore

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 21+

Code: NCT06929286·Phase 3·Recruiting

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320-detector Computed Tomography to Assess Myocardial Extracellular Volume Fraction in Patients With Atrial Fibrillation Before AF Ablation.

for Atrial Fibrillation

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+

Code: NCT06308094·Recruiting

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A Study of BGB-16673 Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors

for CLL

21 locations incl. Jonesboro

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06846671·Phase 3·Recruiting

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer

for Carcinoma, Non-Small Cell Lung

Drug: Rilvegostomig

37 locations incl. La Mesa

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06868277·Phase 3·Recruiting

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Functional Neuroimaging to Detect the Neural Signatures of the Unpleasantness of Pain and Effort

for Fatigue Syndrome, Chronic

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 18 - 50

Code: NCT06472622·EARLY_Phase 1·Recruiting

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Tissue Reinforcement for Breast Reconstruction (TRBR) Pivotal Clinical Study (REDEFINE)

for Breast Reconstruction Surgery

20 locations incl. Scottsdale

Sponsor: W.L.Gore & Associates

Sex: Female·Age: 22+

Code: NCT06556654·Recruiting

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Effects of Psilocybin in Patients With Amyotrophic Lateral Sclerosis

for Amyotrophic Lateral Sclerosis

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06656702·EARLY_Phase 1·Recruiting

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A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for Breast Cancer

51 locations incl. Phoenix

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06790693·Phase 3·Recruiting

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Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia

for Hypertriglyceridemia

Drug: Plozasiran

76 locations incl. Bakersfield

Sponsor: Arrowhead Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06822790·Phase 3·Recruiting

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Suramin for the Treatment of Autism Trial: KZ101 in a Male Pediatric Population With Autism Spectrum Disorder (ASD)

for Autism Spectrum Disorder (ASD)

3 locations incl. Phoenix

Sponsor: Children's Hospital of Orange County

Sex: Male·Age: 5 - 14

Code: NCT06866275·Phase 2·Recruiting

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Metagenomics Next-generation Sequencing Approach to Detect Microbial DNA/RNA Overtime in Individuals Undergoing Hematopoietic Stem Cell Transplant

for Hematopoietic Stem Cell Transplantation

1 location in Bethesda

Sponsor: National Institutes of Health Clinical Center (CC)

Sex: All·Age: 3 - 100

Code: NCT06904053·Recruiting

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A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH

for Metabolic Dysfunction-Associated Steatohepatitis

35 locations incl. Chandler

Sponsor: Boston Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06920043·Phase 2·Recruiting

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Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

for Extensive Stage Lung Small Cell Carcinoma

Drug: Atezolizumab

43 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06287775·Phase 1, Phase 2·Recruiting

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A Trial to Evaluate CSF ctDNA and Safety of Plixorafenib Alone or With Retifanlimab in Patients With BRAF-altered Glioma

for BRAF V600E Mutation

Drug: Retifanlimab

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT06610682·EARLY_Phase 1·Recruiting

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CardiolRx in Recurrent Pericarditis (MAVERIC Phase-3)

for Recurrent Pericarditis

21 locations incl. Phoenix

Sponsor: Cardiol Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06708299·Phase 3·Recruiting

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