RecruitingEarly Phase 1Drug trialEffects of Psilocybin in Patients With Amyotrophic Lateral SclerosisThis study aims to study the feasibility of psilocybin therapy for patients with Amyotropic Lateral Sclerosis (ALS) with depressed mood. The secondary objective is to assess its impact on depression, quality of life, hopelessness, and functional status in this patient population.