Paid Clinical Trials in Maryland

Maryland has 2,891 paid clinical trials enrolling now across cities including Baltimore, Bethesda and Rockville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Maryland include Johns Hopkins Medicine and NIH Clinical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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2,888 clinical trials

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Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis

for Osteonecrosis of the Femoral Head

10 locations incl. Los Angeles

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 90

Code: NCT06123481·Recruiting

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Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

for Lung Non-Small Cell Carcinoma

243 locations incl. Jonesboro

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06498635·Phase 3·Recruiting

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ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

for Corneal Transplant Failure

12 locations incl. Irvine

Sponsor: Massachusetts Eye and Ear Infirmary

Sex: All·Age: 18+

Code: NCT06753916·Phase 2·Recruiting

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The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

for Anesthesia

9 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06802224·Phase 4·Recruiting

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Telerehabilitation for Patients With Chronic Low Back Pain (TeleBACK Clinical Trial)

for Chronic Low Back Pain

3 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 64

Code: NCT06821607·Recruiting

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Safety and Effectiveness of ELLANSÉ®-S Dermal Filler in the Treatment of Nasolabial Folds

for Nasolabial Folds

7 locations incl. Scottsdale

Sponsor: AQTIS Medical B.V.

Sex: All·Age: 22+

Code: NCT06984835·Recruiting

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Signature Development and Validation Protocol for an Epigenetic Assay in Diagnosing Lung Cancer

for Lung Cancer

1 location in Glen Burnie

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07008664·Recruiting

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A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

for Non-small Cell Lung Cancer

5 locations incl. Lexington

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06731907·Phase 2·Recruiting

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Myofascial Dysfunction in Post Stroke Shoulder Pain

for Stroke

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06718413·Phase 2·Recruiting

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Cross-Sectional Evaluation of Persistence of SARS-CoV-2 Remnants After Recovery From Acute Infection

for PASC Post Acute Sequelae of COVID-19

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 18 - 110·Accepts healthy volunteers

Code: NCT06577467·Recruiting

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A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting

for Ulcerative Colitis

100 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18 - 80

Code: NCT06581328·Phase 4·Recruiting

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Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

for Metastatic Head and Neck Squamous Cell Carcinoma

177 locations incl. Little Rock

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06589804·Phase 3·Recruiting

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A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

for Gastrointestinal Stromal Tumor (GIST)

32 locations incl. Birmingham

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06655246·Phase 1·Recruiting

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First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours

for Hepatocellular Carcinoma

6 locations incl. La Jolla

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06795022·Phase 1, Phase 2·Recruiting

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Standard-of-Care Reduced-Intensity Conditioning (RIC) With 200 Versus 400 cGy of Total Body Irradiation (TBI) in Patients With Acute Leukemia Undergoing First Allogeneic Blood or Marrow Transplantation (BMT)

for Acute Leukemia

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: All ages

Code: NCT06803745·Recruiting

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Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY3537982

85 locations incl. Huntsville

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06890598·Phase 3·Recruiting

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DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

for Endometrial Cancer

Drug: Rilvegostomig

60 locations incl. Tucson

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT06989112·Phase 3·Recruiting

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Study Evaluating Xtressé Gummy Supplement in Women With Self-Perceived Thinning Hair

for Hair Thinning

4 locations incl. Maitland

Sponsor: Restore Biologics Holdings, Inc. dba Xtressé

Sex: Female·Age: 18 - 65

Code: NCT07224555·Enrolling By Invitation

Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

for Asthma

55 locations incl. Bakersfield

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT06932263·Phase 2·Recruiting

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Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

for Metastatic Sarcoma

2 locations incl. Washington D.C.

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: Up to 39

Code: NCT06796543·Recruiting

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A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

for Chronic Obstructive Pulmonary Disease (COPD)

68 locations incl. Cullman

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06878261·Phase 3·Recruiting

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Studying TAK-243 in Patients With Advanced Cancer

for Advanced Lymphoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06223542·Phase 1·Recruiting

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Durability of Suppl. Rod Constructs-SuppleMentAry Rod Technique for Long-segment Posterior Instrumented Spinal Fusions

for Spinal Fusion

9 locations incl. Redwood City

Sponsor: AO Foundation, AO Spine

Sex: All·Age: 45+

Code: NCT06368245·Recruiting

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A Comparison of NeuroSpan Bridge, NeuraGen Nerve Guide, and Nerve Autograft for Peripheral Nerve Repair

for Peripheral Nerve Injuries

6 locations incl. San Francisco

Sponsor: Auxilium Biotechnologies

Sex: All·Age: 18 - 80

Code: NCT06529835·Recruiting

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

76 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting

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Efficacy of Fusidic Acid 1% in the Treatment of Bacterial Conjunctivitis

for Bacterial Conjunctivitis

38 locations incl. Little Rock

Sponsor: Baxis Pharmaceuticals, Inc.

Sex: All·Age: All ages

Code: NCT06911424·Phase 3·Recruiting

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Vortioxetine for the Treatment of Mood and Cognitive Symptoms in Frontotemporal Dementia

for Fronto-temporal Dementia

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 45+·Accepts healthy volunteers

Code: NCT06604520·Phase 2·Recruiting

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Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01)

for Lung Neoplasm Malignant

8 locations incl. Daphne

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06788912·Phase 2·Recruiting

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PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder

for Alcohol Use Disorder

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 18 - 70

Code: NCT06795581·Phase 1·Recruiting

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A Study of Navenibart in Participants With Hereditary Angioedema

for Hereditary Angioedema (HAE)

Drug: navenibart

19 locations incl. Birmingham

Sponsor: Astria Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT06842823·Phase 3·Enrolling By Invitation

Effect of Cannabis on E-Cigarette Use Behavior

for Cannabis Use

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06609109·Phase 1·Recruiting

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Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

for Ovarian Cancer

Drug: Bevacizumab

28 locations incl. La Jolla

Sponsor: Daiichi Sankyo

Sex: Female·Age: 18+

Code: NCT06819007·Phase 3·Recruiting

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A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

for Psoriasis

Drug: Tirzepatide

40 locations incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06857942·Phase 4·Recruiting

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Peer Behavioral Activation Utilization to Improve Substance Use and HIV Outcomes in People Receiving Long Acting Injectable-PrEP/ART (PUSH)

for HIV Infections

2 locations incl. Washington D.C.

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 88·Accepts healthy volunteers

Code: NCT06501781·Recruiting

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A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

for Chronic Obstructive Pulmonary Disease (COPD)

67 locations incl. Foley

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06883305·Phase 3·Recruiting

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External Facilitation to Increase Prescribing of AUD Medications in the Psychiatric Setting

for Alcohol-Related Disorders

1 location in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 90

Code: NCT07053098·Recruiting

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Phase II Study of Pacritinib in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric Castleman Disease and KSHV-Associated Inflammatory Cytokine Syndrome (KICS)

for KSHV Inflammatory Cytokine Syndrome (KICS)

Drug: Pacritinib

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06052618·Phase 2·Recruiting

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A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

for Triple Negative Breast Neoplasms

38 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06841354·Phase 3·Recruiting

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Evaluating Gardasil HPV Vaccine Humoral and Cellular Immune Responses in People With and Without HIV

for Human Papilloma Virus

2 locations incl. Washington D.C.

Sponsor: University of Maryland, Baltimore

Sex: Male·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06624839·Phase 2·Recruiting

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Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

for Clear Cell Renal Cell Carcinoma

414 locations incl. Phoenix

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06661720·Phase 3·Recruiting

Apply to this trial