Oncology Clinical Trials in Madison, WI

As of June 2026, 160 paid clinical trials are recruiting for Oncology in Madison, Wisconsin. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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160 clinical trials for Oncology

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Study of ORIC-944 in Patients With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

20 locations incl. Colorado Springs

Sponsor: ORIC Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT05413421·Phase 1·Recruiting

Apply to this trial

Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer

for Breast Cancer

1 location in Madison

Sponsor: University of Wisconsin, Madison

Sex: Female·Age: 40+

Code: NCT03936478·Phase 2·Recruiting

Apply to this trial

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

164 locations incl. Birmingham

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting

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Hypofractionated vs Conventional Fractionated RT in Soft Tissue Sarcomas

for Soft Tissue Sarcoma

1 location in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+

Code: NCT05109494·Phase 2·Recruiting

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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

219 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting

Apply to this trial

A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for Cervical Cancer

134 locations incl. Goodyear

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT04831580·Recruiting

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Androgen Deprivation, With or Without pTVG-AR, and With or Without T-Cell Checkpoint Blockade, in Patients With Newly Diagnosed, High-Risk Prostate Cancer

for Prostate Cancer

1 location in Madison

Sponsor: University of Wisconsin, Madison

Sex: Male·Age: 18+

Code: NCT04989946·Phase 1, Phase 2·Recruiting

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First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for PIK3CA Mutation

24 locations incl. Tucson

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05216432·Phase 1·Recruiting

Apply to this trial

Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

843 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting

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High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

for Metastatic Prostate Cancer

17 locations incl. Aurora

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT05011383·Phase 2·Recruiting

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Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors

for Advanced Solid Tumor

10 locations incl. La Jolla

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT05007782·Phase 1·Recruiting

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Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

for Prostate Cancer

20 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT04787744·Phase 2, Phase 3·Recruiting

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Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

for Solid Tumor

Drug: Givastomig

11 locations incl. Orange

Sponsor: I-Mab Biopharma US Limited

Sex: All·Age: 18+

Code: NCT04900818·Phase 1·Recruiting

Apply to this trial

Evaluation of PSMA in HER2- AR+ Metastatic Breast Cancer

for Breast Cancer

1 location in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+

Code: NCT04573231·Phase 2·Recruiting

Apply to this trial

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

621 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting

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DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)

for Breast Cancer

19 locations incl. Tucson

Sponsor: Criterium, Inc.

Sex: All·Age: All ages

Code: NCT04567420·Phase 2·Recruiting

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A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

for Acral Lentiginous Melanoma

Drug: Ipilimumab

331 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04511013·Phase 2·Recruiting

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

for Advanced Solid Tumor

32 locations incl. Irvine

Sponsor: PMV Pharmaceuticals, Inc

Sex: All·Age: 12+

Code: NCT04585750·Phase 1, Phase 2·Recruiting

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Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for Biochemically Recurrent Prostate Carcinoma

Drug: Apalutamide

342 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male·Age: 18+

Code: NCT04423211·Phase 3·Recruiting

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A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

539 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

185 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting

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Oxaliplatin and Liposomal Irinotecan (Plus Trastuzumab for HER2-positive Disease) in Advanced Esophageal and Gastric Adenocarcinoma

for Esophageal Adenocarcinoma

Drug: Irinotecan

1 location in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+

Code: NCT04150640·Phase 2·Recruiting

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Comparing Dosing Intervals of Nivolumab or Pembrolizumab in Locally Advanced or Metastatic Cancers

for Metastatic Cancer

Drug: Nivolumab

2 locations incl. Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT04295863·Phase 1·Recruiting

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

1150 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

203 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting

Apply to this trial

Pan Tumor Rollover Study

for Cancer

59 locations incl. Huntsville

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT03899155·Phase 2·Recruiting

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Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

for Breast Cancer

451 locations incl. Fairbanks

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 35+

Code: NCT03488693·Phase 3·Recruiting

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Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma

for Hodgkin Lymphoma

Drug: Ruxolitinib

6 locations incl. Chicago

Sponsor: Veronika Bachanova

Sex: All·Age: 18+

Code: NCT03681561·Phase 1, Phase 2·Recruiting

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Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for Neoplasms

100 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: All ages

Code: NCT03435796·Phase 2, Phase 3·Recruiting

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

152 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting

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APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

for Solid Tumors

6 locations incl. Los Angeles

Sponsor: Apollomics Inc.

Sex: All·Age: 18+

Code: NCT03175224·Phase 2·Recruiting

Apply to this trial

Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma

for Glioblastoma Multiforme

12 locations incl. Los Angeles

Sponsor: Neonc Technologies, Inc.

Sex: All·Age: 18+

Code: NCT02704858·Phase 1, Phase 2·Recruiting

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International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

48 locations incl. Birmingham

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting

Apply to this trial

A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study

for Prostate Cancer

50 locations incl. Anchorage

Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male·Age: 18+

Code: NCT02960022·Phase 2·Recruiting

Apply to this trial

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

for Head and Neck Squamous Cell Carcinoma

676 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT02734537·Phase 2·Recruiting

Apply to this trial

Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

for Acute Myeloid Leukemia

1 location in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 7 Months - 21

Code: NCT02508038·Phase 1·Recruiting

Apply to this trial

Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

245 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting

Apply to this trial

A Long-term Extension Study of PCI-32765 (Ibrutinib)

for Chronic Lymphocytic Leukemia

Drug: Ibrutinib

32 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT01804686·Phase 3·Recruiting

Apply to this trial

Targeted Genomic Analysis of Blood and Tissue Samples From Patients With Cancer

for Malignant Neoplasm

11 locations incl. Brick

Sponsor: Rutgers, The State University of New Jersey

Sex: All·Age: 1+

Code: NCT02688517·Recruiting

Apply to this trial

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

142 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting

Apply to this trial

Conditions in Oncology (Madison, WI)

Solid tumor· 26 Breast cancer· 24 Prostate cancer· 17 Cancer (any)· 15 Non-small cell lung cancer (NSCLC)· 13 Acute myeloid leukemia (AML)· 12 Metastatic prostate cancer· 10 Melanoma· 10 Metastatic breast cancer· 9 Colorectal cancer· 9 Ovarian cancer· 6 Multiple myeloma· 6 Gastric cancer· 5 Gastroesophageal junction cancer· 5 Chronic lymphocytic leukemia (CLL)· 5 Myelodysplastic syndromes (MDS)· 5 Non-Hodgkin lymphoma· 5 HER2-negative breast cancer· 4 Pancreatic cancer· 4 Biliary tract cancer· 4 Endometrial cancer· 4 Hodgkin lymphoma· 4 Hematologic malignancy· 4 Head and neck cancer· 4 HER2-positive breast cancer· 3 Lung cancer· 3 Kidney cancer· 3 Glioblastoma· 3 Glioma· 3 Acute lymphoblastic leukemia· 3 Leukemia (other)· 3 Diffuse large B-cell lymphoma (DLBCL)· 3 Small lymphocytic lymphoma· 3 Osteosarcoma· 3 Neuroblastoma· 3 Triple-negative breast cancer· 2 Metastatic colorectal cancer· 2 Esophageal cancer· 2 Fallopian tube cancer· 2 Brain cancer· 2 Mantle cell lymphoma· 2 Thyroid cancer· 2 Sarcoma· 2 Small cell lung cancer· 1 Colon cancer· 1 Gastrointestinal cancer· 1 Bladder cancer· 1 Cervical cancer· 1 Myeloproliferative neoplasm· 1 Follicular lymphoma· 1 Soft tissue sarcoma· 1 Ewing sarcoma· 1 Rhabdomyosarcoma· 1 Neuroendocrine tumors· 1