A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
for Ovarian Neoplasms
20 locations incl. Newport Beach
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07213791·Phase 1·Recruiting
Breast cancer Clinical Trials in Madison, WI
As of June 2026, 24 paid clinical trials are recruiting for Breast cancer in Madison, Wisconsin. Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Madison
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24 clinical trials for Breast cancer
·Clear filters·↓ Download CSVA Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
for HER2-positive Breast Cancer
22 locations incl. Long Beach
Sponsor: Jazz Pharmaceuticals
Sex: All·Age: 18+
Code: NCT07102381·Phase 2·Recruiting
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
for PIK3CA Mutation
51 locations incl. Gilbert
Sponsor: Relay Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT06982521·Phase 3·Recruiting
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
for Breast Neoplasms
33 locations incl. Daphne
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT07060807·Phase 3·Recruiting
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
for Breast Neoplasms
53 locations incl. Gilbert
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT06966700·Phase 3·Recruiting
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
for Breast Carcinoma
464 locations incl. Fairbanks
Sponsor: Wake Forest University Health Sciences
Sex: All·Age: 18+
Code: NCT06418204·Recruiting
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
for Breast Cancer
165 locations incl. Daphne
Sponsor: Stemline Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT06492616·Phase 3·Recruiting
Study of 18F-FFNP Breast PET/MRI
for Breast Cancer
1 location in Madison
Sponsor: University of Wisconsin, Madison
Sex: Female·Age: 18+
Code: NCT06086704·Phase 2·Recruiting
A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.
for Breast Cancer
5 locations incl. Los Angeles
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 18 - 100
Code: NCT06247995·Phase 1, Phase 2·Recruiting
A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors
for Breast Neoplasms
82 locations incl. Tucson
Sponsor: Seagen, a wholly owned subsidiary of Pfizer
Sex: All·Age: 18+
Code: NCT06157892·Phase 2·Recruiting
Biomarkers to Detect Endocrine Therapy Resistance
for Metastatic Cancer
1 location in Madison
Sponsor: University of Wisconsin, Madison
Sex: All·Age: 18+
Code: NCT06067503·Phase 2·Recruiting
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
for Breast Neoplasms
46 locations incl. Chandler
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT06312176·Phase 3·Recruiting
Tucatinib+Trastuzumab+Eribulin in HER2+ MBC
for Breast Cancer
6 locations incl. Aurora
Sponsor: Criterium, Inc.
Sex: All·Age: 18+
Code: NCT05458674·Phase 2·Recruiting
A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer
for Breast Cancer
Drug: Durvalumab
64 locations incl. Daphne
Sponsor: AstraZeneca
Sex: All·Age: 18+
Code: NCT06103864·Phase 3·Recruiting
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
1208 locations incl. Birmingham
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting
Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer
for Breast Cancer
45 locations incl. Dothan
Sponsor: Stemline Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT05563220·Phase 1, Phase 2·Recruiting
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
for Acute Lymphoblastic Leukemia
746 locations incl. Anchorage
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 40 - 75·Accepts healthy volunteers
Code: NCT05334069·Recruiting
Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers
for Breast Cancer
4 locations incl. Chicago
Sponsor: Ruth O'Regan
Sex: All·Age: 18+
Code: NCT04886531·Phase 2·Recruiting
Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer
for Breast Cancer
1 location in Madison
Sponsor: University of Wisconsin, Madison
Sex: Female·Age: 40+
Code: NCT03936478·Phase 2·Recruiting
First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer
for PIK3CA Mutation
24 locations incl. Tucson
Sponsor: Relay Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT05216432·Phase 1·Recruiting
Evaluation of PSMA in HER2- AR+ Metastatic Breast Cancer
for Breast Cancer
1 location in Madison
Sponsor: University of Wisconsin, Madison
Sex: All·Age: 18+
Code: NCT04573231·Phase 2·Recruiting
DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)
for Breast Cancer
19 locations incl. Tucson
Sponsor: Criterium, Inc.
Sex: All·Age: All ages
Code: NCT04567420·Phase 2·Recruiting
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
for Advanced Solid Tumor
32 locations incl. Irvine
Sponsor: PMV Pharmaceuticals, Inc
Sex: All·Age: 12+
Code: NCT04585750·Phase 1, Phase 2·Recruiting
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer
for Breast Cancer
451 locations incl. Fairbanks
Sponsor: Canadian Cancer Trials Group
Sex: Female·Age: 35+
Code: NCT03488693·Phase 3·Recruiting
About research studies in Madison
Madison has approximately 604 recruiting research studies across a wide range of therapeutic areas. Wisconsin hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Madison
Researchers run research studies in Madison, WI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Wisconsin | Cystic Fibrosis, Alzheimer Disease, Healthy | 123 |
| University of Wisconsin Carbone Cancer Center - University Hospital | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Malignant Solid Neoplasm | 92 |
| University of Wisconsin Carbone Cancer Center - Eastpark Medical Center | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Metastatic Malignant Solid Neoplasm | 61 |
| University of Wisconsin - Madison | Gastroschisis, Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL) | 37 |
| University of Wisconsin Carbone Cancer Center | Prostate Cancer, Breast Cancer, Acute Myeloid Leukemia | 33 |
| University of Wisconsin-Madison | Achondroplasia, Acute Respiratory Failure, Acute Respiratory Infection | 21 |
| William S Middleton VA Medical Center | Acute Myeloid Leukemia, Myelodysplastic Syndrome, RISS Stage I Plasma Cell Myeloma | 12 |
| William S. Middleton Memorial Veterans Hospital, Madison, WI | Metastatic Prostate Cancer, Aging, Asymptomatic Bacteriuria | 12 |
| UW School of Medicine and Public Health | Diabetic Retinopathy, Aphasia, Diabetes Mellitus | 11 |
| University of Wisconsin Hospital and Clinics | Pulmonary Hypertension, AML With Mutated NPM1, Acute Myeloid Leukemia | 11 |
| University of Wisconsin Madison | Asthma, Alzheimer's Disease, Asthma Chronic | 8 |
| University of Wisconsin School of Medicine and Public Health | Abdominal Imaging, Breast Cancer, Development of Reporting System for Molecular Diagnosis | 8 |
| UW Carbone Cancer Center | Breast Cancer, Metastatic Cancer, Advanced Breast Cancer | 7 |
| UW Hospital and Clinics | Cytomegalovirus Infections, Diabetic Retinopathy, High-need, High-complexity | 7 |
| American Family Children's Hospital | Cardiac Arrest, Out-Of-Hospital, Hospitalized Child, Hypothermia, Induced | 6 |
| University of Wisconsin, Madison | Atrial Arrhythmia, Atrial Tachycardia, CLOVES Syndrome | 6 |
| University of Wisconsin Clinical Science Center | Breast Cancer, Cervical Cancer, Leukemia | 5 |
| Meriter Hospital | Delirium, Aging, Alzheimer Disease | 4 |
| SSM Health Dean Medical Group - South Madison Campus | Malignant Solid Neoplasm, RISS Stage I Plasma Cell Myeloma, RISS Stage II Plasma Cell Myeloma | 4 |
| UW Health University Hospital | Consciousness Disorders, Fracture Fixation, Idiopathic Pulmonary Fibrosis | 4 |
| University Hospital and UW Health Clinics | Interstitial Lung Disease, Progressive Pulmonary Fibrosis, Achondroplasia | 4 |
| University of Wisconsin Madison - Waisman Center Bone Dysplasia Clinic | Hypochondroplasia, Achondroplasia | 4 |
| Center for Healthy Minds | Asthma, Depression, Anxiety, Well-Being, Psychological | 3 |
| East Madison Hospital | Delirium, Falls-Risk, Opiate Use Disorder | 3 |
| Fortrea Clinical Research Unit Inc. | Healthy, Healthy Male Volunteers, Healthy Volunteers | 3 |
Active & Upcoming Studies in Madison (2026)
Recruiting trials in Madison grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (227 active studies)
- Maximizing Quality of Life After Cancer Through Rehabilitation · VA Office of Research and Development
- Study of Selinexor With Carfilzomib, Isatuximab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma · Phase 1, Phase 2 · Natalie Callander
Cardiovascular (28 active studies)
- Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children · University of Wisconsin, Madison
- Randomized Trial of SGLT2i in Heart Transplant Recipients · Phase 4 · VA Office of Research and Development
Neurology & pain (25 active studies)
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
- The Gut - PRO Study · Phase 2 · University of Wisconsin, Madison
Mental health & behavior (19 active studies)
- Music Interventions During Wide-Awake Hand Surgery · University of Wisconsin, Madison
- Varenicline for Smoking Reduction in Veterans Not Ready To Quit · Phase 4 · VA Office of Research and Development
Diabetes & metabolic (14 active studies)
- Leveraging Artificial Intelligence to Prevent Vision Loss From Diabetes · University of Wisconsin, Madison
- Human Cerebrovascular Blood Flow and Sex Differences in Metabolic Syndrome · EARLY_Phase 1 · University of Wisconsin, Madison
Pediatric (13 active studies)
- Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children · University of Wisconsin, Madison
- Testing and Evaluating an Interactive Media Use Journal for Adolescents · University of Wisconsin, Madison
Eye & vision (4 active studies)
- A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio · Phase 2 · Apellis Pharmaceuticals, Inc.
- Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID) · University of Wisconsin, Madison
Vaccines (2 active studies)
- ORCHARDS-AIR Study · University of Wisconsin, Madison
- Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) · Duke University
Common conditions studied in Madison
- Breast Cancer (17 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Prostate Cancer (14 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Acute Myeloid Leukemia (10 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Healthy (8 active studies). Healthy-volunteer studies examine how new drugs behave in the body, helping researchers understand safety and dosing before later-phase trials.
- Metastatic Breast Cancer (7 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Metastatic Cancer (7 active studies). Recruiting Metastatic Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Madison
- University of Wisconsin, Madison
- National Cancer Institute (NCI)
- Children's Oncology Group
- Merck Sharp & Dohme LLC
- VA Office of Research and Development
Local regulations and guidelines
Clinical trials in Wisconsin are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Wisconsin research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Madison. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Madison
Hipa.ai aggregates every recruiting study in Madison from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Madison?
There are approximately 604 recruiting clinical trials in Madison, Wisconsin listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Madison pay participants?
Most recruiting trials in Madison compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Madison?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Madison?
The most common conditions under active study in Madison include Breast Cancer (17), Prostate Cancer (14), Acute Myeloid Leukemia (10), Healthy (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Madison?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Madison on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Madison?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Madison?
Recruiting research sites in Madison include University of Wisconsin, University of Wisconsin Carbone Cancer Center - University Hospital, University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Madison right now?
The largest active categories in Madison are Cancer & tumors (227), Cardiovascular (28), Neurology & pain (25). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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