Oncology Clinical Trials in Madison, WI
As of June 2026, 160 paid clinical trials are recruiting for Oncology in Madison, Wisconsin. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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160 clinical trials for Oncology
·Clear filters·↓ Download CSVStudy of Selinexor With Carfilzomib, Isatuximab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma
Chemical-Shift-Encoded MRI for Active Bone Marrow Dosimetry in Radiopharmaceutical Therapy
A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
Y-NM600 in Patients Receiving Anti-PD-1 or Anti-PD-L1 for Metastatic Cancer
Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis
Cognitive Impact of Neoadjuvant Chemotherapy for Ovarian Cancer
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis
Evaluating the Communication Between Patients and Providers in Cancer Clinics
A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity
A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer
Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)
Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer
Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
A Study of Lorigerlimab in Participants With Advanced Solid Tumors
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)
Using Novel Imaging to More Safely Treat Neuroendocrine Tumors
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
In Vivo Liquid Biopsy of Melanoma (Cytophone)
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
A Long-Term Follow-Up Basket Study for Participants Treated With SynKIR Chimeric Antigen Receptor (CAR) T Cell Product
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors
About research studies in Madison
Madison has approximately 604 recruiting research studies across a wide range of therapeutic areas. Wisconsin hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Madison
Researchers run research studies in Madison, WI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Wisconsin | Cystic Fibrosis, Alzheimer Disease, Healthy | 123 |
| University of Wisconsin Carbone Cancer Center - University Hospital | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Malignant Solid Neoplasm | 92 |
| University of Wisconsin Carbone Cancer Center - Eastpark Medical Center | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Metastatic Malignant Solid Neoplasm | 61 |
| University of Wisconsin - Madison | Gastroschisis, Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL) | 37 |
| University of Wisconsin Carbone Cancer Center | Prostate Cancer, Breast Cancer, Acute Myeloid Leukemia | 33 |
| University of Wisconsin-Madison | Achondroplasia, Acute Respiratory Failure, Acute Respiratory Infection | 21 |
| William S Middleton VA Medical Center | Acute Myeloid Leukemia, Myelodysplastic Syndrome, RISS Stage I Plasma Cell Myeloma | 12 |
| William S. Middleton Memorial Veterans Hospital, Madison, WI | Metastatic Prostate Cancer, Aging, Asymptomatic Bacteriuria | 12 |
| UW School of Medicine and Public Health | Diabetic Retinopathy, Aphasia, Diabetes Mellitus | 11 |
| University of Wisconsin Hospital and Clinics | Pulmonary Hypertension, AML With Mutated NPM1, Acute Myeloid Leukemia | 11 |
| University of Wisconsin Madison | Asthma, Alzheimer's Disease, Asthma Chronic | 8 |
| University of Wisconsin School of Medicine and Public Health | Abdominal Imaging, Breast Cancer, Development of Reporting System for Molecular Diagnosis | 8 |
| UW Carbone Cancer Center | Breast Cancer, Metastatic Cancer, Advanced Breast Cancer | 7 |
| UW Hospital and Clinics | Cytomegalovirus Infections, Diabetic Retinopathy, High-need, High-complexity | 7 |
| American Family Children's Hospital | Cardiac Arrest, Out-Of-Hospital, Hospitalized Child, Hypothermia, Induced | 6 |
| University of Wisconsin, Madison | Atrial Arrhythmia, Atrial Tachycardia, CLOVES Syndrome | 6 |
| University of Wisconsin Clinical Science Center | Breast Cancer, Cervical Cancer, Leukemia | 5 |
| Meriter Hospital | Delirium, Aging, Alzheimer Disease | 4 |
| SSM Health Dean Medical Group - South Madison Campus | Malignant Solid Neoplasm, RISS Stage I Plasma Cell Myeloma, RISS Stage II Plasma Cell Myeloma | 4 |
| UW Health University Hospital | Consciousness Disorders, Fracture Fixation, Idiopathic Pulmonary Fibrosis | 4 |
| University Hospital and UW Health Clinics | Interstitial Lung Disease, Progressive Pulmonary Fibrosis, Achondroplasia | 4 |
| University of Wisconsin Madison - Waisman Center Bone Dysplasia Clinic | Hypochondroplasia, Achondroplasia | 4 |
| Center for Healthy Minds | Asthma, Depression, Anxiety, Well-Being, Psychological | 3 |
| East Madison Hospital | Delirium, Falls-Risk, Opiate Use Disorder | 3 |
| Fortrea Clinical Research Unit Inc. | Healthy, Healthy Male Volunteers, Healthy Volunteers | 3 |
Active & Upcoming Studies in Madison (2026)
Recruiting trials in Madison grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (227 active studies)
- Maximizing Quality of Life After Cancer Through Rehabilitation · VA Office of Research and Development
- Study of Selinexor With Carfilzomib, Isatuximab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma · Phase 1, Phase 2 · Natalie Callander
Cardiovascular (28 active studies)
- Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children · University of Wisconsin, Madison
- Randomized Trial of SGLT2i in Heart Transplant Recipients · Phase 4 · VA Office of Research and Development
Neurology & pain (25 active studies)
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
- The Gut - PRO Study · Phase 2 · University of Wisconsin, Madison
Mental health & behavior (19 active studies)
- Music Interventions During Wide-Awake Hand Surgery · University of Wisconsin, Madison
- Varenicline for Smoking Reduction in Veterans Not Ready To Quit · Phase 4 · VA Office of Research and Development
Diabetes & metabolic (14 active studies)
- Leveraging Artificial Intelligence to Prevent Vision Loss From Diabetes · University of Wisconsin, Madison
- Human Cerebrovascular Blood Flow and Sex Differences in Metabolic Syndrome · EARLY_Phase 1 · University of Wisconsin, Madison
Pediatric (13 active studies)
- Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children · University of Wisconsin, Madison
- Testing and Evaluating an Interactive Media Use Journal for Adolescents · University of Wisconsin, Madison
Eye & vision (4 active studies)
- A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio · Phase 2 · Apellis Pharmaceuticals, Inc.
- Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID) · University of Wisconsin, Madison
Vaccines (2 active studies)
- ORCHARDS-AIR Study · University of Wisconsin, Madison
- Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) · Duke University
Common conditions studied in Madison
- Breast Cancer (17 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Prostate Cancer (14 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Acute Myeloid Leukemia (10 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Healthy (8 active studies). Healthy-volunteer studies examine how new drugs behave in the body, helping researchers understand safety and dosing before later-phase trials.
- Metastatic Breast Cancer (7 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Metastatic Cancer (7 active studies). Recruiting Metastatic Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Madison
- University of Wisconsin, Madison
- National Cancer Institute (NCI)
- Children's Oncology Group
- Merck Sharp & Dohme LLC
- VA Office of Research and Development
Local regulations and guidelines
Clinical trials in Wisconsin are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Wisconsin research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Madison. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Madison
Hipa.ai aggregates every recruiting study in Madison from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Madison?
There are approximately 604 recruiting clinical trials in Madison, Wisconsin listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Madison pay participants?
Most recruiting trials in Madison compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Madison?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Madison?
The most common conditions under active study in Madison include Breast Cancer (17), Prostate Cancer (14), Acute Myeloid Leukemia (10), Healthy (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Madison?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Madison on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Madison?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Madison?
Recruiting research sites in Madison include University of Wisconsin, University of Wisconsin Carbone Cancer Center - University Hospital, University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Madison right now?
The largest active categories in Madison are Cancer & tumors (227), Cardiovascular (28), Neurology & pain (25). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.