Madison, WI Clinical Trials Report — April 2026

For Madison residents considering participation in clinical research, April 2026 presents a crucial window for those looking to join studies before enrollment closes. Across Madison, 39 clinical trials are slated to conclude within the next 90 days. This urgency is particularly relevant for healthy volunteers, as 12 of these rapidly closing studies are still actively seeking participants without specific health conditions. Individuals interested in contributing to medical advancements should explore these options promptly.

Currently, Madison, WI, is a robust center for medical research, with 537 clinical trials actively recruiting across 178 research facilities. This month, 7 new trials opened, a decrease compared to the 17 trials that launched in March 2026, but still offering fresh opportunities for participation.

Madison's Leading Research Hubs

The University of Wisconsin system continues to be the cornerstone of clinical research in Madison, hosting the vast majority of trials. These facilities are key destinations for individuals seeking to participate in medical research:

• University of Wisconsin (102 trials)
• University of Wisconsin Carbone Cancer Center - University Hospital (88 trials)
• University of Wisconsin Carbone Cancer Center - Eastpark Medical Center (54 trials)
• University of Wisconsin Carbone Cancer Center (34 trials)
• University of Wisconsin - Madison (31 trials)
• William S Middleton VA Medical Center (12 trials)

These institutions offer a broad spectrum of research, with a strong emphasis on oncology through the Carbone Cancer Center branches, alongside diverse medical fields at the broader University of Wisconsin facilities.

New Research Opportunities This April

April brings several notable new trials to Madison, including significant Phase 3 studies from major sponsors. These trials offer participants the chance to engage with cutting-edge treatments and diagnostic approaches across a range of health challenges.

• The University of Wisconsin, Madison is sponsoring NCT07532083, "Implementing AI-Assisted, Patient-Friendly Imaging Report Summaries to Enhance Oncology Care Delivery." This initiative, aiming for 2,000 participants, focuses on integrating AI tools to improve oncology care delivery by making imaging reports more accessible and understandable for patients.
• Memorial Sloan Kettering Cancer Center is sponsoring NCT07507643, "A Study of Methylprednisolone in People Having Liver Surgery." This Phase 3 study, designed for 750 participants, investigates whether receiving methylprednisolone before surgery can reduce common side effects like infections and shorten hospital stays.
• Incyte Corporation is launching NCT07522073, "A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma." This important Phase 3 oncology trial seeks 588 participants to evaluate the efficacy and safety of a new combination therapy for metastatic pancreatic cancer.

New trials this month are exploring a range of conditions, including epilepsy, hepatectomy, oncology, sleep, and solid tumors. Drug trials account for 4 of the new studies, followed by 2 device trials and 1 other type of study. Sponsors like Eli Lilly and Company and Pfizer also have new trials in the city this month.

Opportunities for Healthy Volunteers

For individuals without a specific medical condition, there are significant opportunities to contribute to medical science. 3 of the 7 new trials launched this month are actively seeking healthy volunteers. Across Madison, a total of 74 clinical trials are currently recruiting healthy participants, providing numerous avenues for those interested in supporting medical research.

Trials Closing Soon: Conditions Affected

Patients managing certain health conditions also face impending deadlines to join research. Trials focused on various cancers and other conditions are among those with limited time remaining for enrollment. Conditions with trials closing soon include:

• Healthy (2 trials)
• Stage iii pancreatic cancer ajcc v8 (2 trials)
• Breast cancer (2 trials)
• ACL injury (1 trial)
• Advanced or metastatic merkel cell carcinoma (1 trial)
• Analgesia (1 trial)
• Advanced breast cancer (1 trial)
• Anatomic stage iii breast cancer ajcc v8 (1 trial)
• B-cell acute lymphoblastic leukemia (1 trial)
• Brain metastasis (1 trial)

Broadening Your Search: Nearby Options

While Madison offers a substantial array of clinical trial opportunities, individuals may also find options in nearby communities within Wisconsin. Cities with active trials include Milwaukee (2 trials), Appleton (1 trial), and La Crosse (1 trial).

Who Can Participate?

Participation in clinical trials is open to a diverse range of individuals. Of the 7 new trials launched this month, 5 include older adults, ensuring that senior populations have ample opportunity to contribute to medical science. Additionally, 1 new trial is specifically designed for male participants. Academic institutions, particularly the University of Wisconsin, Madison, continue to play a vital role in the city's research ecosystem, sponsoring 3 of the new trials. Industry sponsors like Incyte Corporation and Pfizer are also driving significant research efforts.

As we move further into spring, the focus will remain on the ongoing enrollment in these significant Phase 3 trials and the continued exploration of new therapeutic strategies, with Madison's robust research community at the forefront of medical innovation.