Targeted Genomic Analysis of Blood and Tissue Samples From Patients With Cancer

Part of paid clinical trials in Brick, New Jersey.

Sponsor
Rutgers, The State University of New Jersey
Study ID
NCT02688517
Status
Recruiting
Apply to this trial

Conditions

  • Malignant Neoplasm

Eligibility Criteria

Sex
ALL
Age
1 Year - N/A
Healthy Volunteers
Not accepted

Interventions

  • Cytology Specimen Collection Procedure — OTHER
    Undergo collection of blood samples
  • Laboratory Biomarker Analysis — OTHER
    Correlative studies

Study Details

This research trial studies the use of targeted genomic analysis of blood and tissue samples from patients with cancer. Genomic sequencing is a laboratory method that is used to determine the entire genetic makeup of a specific organism or cell type. Genomic sequencing can be used to find changes in areas of the genome that may be important in the development of cancer. It may also help doctors improve ways to diagnose and treat patients with rare cancers with poor prognosis or lack of effective therapy.

Key Dates

Start date
Feb 28, 2013
Status verified
Apr 2026
Primary completion
May 31, 2030
Completion
May 31, 2030

Study Design

Enrollment
1,100 participants (estimated)

Arms

  • Arm: Ancillary-Correlative (genomic analysis)
    Previously collected tissue samples are analyzed for the presence of mutations via next generation sequencing. Patients may also undergo collection of blood samples for analysis of circulating cell-free DNA and circulating tumor cells.

Primary Outcome Measure

Frequencies of individual specific mutations and combinations of mutations of related pathway genes [ Time Frame: Up to 15 years ]

Central Contacts

  • Clinical Trials Office
    732-235-2465

Locations (11)

FacilityCityStateZIPSite coordinators
Ocean Medical CenterBrickNew Jersey08724-
Bayshore Community HospitalHolmdelNew Jersey07733-
RWJBarnabas Health - Jersey City Medical Center, Jersey CityJersey CityNew Jersey07302
Gregory Riedlinger
Southern Ocean County Medical CenterManahawkinNew Jersey08050-
Morristown Medical CenterMorristownNew Jersey07960-
Jersey Shore Medical CenterNeptune CityNew Jersey07753-
Rutgers Cancer Institute of New JerseyNew BrunswickNew Jersey08903
Clinical Trials Office
732-235-8675
Gregory Riedlinger (PRINCIPAL_INVESTIGATOR)
Riverview Medical CenterRed BankNew Jersey07701-
Riverview Medical Center/Booker Cancer CenterRed BankNew Jersey07701-
Overlook HospitalSummitNew Jersey07902-
University of Wisconsin Hospital and ClinicsMadisonWisconsin53792-

Find similar trials in Brick, NJ

By research site
Ocean Medical Center· Brick, NJBayshore Community Hospital· Holmdel, NJRWJBarnabas Health - Jersey City Medical Center, Jersey City· Jersey City, NJSouthern Ocean County Medical Center· Manahawkin, NJMorristown Medical Center· Morristown, NJJersey Shore Medical Center· Neptune City, NJ

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