Paid Clinical Trials in Massachusetts

Massachusetts has 3,587 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

3,587 clinical trials

↓ Download CSV

A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants

for Pneumococcal Disease

9 locations incl. Estero

Sponsor: Pfizer

Sex: All·Age: 42 Days - 98 Days·Accepts healthy volunteers

Code: NCT07573462·Phase 3·Recruiting

Apply to this trial

Application of the Personalized N-of-1 Trial Design in Patients With Rheumatoid Arthritis

for Arthritis, Rheumatoid

1 location in Boston

Sponsor: Tufts Medical Center

Sex: All·Age: 18+

Code: NCT06016517·Not Yet Recruiting

The Association Between Tau & GFAP and Postoperative Neurological Impairment in Patients Undergoing Cardiac Surgery

for Cardiac Surgery Requiring Cardiopulmonary Bypass

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: Up to 18

Code: NCT06899971·Not Yet Recruiting

Symptom Monitoring With Supported Feedback in Advanced Chronic Kidney Disease

for Chronic Kidney Disease (Stages 4 and 5)

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07186218·Not Yet Recruiting

Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder

for Alcohol Use Disorder

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 65

Code: NCT07296094·Phase 2·Not Yet Recruiting

Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis

for Psychosis

1 location in Belmont

Sponsor: Mclean Hospital

Sex: All·Age: 18 - 50

Code: NCT07503093·Not Yet Recruiting

Transcranial Ultrasonic Neuromodulation of Primary Visual Cortex and Primary Auditory Cortex in Humans

for Healthy Volunteers

1 location in Cambridge

Sponsor: Massachusetts Institute of Technology

Sex: All·Age: 21 - 55·Accepts healthy volunteers

Code: NCT07508722·Not Yet Recruiting

Falls Validation Study

for Intracranial Bleed

1 location in Boston

Sponsor: Dr. Kerstin de Wit

Sex: All·Age: 65+

Code: NCT07536906·Recruiting

Apply to this trial

Supporting Treatment Access and Recovery in Re-entry (STAR-R)

for Mental Health

2 locations incl. Northampton

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18+

Code: NCT07555145·Not Yet Recruiting

[64Cu]FBP8 PET for Early Detection of Intracardiac Thrombus in Amyloid Cardiomyopathy

for Cardiac Amyloidosis

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT07560306·Phase 3·Recruiting

Apply to this trial

Pharmacokinetic and Pharmacodynamic Investigations of Fetal Anesthesia During Maternal Fetal Surgery

for Fetal Anesthesia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: Female·Age: 13+·Accepts healthy volunteers

Code: NCT07571811·Not Yet Recruiting

An Intervention to Reduce Discrepancy in Everyday Preferences

for Dementia

1 location in Belmont

Sponsor: Mclean Hospital

Sex: All·Age: 55+

Code: NCT03577418·Not Yet Recruiting

Trans-nasal Endoscopy for Bariatric Patients

for Obesity

1 location in Boston

Sponsor: Christopher C. Thompson, MD, MSc

Sex: All·Age: 18 - 90

Code: NCT06200961·Recruiting

Apply to this trial

Pivotal Trial to Evaluate the Safety and Effectiveness of the P&F TricValve® Transcatheter Bicaval Valve System

for Tricuspid Valve Disease

35 locations incl. Birmingham

Sponsor: P+F Products + Features USA Inc.

Sex: All·Age: 18 - 85

Code: NCT06458907·Not Yet Recruiting

Necrosectomy With Cryotechnology for Accelerated Removal

for Pancreatic Necrosis

1 location in Boston

Sponsor: Christopher C. Thompson, MD, MSc

Sex: All·Age: 18+

Code: NCT06553651·Recruiting

Apply to this trial

At Home Wearable Sensors and Smartphone for Stroke Survivors With Upper Limb Motor Challenges.

for Stroke

1 location in Charlestown

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 18 - 80

Code: NCT06787729·Recruiting

Apply to this trial

Evaluation of Sex Differences in Glucose Metabolism in Response to Sleep Curtailment

for Sleep Deprivation

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 20 - 40·Accepts healthy volunteers

Code: NCT06809023·Not Yet Recruiting

Acute Hospital Care at Home for People Living With Dementia

for Emergency Department Visit

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06819852·Not Yet Recruiting

Study of Oral Food Challenge Biomarkers (SAFER)

for Allergy

10 locations incl. Little Rock

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12 Months - 17

Code: NCT07279467·Not Yet Recruiting

Chemotherapy With or Without IMD10 (Focused Ultrasound) in the Treatment of Borderline Resectable or Locally Advanced Pancreatic Cancer

for Pancreatic Cancer

3 locations incl. Boston

Sponsor: IMGT Co., Ltd.

Sex: All·Age: 18 - 85

Code: NCT07325214·Not Yet Recruiting

Gamma Light and Sound Stimulation in Schizophrenia

for Schizophrenia Spectrum Disorders

1 location in Cambridge

Sponsor: Massachusetts Institute of Technology

Sex: All·Age: 18 - 65

Code: NCT07342465·Not Yet Recruiting

Effects of Whole Fruit on Blood Sugar in People With Type 2 Diabetes

for Type 2 Diabetes

1 location in Boston

Sponsor: Harvard School of Public Health (HSPH)

Sex: All·Age: 18+

Code: NCT07376226·Not Yet Recruiting

Assessing the Efficacy and Safety of Photobiomodulation for the Treatment of Pruritus

for Pruritus

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07450716·EARLY_Phase 1·Not Yet Recruiting

Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech

for Stuttering, Developmental

1 location in Boston

Sponsor: Boston University Charles River Campus

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07459803·Not Yet Recruiting

WEARABLE-BP: Wearable Everyday Automated Readings to Enable Assessment of Blood Pressure Control

for Hypertension (HTN)

1 location in Boston

Sponsor: Aktiia SA

Sex: All·Age: 21 - 85

Code: NCT07523269·Recruiting

Apply to this trial

A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study

for Patient-Reported Outcome Measures (PROMs)

14 locations incl. Stanford

Sponsor: Carelon Research

Sex: All·Age: 12 - 17

Code: NCT07525843·Recruiting

Apply to this trial

A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolar I Disorder

for Bipolar I Disorder

1 location in Boston

Sponsor: Alzamend Neuro, Inc.

Sex: All·Age: 18 - 65

Code: NCT07540338·Phase 1, Phase 2·Recruiting

Apply to this trial

Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression

for Treatment Resistant Depression (TRD)

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07563868·Recruiting

Apply to this trial

Observational Study of Adults and Adolescents With Erythropoietic Protoporphyria (EPP) and X-linked Porphyria (XLP)

for Erythropoietic Protoporphyria (EPP)

5 locations incl. Boston

Sponsor: Portal Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT07567131·Recruiting

Apply to this trial

Advanced Imaging to Assess the Effect of Immunosuppression on Progressive Fibrosis

for Interstitial Lung Disease

1 location in Boston

Sponsor: Peter Caravan

Sex: All·Age: 18 - 80

Code: NCT07572383·Phase 2·Recruiting

Apply to this trial

A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder

for Depressive Disorder, Major

Drug: Seltorexant

10 locations incl. Walnut Creek

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 74

Code: NCT07573176·Phase 3·Recruiting

Apply to this trial

Prenatally-initiated Psychological Intervention for Mothers of Infants With Congenital Heart Disease (CHD)

for Congenital Heart Disease (CHD)

17 locations incl. Phoenix

Sponsor: Carelon Research

Sex: All·Age: 18+

Code: NCT07582861·Not Yet Recruiting

Androgen-responsive POSLUMA-guided Intra-prostatic Boost

for Intermediate Risk Prostate Cancer

4 locations incl. Boston

Sponsor: Martin T. King, MD, PhD

Sex: Male·Age: 18+

Code: NCT07393867·Phase 2·Recruiting

Apply to this trial

guideSEQ: Genomic Understanding, Impact, Decision & Ethics in Prenatal Sequencing

for Prenatal Genetic Diagnosis

3 locations incl. Boston

Sponsor: Columbia University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07610590·Recruiting

Apply to this trial

Impact of Clinician-administered Vaginal Live Biotherapeutic Product

for Bacterial Vaginosis

1 location in Boston

Sponsor: Caroline Mitchell

Sex: Female·Age: 18 - 40

Code: NCT07305844·EARLY_Phase 1·Enrolling By Invitation

Study of Remimazolam for Cataract Surgery

for Cataract Surgery Anesthesia

1 location in Boston

Sponsor: Fred E, Shapiro

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT07325227·Phase 4·Not Yet Recruiting

Phase 2 Study to Assess the Safety and Efficacy of ANG003

for Exocrine Pancreatic Insufficiency (EPI)

26 locations incl. Long Beach

Sponsor: Anagram Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT07450547·Phase 2·Recruiting

Apply to this trial

An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)

for Pulmonary Arterial Hypertension

2 locations incl. Louisville

Sponsor: Inhibikase Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07365332·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 2

for Narcolepsy Type 2

Drug: ALKS 2680

13 locations incl. Boulder

Sponsor: Alkermes, Inc.

Sex: All·Age: 18 - 70

Code: NCT07502443·Phase 3·Recruiting

Apply to this trial

Flo Digital Contraceptive Study

for Contraception Use

1 location in Boston

Sponsor: Flo Health Inc.

Sex: Female·Age: 18+

Code: NCT07630064·Recruiting

Apply to this trial