Effects of Whole Fruit on Blood Sugar in People With Type 2 Diabetes

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Harvard School of Public Health (HSPH)
Study ID
NCT07376226
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Whole Fruit — OTHER
    Participants will consume a large amount of whole fruit for 17 weeks. During the first 6.5 weeks, participants will gradually increase the amount of whole fruit they eat by 5% every 5 days. Once they reach 50% of their calories as whole fruit, they will continue to eat 50% fruit for the remaining 10.5 weeks of the study. This is a controlled feeding study, so participants will consume fruit prepared in a metabolic kitchen. The fruit will consist of fresh fruit, dried fruit, and frozen fruit blended into smoothies. To demonstrate compliance, participants will video-record themselves eating the provided fruit. All participants will receive the same dietary intervention. Participants will otherwise continue their usual diet and lifestyle habits.

Study Details

This study will determine the effects of consuming whole fruit on blood sugar control, liver fat, and cardiovascular health in adults with type 2 diabetes who are not treated with insulin.

Key Dates

Start date
Apr 30, 2026
Status verified
Jan 2026
Primary completion
Oct 31, 2027
Completion
Apr 30, 2028

Study Design

Enrollment
25 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Whole Fruit
    Participants will consume a large amount of whole fruit, constituting 50% of total calories.

Primary Outcome Measure

Mean 24-hour Glucose Levels [ Time Frame: Change from baseline to week 17 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Harvard T. H. Chan School of Public HealthBostonMassachusetts02115
Kathleen Johnson
[email protected]
617-998-6333
Courtney M Peterson, PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Boston, MA

By condition
Type 2 diabetes
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Harvard T. H. Chan School of Public Health· Boston, MA

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