Chemotherapy With or Without IMD10 (Focused Ultrasound) in the Treatment of Borderline Resectable or Locally Advanced Pancreatic Cancer

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
IMGT Co., Ltd.
Study ID
NCT07325214
Status
Not Yet Recruiting

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Conditions

  • Borderline Resectable Pancreatic Cancer
  • Locally Advanced Pancreatic Cancer
  • Pancreatic Cancer

Eligibility Criteria

Sex
ALL
Age
18 Years - 85 Years
Healthy Volunteers
Not accepted

Interventions

Study Details

The purpose of this Interventional clinical trial is to evaluate safety and efficacy of 'IMD10 (focused ultrasound)' in the treatment of borderline resectable pancreatic cancer or locally advanced pancreatic cancer.

Key Dates

Start date
Apr 30, 2026
Status verified
Jan 2026
Primary completion
Aug 31, 2029
Completion
Aug 31, 2029

Study Design

Enrollment
136 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Experimental group
    The experimental group receives chemotherapy regimen \[irinotecan hydrochloride, oxaliplatin, fluorouracil (5-FU) and leucovorin\] in combination with IMD10.
  • Active Comparator: Control group
    The control group receives a chemotherapy regimen \[irinotecan hydrochloride, oxaliplatin, fluorouracil (5-FU) and leucovorin\] alone, the same regimen administered to the experimental group.

Primary Outcome Measure

Overall Survival [ Time Frame: From the date of the first trial participant's randomization to 24 months after the last trial participant's randomization ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
Brigham and Women's HospitalBostonMassachusetts02115
Jiping Wang, M.D.
University of Texas Health Science Center at San AntonioSan AntonioTexas78229
Richard Tuli, M.D.
University of Virginia Medical CenterCharlottesvilleVirginia22908
Allan Tsung, M.D.

Find similar trials in Boston, MA

By condition
Pancreatic cancer
By specialty
OncologyGI oncology
By research site
Brigham and Women's Hospital· Boston, MAUniversity of Texas Health Science Center at San Antonio· San Antonio, TXUniversity of Virginia Medical Center· Charlottesville, VA

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