Clinical Trials at University of Southern California

As of June 2026, 100 paid clinical trials are recruiting at University of Southern California, located at 1441 EASTLAKE AVE, LOS ANGELES, CA 90089-0112, phone (323) 865-3000 in Los Angeles, California. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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100 clinical trials at University of Southern California

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Simvastatin Treatment to Improve Patient-reported Outcomes in Patients With Chronic Pancreatitis

for Recurrent Acute Pancreatitis

5 locations incl. Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18 - 75

Code: NCT05771675·EARLY_Phase 1·Recruiting

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Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06401577·Recruiting

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Music-Based Interventions, Aging, Alzheimer's Disease

for Speech Perception

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06152211·Recruiting

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Phase I, Dose-Escalation Study of Dihydromyricetin (DHM) to Treat Alcohol-Associated Liver Disease

for Alcohol-Related Disorders

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT05623501·Phase 1·Not Yet Recruiting

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

for Ovarian Cancer

10 locations incl. Los Angeles

Sponsor: Nammi Therapeutics Inc

Sex: All·Age: 18+

Code: NCT06582017·Phase 1·Recruiting

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eMOTION: Examining Affective Mechanisms in Physical Activity Engagement

for Physical Inactivity

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06570642·Recruiting

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Novel Multimodal Neural, Physiological, and Behavioral Sensing and Machine Learning for Mental States

for No Condition

2 locations incl. Downey

Sponsor: University of Southern California

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07110688·Recruiting

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A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)

for Generalized Myasthenia Gravis

Drug: Telitacicept

20 locations incl. Los Angeles

Sponsor: Vor Biopharma

Sex: All·Age: 18+

Code: NCT06456580·Phase 3·Recruiting

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Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients With Cystic Fibrosis

for Cystic Fibrosis

3 locations incl. Los Angeles

Sponsor: SpliSense Ltd.

Sex: All·Age: 18+

Code: NCT06429176·Phase 2·Recruiting

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Endovascular AAA Intervention Using the GORE® EXCLUDER® Conformable AAA Endoprosthesis or Iliac Branch Endoprosthesis

for AAA - Abdominal Aortic Aneurysm

56 locations incl. Little Rock

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06218875·Recruiting

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A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast

for Idiopathic Pulmonary Fibrosis

Drug: Nerandomilast

58 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06238622·Phase 3·Recruiting

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A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

for Pulmonary Fibrosis

59 locations incl. Birmingham

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06329401·Phase 2·Recruiting

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Regulation of Affect and Physiology in Depression

for Major Depressive Disorder

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18 - 27·Accepts healthy volunteers

Code: NCT06345859·Phase 2·Recruiting

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Personalized Health Self-Management Training for Colorectal Cancer Survivors

for Colorectal Cancer

2 locations incl. Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT05984589·Recruiting

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Abuse Liability and Appeal of Oral Nicotine Products

for Nicotine Dependence

2 locations incl. Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 21 - 25·Accepts healthy volunteers

Code: NCT06506162·Recruiting

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Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic Insufficiency

for Exocrine Pancreatic Insufficiency

6 locations incl. Los Angeles

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT06477159·Phase 4·Recruiting

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Pneumatic Compression vs Blood Flow Restriction for Muscle Recovery

for Delayed Onset Muscle Soreness

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18 - 30·Accepts healthy volunteers

Code: NCT06815367·Recruiting

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National Liver Cancer Screening Trial

for Carcinoma, Hepatocellular

18 locations incl. Los Angeles

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 85

Code: NCT06084234·Phase 4·Recruiting

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Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

for T-cell Lymphoma

10 locations incl. Scottsdale

Sponsor: SciTech Development, Inc.

Sex: All·Age: 18+

Code: NCT04234048·Phase 1·Recruiting

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Zenith® Fenestrated+ Clinical Study

for Aortic Aneurysm, Abdominal

32 locations incl. Birmingham

Sponsor: Cook Research Incorporated

Sex: All·Age: 18+

Code: NCT04875429·Recruiting

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Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

for Open tíbia Fracture

29 locations incl. Chandler

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+

Code: NCT05615844·Phase 3·Recruiting

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Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD

for Neuromyelitis Optica

10 locations incl. Los Angeles

Sponsor: Ad scientiam

Sex: All·Age: 18+

Code: NCT05566769·Recruiting

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Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

for Diffuse Astrocytoma, IDH-Mutant

6 locations incl. Beverly Hills

Sponsor: Neonc Technologies, Inc.

Sex: All·Age: 18+

Code: NCT06047379·Phase 1, Phase 2·Recruiting

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A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

for Advanced Solid Tumor

14 locations incl. Los Angeles

Sponsor: Volastra Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05902988·Phase 1, Phase 2·Recruiting

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KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

for Solid Tumors With HRAS Alterations

22 locations incl. Phoenix

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06026410·Phase 1·Recruiting

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Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth In/near Infected Bone Cavities

for Periprosthetic Joint Infections

12 locations incl. Los Angeles

Sponsor: Elute, Inc.

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT05361941·Recruiting

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DFC 004 Biomarkers for Active Diabetic Foot Ulcers

for Diabetic Foot Ulcer

8 locations incl. Tucson

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06104969·Recruiting

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Alzheimer's Disease Neuroimaging Initiative 4

for Mild Cognitive Impairment

59 locations incl. Birmingham

Sponsor: University of Southern California

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05617014·Enrolling By Invitation

G7 Freedom Constrained Vivacit-E Liners

for Osteoarthritis, Hip

10 locations incl. Birmingham

Sponsor: Zimmer Biomet

Sex: All·Age: 18 - 80

Code: NCT05587244·Enrolling By Invitation

Modernizing Perinatal Syphilis Testing

for Syphilis

9 locations incl. Los Angeles

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: Up to 45

Code: NCT06082453·Recruiting

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Feasibility of an In-home Standing and Walking Intervention for Infants With and at High Risk of Cerebral Palsy

for Cerebral Palsy

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 5 Months - 2

Code: NCT05781438·Recruiting

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iMmune SignAtures and Clinical outComes in AP

for Acute Pancreatitis

5 locations incl. Los Angeles

Sponsor: Ohio State University

Sex: All·Age: 18 - 75

Code: NCT05878236·Recruiting

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A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

for Colorectal Neoplasms

128 locations incl. Glendale

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT05253651·Phase 3·Recruiting

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Social Influences on Sensorimotor Integration of Speech Production and Perception During Early Vocal Learning

for Sensorineural Hearing Loss

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 7 Months - 24 Months·Accepts healthy volunteers

Code: NCT05634356·Recruiting

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Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors

for Advanced Cancer

7 locations incl. Phoenix

Sponsor: Qurient Co., Ltd.

Sex: All·Age: 18+

Code: NCT05394103·Phase 1, Phase 2·Recruiting

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A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

for Advanced or Metastatic Colorectal Cancer

Drug: Amivantamab

14 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05379595·Phase 1, Phase 2·Recruiting

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NEO100 and High-Grade Meningioma

for Residual, Progressive or Recurrent Grade II or III Meningioma

3 locations incl. Los Angeles

Sponsor: Neonc Technologies, Inc.

Sex: All·Age: 12+

Code: NCT05023018·Phase 2·Recruiting

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Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer

for Non-Muscle Invasive Bladder Neoplasms

25 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05316155·Phase 1, Phase 2·Recruiting

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Improving Father-Child and Father-Partner Relationships Among Black and Hispanic Fathers

for Parent-Child Relations

1 location in Los Angeles

Sponsor: University of Southern California

Sex: Male·Age: 18 - 60

Code: NCT05214898·Enrolling By Invitation

Model-based Electrical Brain Stimulation

for Medication Refractory Epilepsy Patients With Electrodes Already Implanted Based on Clinical Criteria for Standard Monitoring

2 locations incl. Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT05327387·Recruiting

Apply to this trial