Pneumatic Compression vs Blood Flow Restriction for Muscle Recovery

Part of paid clinical trials in Los Angeles, California.

Sponsor
University of Southern California
Study ID
NCT06815367
Status
Recruiting
Apply to this trial

Conditions

  • Delayed Onset Muscle Soreness

Eligibility Criteria

Sex
ALL
Age
18 Years - 30 Years
Healthy Volunteers
Accepted

Interventions

  • Pneumatic Compression — DEVICE
    Following downhill running protocol, participants will complete 20 minutes of pneumatic compression at 100 mmHg.
  • Blood Flow Restriction — DEVICE
    Following the downhill running protocol, participants will complete 4 rounds of treatment: 3 minutes at 100% resting limb occlusion pressure, 2 minutes of 0% resting limb occlusion pressure.

Study Details

Both BFR and intermittent pneumatic compression are purported to decrease symptoms associated with exercise induced muscle damage (EIMD) that cause delayed onset muscle soreness (DOMS). Blood flow restriction relies on applying pressurized cuffs to the most proximal portion of the limb. Another form of recovery often relied upon is pneumatic compression. The mechanism by which pneumatic compression works is similar to that of a massage, whereby the device progressively increases the pressure on a portion of the limb before releasing and moving further up the limb.The purpose of this study is determine whether BFR or pneumatic compression can be used to decreased DOMS which may indicate enhanced recovery.

Key Dates

Start date
Jan 15, 2024
Status verified
Aug 2025
Primary completion
Dec 1, 2025
Completion
May 1, 2026

Study Design

Enrollment
33 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • No Intervention: Control
    The participants will be asked to refrain from exercise 24 hours prior to and following the exercise. Participants will complete all pre-exercise tests (DOMS, CMJ, MVIC). The exercise consists of running on a treadmill situated at a -10% grade at 9 km/hr (5.59 mph) for 20 minutes. This is proceeded and followed by 5 minute warm-up/cool-down periods. Those that are allocated to the "control" group, will not receive treatment after the downhill running protocol.
  • Experimental: Pneumatic compression
    The participants will be asked to refrain from exercise 24 hours prior to and following the exercise. Participants will complete all pre-exercise tests (DOMS, CMJ, MVIC). The exercise consists of running on a treadmill situated at a -10% grade at 9 km/hr (5.59 mph) for 20 minutes. This is proceeded and followed by 5 minute warm-up/cool-down periods. Those allocated to the "pneumatic compression" group will receive 20 minutes of pneumatic compression at 100 mmHg.
  • Experimental: Blood flow restriction
    The participants will be asked to refrain from exercise 24 hours prior to and following the exercise. Participants will complete all pre-exercise tests (DOMS, CMJ, MVIC). The exercise consists of running on a treadmill situated at a -10% grade at 9 km/hr (5.59 mph) for 20 minutes. This is proceeded and followed by 5 minute warm-up/cool-down periods. Those allocated to the "BFR" group will receive 4 rounds of treatment: 3 minutes will be spent at 100% of resting limb occlusion pressure, followed by 2 minutes of 0% occlusion.

Primary Outcome Measure

Counter Movement Jump Height [ Time Frame: Immediately before and immediately after exercise, immediately after treatment, 24-hours post treatment. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Southern CaliforniaLos AngelesCalifornia90033
Bailey McLagan
323-442-2498

Find similar trials in Los Angeles, CA

By research site
University of Southern California· Los Angeles, CA

Related Studies