Paid Clinical Trials in Lexington, KY

As of June 2026, 508 paid clinical trials are recruiting in Lexington, Kentucky. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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508 clinical trials

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Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

for Ampulla of Vater Carcinoma

309 locations incl. Phoenix

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07283939·Recruiting

Apply to this trial

A Study of Brenipatide in Participants With Opioid Use Disorder

for Opioid Use Disorder

Drug: Brenipatide

38 locations incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07420283·Phase 2·Recruiting

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A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

for Overweight

Drug: Eloralintide

54 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07392190·Phase 3·Recruiting

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Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes

for Metastatic Ewing Sarcoma

17 locations incl. Birmingham

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 1+

Code: NCT07194044·Phase 1·Recruiting

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Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for Gastric Cancer

Drug: Sonesitatug vedotin

77 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07431281·Phase 3·Recruiting

Apply to this trial

Tasting Plant Forward Meals

for Dietary Exposure

1 location in Lexington

Sponsor: Sara Maksi

Sex: All·Age: 18 - 25·Accepts healthy volunteers

Code: NCT07202988·Recruiting

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Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for Advanced Endometrial Carcinoma

Drug: Bevacizumab

211 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07198074·Phase 3·Recruiting

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Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy

for Colorectal Cancer Metastatic

1 location in Lexington

Sponsor: Michael J Cavnar, MD

Sex: All·Age: 18 - 99

Code: NCT07201519·Phase 2·Recruiting

Apply to this trial

Colchicine's Effect on Inflammatory Markers

for Colchicine

1 location in Lexington

Sponsor: Ayesha Ather

Sex: All·Age: 18 - 99

Code: NCT07287345·Phase 4·Recruiting

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Non-Abstinence Outcomes in Methamphetamine Use Disorder

for Methamphetamine Use Disorder

1 location in Lexington

Sponsor: William Stoops

Sex: All·Age: 18+

Code: NCT07226596·Recruiting

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A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

for Large B-cell Lymphoma

38 locations incl. Gilbert

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT07188558·Phase 3·Recruiting

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Home-based Under Mattress Monitor for OSA

for Obstructive Sleep Apnea (OSAS)

1 location in Lexington

Sponsor: Isabel Moreno Hay

Sex: All·Age: 18 - 80

Code: NCT07186725·Recruiting

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A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

for Metastatic Non-small Cell Lung Cancer With MTAP Deletion

Drug: Navlimetostat

42 locations incl. Anchorage

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07063745·Phase 2, Phase 3·Recruiting

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A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

for Carcinoma, Transitional Cell

60 locations incl. Huntsville

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07218380·Phase 3·Recruiting

Apply to this trial

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

for Miscellaneous Neoplasm, Nos

231 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07091617·Recruiting

Apply to this trial

Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody

for Clostridioides Difficile Infection

42 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07285213·Phase 2·Recruiting

Apply to this trial

Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

for Neonatal Opioid Withdrawal Syndrome

22 locations incl. Birmingham

Sponsor: HELP for NOWS Consortium

Sex: All·Age: 0 Minutes+

Code: NCT07278375·Recruiting

Apply to this trial

Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.

for GEP-NET

7 locations incl. Iowa City

Sponsor: RayzeBio, Inc.

Sex: All·Age: 18+

Code: NCT07165132·Phase 1·Recruiting

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A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

for Squamous Cell Carcinoma of Head and Neck

Drug: Amivantamab

41 locations incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07276399·Phase 3·Recruiting

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A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors

for SST2-positive Neuroendocrine Neoplasms

20 locations incl. Phoenix

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT07129252·Phase 1, Phase 2·Recruiting

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Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

for Muscle Invasive Bladder Urothelial Carcinoma

143 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07061964·Phase 2·Recruiting

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A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

for Small Cell Lung Cancer

Drug: Atezolizumab

9 locations incl. New Haven

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07155174·Phase 2·Recruiting

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Shared Decision Making to Treat Or Prevent (STOP) HIV in Justice Populations (R33)

for Substance Use Disorders

4 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT07223398·Recruiting

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A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for Epithelial Ovarian Cancer

64 locations incl. Birmingham

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06890338·Phase 2·Recruiting

Apply to this trial

Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

for Carcinoid Syndrome

17 locations incl. Gilbert

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT07087054·Phase 3·Recruiting

Apply to this trial

IOA Preventing Occlusal Changes With MAD Use

for Sleep Related Breathing Disorder

1 location in Lexington

Sponsor: Isabel Moreno Hay

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07103941·Recruiting

Apply to this trial

Efficacy and Clinical Feasibility of the Ankle Muscle Power (AMP) Program for Return to Duty After an Ankle Fracture

for Ankle Fractures

1 location in Lexington

Sponsor: Brian W. Noehren

Sex: All·Age: 18 - 50

Code: NCT07173088·Recruiting

Apply to this trial

Cocaine and Pentoxifylline (BED IN 47)

for Cocaine Use Disorder

1 location in Lexington

Sponsor: William Stoops

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07086794·EARLY_Phase 1·Recruiting

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A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial Fibrillation

for Atrial Fibrillation (AF)

32 locations incl. Birmingham

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07187115·Recruiting

Apply to this trial

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

148 locations incl. Loma Linda

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting

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Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for Locally Advanced Cervical Adenocarcinoma

260 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07061977·Phase 3·Recruiting

Apply to this trial

Mitigating the Disinhibiting Effects of Alcohol With Transcranial Magnetic Stimulation

for Alcohol Risk Behaviors

1 location in Lexington

Sponsor: Michael J. Wesley, PhD

Sex: All·Age: 21 - 29·Accepts healthy volunteers

Code: NCT07188376·Recruiting

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A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

for Ovarian Neoplasms

82 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213804·Phase 3·Recruiting

Apply to this trial

A Community Cardiovascular Disease Risk Reduction Program in Older Adults Engaged in Congregate Nutrition Services (CAN-DO)

for Cardiovascular Risk Reduction

1 location in Lexington

Sponsor: Martha Biddle

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07168044·Enrolling By Invitation

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for Colorectal Cancer Stage II

376 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07018869·Phase 3·Recruiting

Apply to this trial

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

for Metabolic Dysfunction-Associated Steatotic Liver Disease

140 locations incl. Tuscaloosa

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07165028·Phase 3·Recruiting

Apply to this trial

Neurocognitive Ankle Training for Instability to Optimize Neuromusculoskeletal Outcomes (NATION)

for Chronic Ankle Instability

2 locations incl. Lexington

Sponsor: Womack Army Medical Center

Sex: All·Age: 18 - 44

Code: NCT06527287·Recruiting

Apply to this trial

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

for Muscle Invasive Bladder Urothelial Carcinoma

211 locations incl. Fort Smith

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT07097142·Phase 3·Recruiting

Apply to this trial

Closed Loop and Education for Hypoglycemia Awareness Restoration

for Diabetes Mellitus, Type 1

5 locations incl. La Jolla

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06325202·Recruiting

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A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

for Cachexia

Drug: ponsegromab

72 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06989437·Phase 2, Phase 3·Recruiting

Apply to this trial