Non-Abstinence Outcomes in Methamphetamine Use Disorder

Part of paid clinical trials in Lexington, Kentucky.

Sponsor
William Stoops
Study ID
NCT07226596
Status
Recruiting
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Conditions

  • Methamphetamine Use Disorder

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Contingency Management — BEHAVIORAL
    Subjects will receive payments for providing methamphetamine negative urine samples.

Study Details

Reduced drug use is a clinically meaningful target for treatment development, but few studies have evaluated the positive impacts produced by this behavioral change, preventing adoption of this endpoint in clinical trials. The proposed research will fill that critical knowledge gap by demonstrating the biopsychosocial benefits of reduced methamphetamine use. These data will be used to change current accepted methamphetamine treatment endpoints and accelerate identification of therapies for methamphetamine use disorder.

Key Dates

Start date
Jan 14, 2026
Status verified
Jun 2026
Primary completion
Jan 4, 2031
Completion
Jan 4, 2031

Study Design

Enrollment
300 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • No Intervention: Control Group
    This group will receive payment for providing urine samples throughout the trial.
  • Experimental: Contingency Management Group
    This group will receive payment for providing methamphetamine negative urine samples throughout the trial.

Primary Outcome Measure

Mean Arterial Pressure [ Time Frame: At baseline. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Psychopharmacology of Addiction LaboratoryLexingtonKentucky40507
William W Stoops, PhD
[email protected]
859-257-5388

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By research site
Psychopharmacology of Addiction Laboratory· Lexington, KY

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