Deep TMS of Neural Circuits Associated With Stimulant Use Disorder

Part of paid clinical trials in Palo Alto, California.

Sponsor
Stanford University
Study ID
NCT06578429
Status
Recruiting
Apply to this trial

Conditions

  • Methamphetamine Use Disorder
  • Transcranial Magnetic Stimulation

Eligibility Criteria

Sex
ALL
Age
25 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Deep Transcranial Magnetic Stimulation (dTMS) H4 coil - Active — DEVICE
    The study will utilize the H4 coil to administer active Deep Transcranial Magnetic Stimulation (dTMS) to the bilateral insula, a core salience network node.
  • Deep Transcranial Magnetic Stimulation (dTMS) H4 coil - Sham — DEVICE
    The study will utilize an identical protocol using the H4 coil to administer a sham condition.

Study Details

This study aims to evaluate the efficacy of deep transcranial magnetic stimulation (dTMS) as a treatment for Veterans with a methamphetamine use disorder (MUD).

Key Dates

Start date
Mar 15, 2025
Status verified
Sep 2025
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Active dTMS
    Participants will receive 30 active dTMS treatments, administered 3 times per day over 10 consecutive business days. Each treatment visit will last approximately 30 minutes in total.
  • Sham Comparator: Sham dTMS
    Participants will receive 30 sham dTMS sessions, administered 3 times per day over 10 consecutive business days. Each treatment visit will last approximately 30 minutes in total.

Primary Outcome Measure

Insula Function [ Time Frame: 1-4 days post-treatment ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
VA Palo Alto Health Care SystemPalo AltoCalifornia94304
Eileen Grace Fischer, BS
[email protected]
210-993-2065
Samantha Ward, BS
[email protected]
650-493-5000

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By research site
VA Palo Alto Health Care System· Palo Alto, CA

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