Paid Clinical Trials in Kentucky
Kentucky has 1,052 paid clinical trials enrolling now across cities including Louisville, Lexington and Edgewood. Search by condition, age, or phase to find compensated research studies accepting participants near you.
Research sites in Kentucky include National Cancer Institute (NCI), University of Louisville and AstraZeneca, running studies across oncology, cardiology, neurology, and more. The most actively recruiting conditions are Heart Failure, Breast Cancer, Obesity, Ovarian Cancer — browse the full list or use the filters to match your diagnosis. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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1,052 clinical trials
↓ Download CSVTesting the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma
A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum Disorder
MeDex: No Perioperative Dexamethasone in Brain Metastases
The Impact of Cobenfy Maintenance on Cocaine's Effects
Training Induced Muscle-Adipose EV Communication
Feasibility, Acceptability, and Preliminary Efficacy of an HIV Prevention Intervention for Older Black Women
Oral Mucosa Wound Healing After Gingival Recession Treatment in Diabetic Patients. A Clinical Study.
Gastric Electrical Stimulation for Abdominal Pain in Patients With Gastroparesis
Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans Study
A Phase Ib Study of VK-2019 in Patients With Relapsed or Refractory EBV+ Diffuse Large B-cell Lymphomas (DLBCL)
Gamification Effects on the 6-Minute Walk Test in Children
Mitral Valve Repair With the Chord-X System: A Long Term Evaluation
Biomarkers in Management of Post Partum Preeclampsia
Palatal Wound Healing After Free Gingival Graft Harvest in Diabetic Patients: A Clinical Trial
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
Testing STAR and TextSTAR: A Randomized Controlled Trial
Repeated CBD Administration and Cannabis Outcomes
A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity
Fluorescent Probe for Assessment of Renal Elimination
Comparing Acupuncture vs. Sham Acupuncture for the Management of Hot Flashes in Prostate Cancer Patients Receiving Hormone Therapy
Massage, Oncology, Pain, Anxiety, Feasibility
CleaRRAflow: Isotonic Solution vs. TPA for IVH Clearance
Parents' HPV Stories
PITCH - Impacting Hereditary Cancer Testing
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Kentucky Women's Justice Community Overdose Innovation Network - Phase II
Cervical Plexus Hydrodissection With D5W Versus NS for Treatment-Resistant PTSD
AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)
A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants
MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease
A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer
Time-restricted Eating for Patients With Type 2 Diabetes
An Aging Healthy Intervention for Older Adults Delivered by Community Health Workers in Senior Centers: A Clinical Trial
Methadone for Post-operative Spine Surgery
A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study
Prenatally-initiated Psychological Intervention for Mothers of Infants With Congenital Heart Disease (CHD)
About research studies in Kentucky
Kentucky has approximately 1,052 recruiting research studies across a wide range of therapeutic areas. Kentucky hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Common conditions studied in Kentucky
- Heart Failure (20 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Breast Cancer (16 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Obesity (14 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Ovarian Cancer (13 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
- Acute Myeloid Leukemia (11 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Head and Neck Squamous Cell Carcinoma (10 active studies). Recruiting Head and Neck Squamous Cell Carcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Kentucky
- National Cancer Institute (NCI)
- University of Louisville
- AstraZeneca
- Merck Sharp & Dohme LLC
- Eli Lilly and Company
Local regulations and guidelines
Clinical trials in Kentucky are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Kentucky research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Kentucky. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Kentucky
Hipa.ai aggregates every recruiting study in Kentucky from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Kentucky?
There are approximately 1,052 recruiting clinical trials in Kentucky listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Kentucky pay participants?
Most recruiting trials in Kentucky compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Kentucky?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Kentucky?
The most common conditions under active study in Kentucky include Heart Failure (20), Breast Cancer (16), Obesity (14), Ovarian Cancer (13), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Kentucky?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Kentucky on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Kentucky?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.