Paid Clinical Trials in Kentucky

Kentucky has 1,052 paid clinical trials enrolling now across cities including Louisville, Lexington and Edgewood. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,052 clinical trials

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A Phase 1 Study of ZE50-0134 in Relapsed and Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Select Low-grad Lymphomas

for CLL / SLL

4 locations incl. Louisville

Sponsor: Lomond Therapeutics Holdings, Inc.

Sex: All·Age: 18+

Code: NCT06708897·Phase 1·Recruiting

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Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer

for Extensive Stage Small Cell Lung Cancer (ES-SCLC)

19 locations incl. Hot Springs

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06801834·Phase 3·Recruiting

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A Study to Compare the Efficacy and Safety of TachoSil and Surgicel Original as an Adjunct to Control Mild to Moderate Soft Tissue Bleeding During Surgery

for Hemorrhage

9 locations incl. Torrance

Sponsor: Corza Medical GmbH

Sex: All·Age: 1 Month+

Code: NCT06664775·Phase 3·Recruiting

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IRONICA: IRON Repletion In Heart Failure - A Comparison of Oral and IV Approaches

for Heart Failure

1 location in Bowling Green

Sponsor: Syed Hamza Mufarrih

Sex: All·Age: 18 - 100

Code: NCT07053475·Phase 4·Recruiting

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Opioid Drug Interaction Study

for Drug Interactions

1 location in Lexington

Sponsor: Shanna Babalonis, PhD

Sex: All·Age: 18 - 55

Code: NCT06757140·Phase 1, Phase 2·Recruiting

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A Phase 1 Dose Escalation Study of ZG006 in Patients With Small Cell Lung Cancer

for Small Cell Lung Cancer

6 locations incl. Orange

Sponsor: Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Sex: All·Age: 18 - 75

Code: NCT06592638·Phase 1·Recruiting

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A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

for Advanced Solid Tumors Cancer

11 locations incl. Los Angeles

Sponsor: Nimbus Wadjet, Inc.

Sex: All·Age: 18 - 99

Code: NCT06898450·Phase 1, Phase 2·Recruiting

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A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

for Non-small Cell Lung Cancer

5 locations incl. Lexington

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06731907·Phase 2·Recruiting

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MagDI U.S. Registry

for Anastomosis, Surgical

5 locations incl. Ventura

Sponsor: GT Metabolic Solutions, Inc.

Sex: All·Age: 22+

Code: NCT06928545·Recruiting

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A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting

for Ulcerative Colitis

100 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18 - 80

Code: NCT06581328·Phase 4·Recruiting

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2024 Tirzepatide-Bariatric Surgery

for Obesity and Obesity-related Medical Conditions

Drug: Tirzepatide

1 location in Lexington

Sponsor: Marlene Starr

Sex: All·Age: 18+

Code: NCT06721507·Phase 4·Recruiting

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A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects

for Elevated Blood Pressure

5 locations incl. Valley Village

Sponsor: Zona Health, Inc

Sex: All·Age: 22+

Code: NCT06843577·Recruiting

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Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY3537982

85 locations incl. Huntsville

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06890598·Phase 3·Recruiting

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Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

for Advanced Solid Tumor

Drug: AI-081

19 locations incl. Birmingham

Sponsor: OncoC4, Inc.

Sex: All·Age: 18+

Code: NCT06635785·Phase 1, Phase 2·Recruiting

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Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain

for Chronic Low-back Pain

17 locations incl. Flagstaff

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT06827262·Recruiting

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Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

for Asthma

55 locations incl. Bakersfield

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT06932263·Phase 2·Recruiting

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A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

for Chronic Obstructive Pulmonary Disease (COPD)

68 locations incl. Cullman

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06878261·Phase 3·Recruiting

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Oncology Legal Navigation Study

for Financial Stress

1 location in Lexington

Sponsor: Jean Edward

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT07443839·Recruiting

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

76 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting

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Safety and Immunogenicity Study of Revaccination With SCB-1019T in Healthy Adults

for RSV Infection

5 locations incl. Phoenix

Sponsor: Clover Biopharmaceuticals USA, LLC

Sex: All·Age: 60 - 85·Accepts healthy volunteers

Code: NCT06843317·Phase 1·Recruiting

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A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

for Psoriasis

Drug: Tirzepatide

40 locations incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06857942·Phase 4·Recruiting

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Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

for Advanced Malignant Solid Neoplasm

27 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06311214·Phase 2·Recruiting

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Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyneuropathy

31 locations incl. Tucson

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18+

Code: NCT07032662·Phase 2·Recruiting

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MCC-24-GYN-11: Comparison of Nodal Sampling in Endometrial Cancer

for Endometrial Cancer

1 location in Lexington

Sponsor: Rachel Miller

Sex: Female·Age: 18+

Code: NCT06677112·Recruiting

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A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohns Disease

Drug: Afimkibart

92 locations incl. Dothan

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06819878·Phase 3·Recruiting

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Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

for Clear Cell Renal Cell Carcinoma

414 locations incl. Phoenix

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06661720·Phase 3·Recruiting

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Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

for Heart Failure

Drug: Dapagliflozin

194 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT06677060·Phase 3·Recruiting

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Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

for Fallopian Tube Endometrioid Adenocarcinoma

Drug: Bevacizumab

658 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06580314·Phase 3·Recruiting

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BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

for Limited Stage Small Cell Lung Cancer

Drug: Durvalumab

33 locations incl. Daphne

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 18+

Code: NCT06773910·Phase 2·Recruiting

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Transcranial Magnetic Stimulation for Methamphetamine Use Disorder in PLWH

for Methamphetamine Use Disorders

1 location in Lexington

Sponsor: Gopalkumar Rakesh

Sex: All·Age: 18 - 65

Code: NCT06830980·Recruiting

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A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines

for Psoriatic Arthritis

Drug: Zasocitinib

21 locations incl. Mesa

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06671496·Phase 3·Recruiting

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A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

for B-Cell Non-Hodgkins Lymphoma

Drug: Glofitamab

33 locations incl. Anchorage

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06806033·Phase 2·Recruiting

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Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment

for Non-small Cell Lung Cancer

Drug: Pumitamig

5 locations incl. Birmingham

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06841055·Phase 2·Recruiting

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A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

for HER2-positive Gastric Cancer

Drug: Rilvegostomig

53 locations incl. Anchorage

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06764875·Phase 3·Recruiting

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Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0

for Acute Kidney Injury

50 locations incl. Birmingham

Sponsor: Indiana University

Sex: All·Age: 0 Minutes - 2 Weeks

Code: NCT06823115·Enrolling By Invitation

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

for Advanced Solid Tumor

21 locations incl. Scottsdale

Sponsor: Clasp Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06778863·Phase 1·Recruiting

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Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

for Hidradenitis Suppurativa (HS)

Drug: Povorcitinib

108 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06855498·Phase 3·Recruiting

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Hydrocolloid Dressings for Oculofacial Plastic and Reconstructive Wound Healing

for Wound Healing

1 location in Lexington

Sponsor: Janice Hernandez, MD

Sex: All·Age: 18 - 100

Code: NCT07075159·Recruiting

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Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for Hematopoietic and Lymphatic System Neoplasm

190 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: Female·Age: Up to 39

Code: NCT06513962·Phase 3·Recruiting

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A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

for Immune Thrombocytopenic Purpura (ITP)

18 locations incl. Los Angeles

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06722235·Phase 3·Recruiting

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