Paid Clinical Trials in Kentucky

Kentucky has 1,052 paid clinical trials enrolling now across cities including Louisville, Lexington and Edgewood. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,052 clinical trials

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Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

for Non-Small Cell Lung Cancer

Drug: Ivonescimab

89 locations incl. Chandler

Sponsor: Summit Therapeutics

Sex: All·Age: 18+

Code: NCT06767514·Phase 3·Recruiting

Apply to this trial

A Phase 1 Study of IM-1021 in Participants With Advanced Cancer

for Solid Malignancies

12 locations incl. Duarte

Sponsor: Immunome, Inc.

Sex: All·Age: 18+

Code: NCT06823167·Phase 1·Recruiting

Apply to this trial

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

for Multiple System Atrophy

1 location in Lexington

Sponsor: Craig van Horne, MD, PhD

Sex: All·Age: 40 - 75

Code: NCT06683365·Phase 1·Recruiting

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Prevail Global Study

for Coronary Artery Disease

51 locations incl. Birmingham

Sponsor: Medtronic Vascular

Sex: All·Age: 18+

Code: NCT06535854·Recruiting

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A Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital Cytomegalovirus

for Congenital Cytomegalovirus Infection

10 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 0 Days - 90 Days

Code: NCT06118515·Phase 1·Recruiting

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Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease

for Degenerative Disc Disease

19 locations incl. Napa

Sponsor: VIVEX Biologics, Inc.

Sex: All·Age: 22 - 85

Code: NCT06778447·Recruiting

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Trauma-Informed Procedural Pain Intervention: Refinement of an Evidence-Based Protocol

for Procedural Pain

4 locations incl. Lexington

Sponsor: University of Louisville

Sex: All·Age: Up to 18

Code: NCT06705491·Recruiting

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Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

for Castration-Resistant Prostate Carcinoma

107 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06632977·Phase 2·Recruiting

Apply to this trial

A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

for Proteinuric Kidney Disease

Drug: MZE829

72 locations incl. Decatur

Sponsor: Maze Therapeutics

Sex: All·Age: 18 - 68

Code: NCT06830629·Phase 2·Recruiting

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Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

for Major Depressive Disorder

34 locations incl. Birmingham

Sponsor: Syndeio Biosciences, Inc

Sex: All·Age: 18 - 64

Code: NCT06547489·Phase 2·Recruiting

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EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

for Glioblastoma

32 locations incl. Phoenix

Sponsor: NovoCure GmbH

Sex: All·Age: 18+

Code: NCT06556563·Phase 3·Recruiting

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Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

for Extensive-stage Small-cell Lung Cancer

32 locations incl. Tucson

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06712355·Phase 3·Recruiting

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PT150 Drug for Use in Alcohol Use Disorder

for Alcohol Use Disorder

1 location in Lexington

Sponsor: Pop Test Oncology LLC

Sex: All·Age: 21 - 55

Code: NCT06712602·Phase 1·Recruiting

Apply to this trial

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

464 locations incl. Fairbanks

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting

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Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy

for Anaplastic Large Cell Lymphoma, ALK-Negative

158 locations incl. Birmingham

Sponsor: Eastern Cooperative Oncology Group

Sex: All·Age: 18 - 75

Code: NCT06724237·Phase 3·Recruiting

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FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

for Metastatic Head and Neck Squamous Cell Carcinoma

53 locations incl. Birmingham

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT06788990·Phase 2, Phase 3·Recruiting

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An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis

for Recurrent Pericarditis

Drug: VTX2735

17 locations incl. Tucson

Sponsor: Zomagen Biosciences Ltd.

Sex: All·Age: 18 - 75

Code: NCT06836232·Phase 2·Recruiting

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A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

for Diffuse Large B-Cell Lymphoma

Drug: Rituximab

42 locations incl. Gilbert

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06717347·Phase 3·Recruiting

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A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

for NonSegmental Vitiligo

Drug: Ruxolitinib

80 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 2 - 11

Code: NCT06548360·Phase 3·Recruiting

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DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

for Pulmonary Hypertension Due to Lung Diseases and Hypoxia

66 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT06388421·Recruiting

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A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

for Parkinson Disease

45 locations incl. Sun City

Sponsor: Neuron23 Inc.

Sex: All·Age: 40 - 80

Code: NCT06680830·Phase 2·Recruiting

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Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors

for Advanced Solid Tumor

7 locations incl. Louisville

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06750185·Phase 1·Recruiting

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A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)

for Type 2 Diabetes

Drug: Dulaglutide

41 locations incl. Tucson

Sponsor: Eli Lilly and Company

Sex: All·Age: 10 - 17

Code: NCT06739122·Phase 3·Recruiting

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A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

for Chickenpox

60 locations incl. Mobile

Sponsor: GlaxoSmithKline

Sex: All·Age: 12 Months - 15 Months·Accepts healthy volunteers

Code: NCT06740630·Phase 3·Recruiting

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Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

for Non-small Cell Lung Cancer

36 locations incl. Anchorage

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06712316·Phase 2, Phase 3·Recruiting

Apply to this trial

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

for Ovarian Cancer

14 locations incl. Newport Beach

Sponsor: NextCure, Inc.

Sex: All·Age: 18+

Code: NCT06774963·Phase 1·Recruiting

Apply to this trial

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

21 locations incl. Chandler

Sponsor: Loxo Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06588478·Phase 2·Recruiting

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A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

for Crohn's Disease

Drug: Upadacitinib

19 locations incl. La Jolla

Sponsor: Takeda

Sex: All·Age: 18 - 65

Code: NCT06227910·Phase 3·Recruiting

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Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

for Cutaneous Squamous Cell Carcinoma (CSCC)

Drug: Cemiplimab

45 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06585410·Phase 3·Recruiting

Apply to this trial

Genetic and Environmental Risk Factors for Hemorrhagic Stroke

for Stroke

7 locations incl. Chicago

Sponsor: State University of New York at Buffalo

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00682695·Recruiting

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Effectiveness and Safety of the RIGHTEST Continuous Glucose Monitoring System for Blood Glucose Management in Persons With Diabetes Mellitus

for Diabetes Mellitus

13 locations incl. Guntersville

Sponsor: Bionime Corporation

Sex: All·Age: 18+

Code: NCT04838392·Not Yet Recruiting

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

for Staphylococcus Aureus

Drug: AZD7760

43 locations incl. Huntsville

Sponsor: AstraZeneca

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT06749457·Phase 1, Phase 2·Recruiting

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A Study of ASP-1929 Photoimmunotherapy in Combination With Pembrolizumab in First-line Treatment of Locoregional Recurrent Squamous Cell Carcinoma of the Head and Neck With No Distant Metastases

for Recurrent Head and Neck Squamous Cell Carcinoma

8 locations incl. Duarte

Sponsor: Rakuten Medical, Inc.

Sex: All·Age: 18+

Code: NCT06699212·Phase 3·Recruiting

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A Multicenter Study to Evaluate Safety, Tolerability, and Clinical Responses of DSP-1083 Into Subjects With Parkinson's Disease

for Parkinson's Disease

2 locations incl. Lexington

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 40 - 72

Code: NCT06753331·Phase 1, Phase 2·Recruiting

Apply to this trial

Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy

for IgA Nephropathy

37 locations incl. Birmingham

Sponsor: Calliditas Therapeutics AB

Sex: All·Age: 18+

Code: NCT06712407·Phase 4·Recruiting

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A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

for Graves' Disease

Drug: IMVT-1402

64 locations incl. Phoenix

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 75

Code: NCT06727604·Phase 2·Recruiting

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Amiodarone-Infused CardiaMend Patches for the Prevention of New-Onset POAF in Cardiac Surgery Subjects

for Atrial Fibrillation, Postoperative

1 location in Louisville

Sponsor: Helios Cardio Inc.

Sex: All·Age: 20 - 85

Code: NCT06730828·Phase 1, Phase 2·Recruiting

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A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors

for Squamous Non-small-cell Lung Cancer

8 locations incl. Scottsdale

Sponsor: Alentis Therapeutics AG

Sex: All·Age: 18+

Code: NCT06747585·Phase 1, Phase 2·Recruiting

Apply to this trial

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for Heart Failure

57 locations incl. Phoenix

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06526195·Recruiting

Apply to this trial

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

for Anatomic Stage IV Breast Cancer AJCC v8

256 locations incl. Tucson

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500455·Phase 3·Recruiting

Apply to this trial