Paid Clinical Trials in Kentucky

Kentucky has 1,052 paid clinical trials enrolling now across cities including Louisville, Lexington and Edgewood. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,052 clinical trials

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A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

for Ulcerative Colitis

25 locations incl. Canoga Park

Sponsor: Spyre Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07012395·Phase 2·Recruiting

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Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

Drug: IMVT-1402

46 locations incl. Huntsville

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 80

Code: NCT07039916·Phase 3·Recruiting

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Small Cell Lung Cancer Community Engagement to Eliminate Research Discepancies

for Small-cell Lung Cancer

52 locations incl. Multiple Locations

Sponsor: Addario Lung Cancer Medical Institute

Sex: All·Age: 18+

Code: NCT06486428·Recruiting

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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Drug: Cemiplimab

386 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06616584·Phase 2, Phase 3·Recruiting

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A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

for Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer

Drug: zolbetuximab

36 locations incl. Birmingham

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT06901531·Phase 3·Recruiting

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Effects of Carnosine In Patients With Peripheral Arterial Disease Patients

for Peripheral Arterial Disease

3 locations incl. Louisville

Sponsor: Shahid Baba

Sex: All·Age: 40 - 80

Code: NCT06480760·Phase 1, Phase 2·Recruiting

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A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

for Heart Failure

Drug: Empagliflozin

105 locations incl. Mobile

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06935370·Phase 3·Recruiting

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Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation

for Delayed Graft Function

32 locations incl. Phoenix

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06830798·Phase 3·Recruiting

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A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

for Lower Extremity Acute Limb Ischemia

31 locations incl. Scottsdale

Sponsor: Penumbra Inc.

Sex: All·Age: 18+

Code: NCT06747117·Recruiting

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Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

129 locations incl. Tucson

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06672146·Phase 2·Recruiting

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Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis

22 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT06947993·Phase 2·Recruiting

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Tibulizumab Skin Healing and Inflammation Evaluation for Lasting Defense

for Hidradenitis Suppurativa (HS)

31 locations incl. Phoenix

Sponsor: Zura Bio Inc

Sex: All·Age: 18 - 70

Code: NCT06993610·Phase 2·Recruiting

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Adaptive Intervention Strategies for HIV PrEP Care in Rural People Who Inject Drugs

for HIV Prevention

4 locations incl. Barbourville

Sponsor: Hilary L Surratt, PhD

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06666309·Enrolling By Invitation

A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

for Atopic Dermatitis

22 locations incl. Fountain Valley

Sponsor: Apogee Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07003425·Phase 2·Recruiting

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A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)

for Carcinoma, Non-Small-Cell Lung

2 locations incl. Lexington

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06780085·Phase 2·Recruiting

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A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

for Prostate Cancer

50 locations incl. Phoenix

Sponsor: Merck Sharp & Dohme LLC

Sex: Male·Age: 18+

Code: NCT06925737·Phase 3·Recruiting

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A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohns Disease

Drug: Afimkibart

50 locations incl. Glendale

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06819891·Phase 3·Recruiting

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Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula

for Pancreatic Carcinoma

118 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06807437·Phase 3·Recruiting

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EXoPERT EMERALD Clinical Study

for Breast Cancer

9 locations incl. Long Beach

Sponsor: EXoPERT

Sex: All·Age: 45+·Accepts healthy volunteers

Code: NCT07186296·Recruiting

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Mirikizumab Real World Protocol

for Ulcerative Colitis

8 locations incl. Denver

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18+

Code: NCT06696014·Recruiting

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Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer

for Cervical Cancer

92 locations incl. Phoenix

Sponsor: Pfizer

Sex: Female·Age: 18+

Code: NCT06952660·Phase 4·Recruiting

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A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for Myelodysplastic Syndromes

23 locations incl. Duarte

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06499285·Phase 3·Recruiting

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Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis

for Myasthaenia Gravis

23 locations incl. Tucson

Sponsor: Cartesian Therapeutics

Sex: All·Age: 18+

Code: NCT06799247·Phase 3·Recruiting

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Treatment of Moderate to Severe Refractory Crohn's Disease

for Crohns Disease

13 locations incl. Scottsdale

Sponsor: Tr1X, Inc.

Sex: All·Age: 18 - 65

Code: NCT06721962·Phase 1, Phase 2·Recruiting

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WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

for Idiopathic Pulmonary Fibrosis

26 locations incl. Birmingham

Sponsor: Mediar Therapeutics

Sex: All·Age: 40+

Code: NCT06967805·Phase 2·Recruiting

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Osteopathic Manipulative Therapy Effects on Post-Acute Sequelae of COVID-19 (PASC) or Long COVID

for Long-COVID

1 location in Louisville

Sponsor: University of Louisville

Sex: All·Age: 18+

Code: NCT06883513·Recruiting

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Motiva Implants® Post-Approval Study

for Breast Implant

30 locations incl. Beverly Hills

Sponsor: Motiva USA LLC

Sex: Female·Age: 22+·Accepts healthy volunteers

Code: NCT06938399·Recruiting

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Lead-212 PSV359 Therapy for Patients With Solid Tumors

for Pancreatic Ductal Adenocarcinoma

8 locations incl. Miami

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT06710756·Phase 1, Phase 2·Recruiting

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A Study to Assess the Safety and Risk of Hypersensitivity Reactions of Sulbactam-durlobactam in Adults With Acinetobacter Baumannii-calcoaceticus (ABC) Complex Infection

for Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC)

10 locations incl. Gainesville

Sponsor: Innoviva Specialty Therapeutics

Sex: All·Age: 18+

Code: NCT06746883·Recruiting

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A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

for Carcinoma, Non-Small-Cell Lung

Drug: Adagrasib

54 locations incl. Birmingham

Sponsor: Mirati Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06875310·Phase 3·Recruiting

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InterTAN: Integrated Dual Screw Design Improve Biomechanics/Function Following Fixation Surgery

for Fracture of Hip

1 location in Lexington

Sponsor: Paul E. Matuszewski

Sex: All·Age: 55+

Code: NCT06024304·Recruiting

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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for Stage I Mixed Cell Type Kidney Wilms Tumor

146 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT06401330·Phase 3·Recruiting

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A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003)

for Ovarian Cancer Recurrent

8 locations incl. New Haven

Sponsor: Merck Sharp & Dohme LLC

Sex: Female·Age: 18+

Code: NCT06843447·Phase 1, Phase 2·Recruiting

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Registry on NeVa VS for CerebraL VAsospasm ManagemenT in Post SAH PatiEnts

for Cerebral Vasospasm

16 locations incl. Burbank

Sponsor: Vesalio

Sex: All·Age: 22+

Code: NCT06893588·Recruiting

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A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

for Lymphoma, Large B-Cell, Diffuse

Drug: Polatuzumab Vedotin

70 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06890884·Phase 2·Recruiting

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer

for Carcinoma, Non-Small Cell Lung

Drug: Rilvegostomig

37 locations incl. La Mesa

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06868277·Phase 3·Recruiting

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An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome

for Lennox Gastaut Syndrome

20 locations incl. Little Rock

Sponsor: Epygenix

Sex: All·Age: 2 - 55

Code: NCT05066217·Phase 3·Recruiting

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A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for Breast Cancer

51 locations incl. Phoenix

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06790693·Phase 3·Recruiting

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Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

for Extensive Stage Lung Small Cell Carcinoma

Drug: Atezolizumab

43 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06287775·Phase 1, Phase 2·Recruiting

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Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis

for Multiple Sclerosis, Relapsing-Remitting

12 locations incl. Loma Linda

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 10 - 17

Code: NCT06408259·Phase 3·Recruiting

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