Effects of Carnosine In Patients With Peripheral Arterial Disease Patients

Part of paid clinical trials in Louisville, Kentucky.

Sponsor
Shahid Baba
Study ID
NCT06480760
Phase
PHASE1/PHASE2
Status
Recruiting
Apply to this trial

Conditions

  • Peripheral Arterial Disease

Eligibility Criteria

Sex
ALL
Age
40 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • Carnosine — DRUG
    Food ingredient (supplement)

Study Details

The purpose of this study is to determine whether carnosine (a food ingredient found in chicken and red meat) supplementation (2 g) for 6 months in participants with non-claudication and claudication peripheral arterial disease (PAD) improves walking ability. Previous studies with heart failure patients have shown that carnosine supplementation increases walking capacity in these patients.

Key Dates

Start date
May 20, 2025
Status verified
May 2025
Primary completion
Oct 1, 2028
Completion
Oct 1, 2028

Study Design

Enrollment
144 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • No Intervention: Placebo
    Cellulose
  • Experimental: Carnosine
    Carnosine 2 g daily for 6 months

Primary Outcome Measure

Measure distance covered on six-minute walk test (6MWT) [ Time Frame: Baseline, 3 months, 6 months, 9 months ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
University of Louisville School of Medicine, Department of Medicine, Division of Environmental MedicineLouisvilleKentucky40202
Shahid Baba, PhD
[email protected]
502-296-7713
Amit Dwivedi, MD
[email protected]
502-583-8303
University Surgical Associates, 401 E. Chestnut St, Suite 710LouisvilleKentucky40202
Shahid Baba, PhD
[email protected]
502-296-7713
Amit Dwivedi, MD
[email protected]
502-583-8303
UofL Physicians - Vascular Surgery Associates, 201 Abraham Flexner Way, Suite 1004LouisvilleKentucky40202
Shahid Baba, PhD
[email protected]
502-296-7713
Amit Dwivedi, MD
[email protected]
502-583-8303

Find similar trials in Louisville, KY

By research site
University of Louisville School of Medicine, Department of Medicine, Division of Environmental Medicine· Louisville, KYUniversity Surgical Associates, 401 E. Chestnut St, Suite 710· Louisville, KYUofL Physicians - Vascular Surgery Associates, 201 Abraham Flexner Way, Suite 1004· Louisville, KY

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