Paid Clinical Trials in Iowa

Iowa has 822 paid clinical trials enrolling now across cities including Iowa City, Des Moines and West Des Moines. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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822 clinical trials

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The Effects of Footplate Stiffness on Foot Loading Within Carbon Fiber Custom Dynamic Orthoses

for Trauma Injury

1 location in Iowa City

Sponsor: Jason Wilken

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07312032·Recruiting

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NV PSR INSPIRE-A Pipeline™ Vantage Post Approval Study

for Intracranial Aneurysm

6 locations incl. Jacksonville

Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All·Age: 22+

Code: NCT06604884·Recruiting

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Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

for Miscellaneous Neoplasm, Nos

231 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07091617·Recruiting

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A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

for Clostridioides Difficile Associated Disease

135 locations incl. Athens

Sponsor: Pfizer

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07282665·Phase 3·Recruiting

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Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.

for GEP-NET

7 locations incl. Iowa City

Sponsor: RayzeBio, Inc.

Sex: All·Age: 18+

Code: NCT07165132·Phase 1·Recruiting

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Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 Years

for Fuchs Endothelial Corneal Dystrophy

14 locations incl. Atlanta

Sponsor: Case Western Reserve University

Sex: All·Age: 30 - 93

Code: NCT07217249·Enrolling By Invitation

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

for Gastrointestinal Neoplasms

35 locations incl. Phoenix

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07218926·Phase 3·Recruiting

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A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

for Locally Advanced Urothelial Carcinoma

148 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06524544·Phase 3·Recruiting

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Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

for Castration-Sensitive Prostate Carcinoma

Drug: Apalutamide

194 locations incl. Tucson

Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male·Age: 18+

Code: NCT06931340·Phase 3·Recruiting

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Creating Health Course Study for People With Rheumatological Conditions

for Rheumatoid Arthritis

1 location in Iowa City

Sponsor: Terry L. Wahls

Sex: All·Age: 18 - 100

Code: NCT07180537·Recruiting

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Investigating Mediodorsal Thalamus Representations Underlying Human Cognitive Flexibility

for Schizophrenia

1 location in Iowa City

Sponsor: Kai Hwang

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT07217652·Recruiting

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A Study to Assess the Safety and Efficacy of LB-P8 in Patients With PSC

for Primary Sclerosing Cholangitis (PSC)

7 locations incl. Sacramento

Sponsor: LISCure Biosciences

Sex: All·Age: 18 - 75

Code: NCT06699121·Phase 2·Recruiting

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A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

for Small-cell Lung Cancer

Drug: ZL-1310

28 locations incl. Aurora

Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All·Age: 18+

Code: NCT07218146·Phase 3·Recruiting

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Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

for Type 2 Diabetes

52 locations incl. Chandler

Sponsor: Sparrow Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07296484·Phase 2·Recruiting

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Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

for Muscle Invasive Bladder Urothelial Carcinoma

143 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07061964·Phase 2·Recruiting

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Mirena for the Treatment of Nonatypical Endometrial Hyperplasia for 6 Months

for Endometrial Hyperplasia

69 locations incl. Birmingham

Sponsor: Bayer

Sex: Female·Age: 18+

Code: NCT06904274·Phase 3·Recruiting

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A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)

for Bipolar Disorder

Drug: Brenipatide

20 locations incl. Orange

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07286175·Phase 2·Recruiting

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Zymfentra (Infliximab-dyyb) REal World Cohort STudy

for Ulcerative Colitis (UC)

9 locations incl. New Haven

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18+

Code: NCT07237516·Recruiting

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Genetic Risk Factor for Heat Stroke

for Carrier State

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 60

Code: NCT06847256·Recruiting

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Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

for Carcinoid Syndrome

17 locations incl. Gilbert

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT07087054·Phase 3·Recruiting

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Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW)

for Autosomal Dominant Polycystic Kidney Disease (ADPKD)

26 locations incl. Alabaster

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 65

Code: NCT07161037·Phase 2·Recruiting

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A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment

for Idiopathic Pulmonary Fibrosis

Drug: BI 765423

15 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 40+

Code: NCT07036523·Phase 2·Recruiting

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A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

for Systemic Lupus Erythematosus (With and Without Nephritis)

12 locations incl. Phoenix

Sponsor: Allogene Therapeutics

Sex: All·Age: 18 - 69

Code: NCT07085104·Phase 1·Recruiting

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A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

for Ovarian Cancer

Drug: INCB123667

42 locations incl. Mobile

Sponsor: Incyte Corporation

Sex: Female·Age: 18 - 99

Code: NCT07023627·Phase 2·Recruiting

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Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

for B-cell Acute Lymphoblastic Leukemia (B-ALL)

6 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT07109219·Phase 1, Phase 2·Recruiting

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Impact of Anatomy-Based Cochlear Implant Programming on Early Performance

for Hearing Loss, Unilateral

6 locations incl. Iowa City

Sponsor: Med-El Corporation

Sex: All·Age: 18+

Code: NCT06734039·Enrolling By Invitation

A Long-Term Study of Bivamelagon in Participants With Hypothalamic Obesity (HO)

for Hypothalamic Obesity

6 locations incl. Aurora

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 12+

Code: NCT07156578·Phase 2·Enrolling By Invitation

Ketorolac Use and Fresh Embryo Transfer Outcomes

for Infertility (IVF Patients)

1 location in Iowa City

Sponsor: Jessica D. Kresowik

Sex: Female·Age: 18 - 37

Code: NCT07185724·Phase 4·Recruiting

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A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial Fibrillation

for Atrial Fibrillation (AF)

32 locations incl. Birmingham

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07187115·Recruiting

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Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

148 locations incl. Loma Linda

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting

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Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa

Drug: Brivekimig

13 locations incl. Scottsdale

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07170917·Phase 2·Recruiting

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A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

for Non-muscle Invasive Bladder Cancer

39 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07206225·Phase 1·Recruiting

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Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

for Neovascular Age-related Macular Degeneration

Drug: Surabgene Lomparvovec

53 locations incl. Mesa

Sponsor: AbbVie

Sex: All·Age: 50+

Code: NCT07007065·Phase 3·Recruiting

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Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for Locally Advanced Cervical Adenocarcinoma

260 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07061977·Phase 3·Recruiting

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Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

for Breast Cancer

Drug: Palazestrant

28 locations incl. Hot Springs

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07085767·Phase 3·Recruiting

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Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

for Bladder Cancer

6 locations incl. Tampa

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT07225127·Recruiting

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The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage

for Cataract and IOL Surgery

1 location in West Des Moines

Sponsor: Matthew Rauen

Sex: All·Age: 60+

Code: NCT07223866·Not Yet Recruiting

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

Drug: Divarasib

50 locations incl. Anchorage

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06793215·Phase 3·Recruiting

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A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A

for Haemophilia A

5 locations incl. Aurora

Sponsor: Novo Nordisk A/S

Sex: Male·Age: 18 - 64·Accepts healthy volunteers

Code: NCT07220564·Phase 1·Recruiting

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Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

for Heart Failure - NYHA II - IV

32 locations incl. Huntsville

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07069738·Recruiting

Apply to this trial