Clinical Trials at University of South Carolina
As of June 2026, 26 paid clinical trials are recruiting at University of South Carolina, located at 1401 DEVINE ST, COLUMBIA, SC 29208-0001, phone (803) 777-3175 in Columbia, South Carolina. Active studies at this site cover conditions such as Heart Failure, Stroke and Narcolepsy Type 1. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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26 clinical trials at University of South Carolina
·Clear filters·↓ Download CSVImproving the HIV Care Continuum With mHealth Technology
Mindful Walking Neural Correlates of Executive Function in SC Older Adults at Risk of Dementias
Efficacy of Center-based Childcare to Mitigate Unhealthy Weight Gain in Preschoolers From Low-income Households During the Summer
Community Health Worker Coaching to Reduce Cardiovascular Risk Among Women After a Hypertensive Disorder of Pregnancy
Church Implementation of a Social Support Intervention to Increase Physical Activity in Older African American Adults
Evaluating the Auricular Point Acupressure-Self Management Program for Chronic Musculoskeletal Pain Among Rural Populations
Mobile Supportive Teams for Reinforcing Increased Daily Exercise Study
Evaluating the Feasibility and Preliminary Effects of BE+
MiREA-AC for Reducing Problematic Alcohol and Marijuana Use in College Students
Dose Response of Exercise for Arthritis Management
Increasing Affordable Fruits and Vegetables for Families With Food Insecurity
The LEADS Trial (Linking Exericise for Advancing Daily Stress Management)
Optimizing a Remote-based Physical Activity Intervention for Adults With Total Knee Replacement
Healthy Kids Beyond the Bell: Investigating the Impact of After-School and Summer Programs
Determining the Optimal Amount of Structured Environments for Healthy Kids
Optimal Digital Weight Loss Treatment for Rural Individuals
Beneficial or Fostering Future Struggles (B.F.F.s)? Characterizing the Role of Friends in the Development of 13- to 17-Year-Old Adolescents
Reducing Metabolic Dysregulation in Dyads
Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students
Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads
Effectiveness of a Cancer Exercise Program
Escitalopram and Language Intervention for Subacute Aphasia
Neural Bases of Vocal Sensorimotor Impairment in Aphasia
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
About research studies in Columbia
Columbia has approximately 171 recruiting research studies across a wide range of therapeutic areas. South Carolina hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Common conditions studied in Columbia
- Heart Failure (8 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Stroke (6 active studies). Stroke trials test acute reperfusion strategies, neuroprotective agents, and rehabilitation technologies to improve recovery.
- Narcolepsy Type 1 (5 active studies). Recruiting Narcolepsy Type 1 studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Narcolepsy Type 2 (5 active studies). Recruiting Narcolepsy Type 2 studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Myeloid Leukemia (4 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Aphasia (4 active studies). Recruiting Aphasia studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Columbia
- University of South Carolina
- Children's Oncology Group
- National Cancer Institute (NCI)
- AstraZeneca
- Alkermes, Inc.
Local regulations and guidelines
Clinical trials in South Carolina are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. South Carolina research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Columbia. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Columbia
Hipa.ai aggregates every recruiting study in Columbia from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Columbia?
There are approximately 171 recruiting clinical trials in Columbia, South Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Columbia pay participants?
Most recruiting trials in Columbia compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Columbia?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Columbia?
The most common conditions under active study in Columbia include Heart Failure (8), Stroke (6), Narcolepsy Type 1 (5), Narcolepsy Type 2 (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Columbia?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Columbia on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Columbia?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Columbia?
Recruiting research sites in Columbia include Prisma Health Richland Hospital, University of South Carolina, Prisma Health, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Columbia right now?
The largest active categories in Columbia are Cancer & tumors (26), Cardiovascular (20), Diabetes & metabolic (17). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of University of South Carolina?
University of South Carolina is located at 1401 DEVINE ST, COLUMBIA, SC 29208-0001. Use the Google Maps link in the intro above to get directions.
How do I contact University of South Carolina?
You can reach University of South Carolina by phone at (803) 777-3175. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.