As of June 2026, 171 paid clinical trials are recruiting in Columbia, South Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Columbia offers studies at sites including Prisma Health Richland Hospital for conditions such as Heart Failure, Stroke, Narcolepsy Type 1, Narcolepsy Type 2. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Columbia has approximately 171 recruiting research studies across a wide range of therapeutic areas. South Carolina hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Researchers run research studies in Columbia, SC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Prisma Health Richland Hospital | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm | 37 |
| University of South Carolina | Physical Activity, Aphasia, Health Status Disparities | 26 |
| Prisma Health | Amblyopia, AHRF, ARDS (Moderate or Severe) | 6 |
| Bogan Sleep Consultants, LLC | Idiopathic Pulmonary Fibrosis (IPF), Narcolepsy, Narcolepsy Type 1 | 4 |
| Prisma Health Children's Hospital - Midlands | Idiopathic Short Stature, Cystic Fibrosis, Hypogonadism, Male | 4 |
| Prisma Health Midlands | Cardiovascular Diseases, Heart Diseases, Heart Failure | 4 |
| Columbia Dermatology & Aesthetics | Hidradenitis Suppurativa, Overweight or Obesity, Psoriasis | 4 |
| Alkermes Investigational Site | Narcolepsy Type 1, Narcolepsy Type 2, Idiopathic Hypersomnia | 3 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| Ascendis Investigational Site | Growth Hormone Deficiency | 2 |
| Columbia Digestive Health Research | Celiac Disease, Metabolic Dysfunction-Associated Steatotic Liver Disease | 2 |
| Columbia, South Carolina | Narcolepsy Type 1, Narcolepsy Type 2, Idiopathic Hypersomnia | 2 |
| Medical University of South Carolina | Atrial Fibrillation, Congenital Heart Disease (CHD) | 2 |
| ObjectiveHealth-Columbia Digestive Health Research | Liver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis, Metabolic Dysfunction Associated Steatohepatitis (MASH) | 2 |
| Prisma Health - Midlands | Heart Failure, Open tíbia Fracture | 2 |
| Prisma Health Richland | Hypertensive Disorder, Lexical Access in Neurotypicals | 2 |
| Vanda Investigational Site | Chronobiology Disorders, Insomnia Disorder, Sleep Disorders, Circadian Rhythm | 2 |
| Wm. Jennings Bryan Dorn VA Medical Center, Columbia, SC | Atherosclerosis, Carcinoma, Hepatocellular, Cirrhosis | 2 |
| Takeda | Idiopathic Hypersomnia, Narcolepsy Type 1 (NT1), Narcolepsy With Cataplexy | 2 |
| Velocity Clinical Research - Columbia | COPD, Dermatitis Atopic | 2 |
| Alkermes Investigator Site | Idiopathic Hypersomnia | 1 |
| Arnold School of Public Health | Mild-moderate Cognitive Impairment | 1 |
| Blatt PE Center, University of South Carolina | Lower Extremity Muscular Power Performance Output | 1 |
| Bogan Sleep Consultants | Obesity, Overweight, Sleep Apnea, Obstructive | 1 |
Recruiting trials in Columbia grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Clinical trials in South Carolina are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. South Carolina research additionally follows state public health department oversight and any applicable state privacy statutes.
Hipa.ai aggregates every recruiting study in Columbia from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
There are approximately 171 recruiting clinical trials in Columbia, South Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Columbia compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Columbia include Heart Failure (8), Stroke (6), Narcolepsy Type 1 (5), Narcolepsy Type 2 (5), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Columbia on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Columbia include Prisma Health Richland Hospital, University of South Carolina, Prisma Health, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Columbia are Cancer & tumors (26), Cardiovascular (20), Diabetes & metabolic (17). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.