Clinical Trials at Cincinnati Children's Hospital Medical Center

As of June 2026, 295 paid clinical trials are recruiting at Cincinnati Children's Hospital Medical Center, located at 3333 BURNET AVENUE, 11027, CINCINNATI, OH 45229, phone (513) 803-4738 in Cincinnati, Ohio. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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295 clinical trials at Cincinnati Children's Hospital Medical Center

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Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry

for Turner Syndrome

10 locations incl. Aurora

Sponsor: University of Colorado, Denver

Sex: Female·Age: All ages

Code: NCT05052606·Recruiting

Apply to this trial

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

for Malignancy

626 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: All ages

Code: NCT04242095·Recruiting

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A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for Low Grade Astrocytoma

Drug: Selumetinib

124 locations incl. Aurora

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 - 21

Code: NCT04166409·Phase 3·Recruiting

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Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation

for Sickle Cell Disease

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT04093986·Recruiting

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

203 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting

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Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy

for Inflammatory Bowel Diseases

3 locations incl. Hartford

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 11 - 25

Code: NCT03847467·Phase 1, Phase 2·Recruiting

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Improving Outcomes in Pediatric Obstructive Sleep Apnea With Computational Fluid Dynamics

for Obstructive Sleep Apnea

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 3 - 18

Code: NCT04991389·Phase 4·Recruiting

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Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

for Lower Respiratory Tract Infection

49 locations incl. Duarte

Sponsor: Ansun Biopharma, Inc.

Sex: All·Age: All ages

Code: NCT03808922·Phase 3·Recruiting

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Stroke Prevention With Hydroxyurea Enabled Through Research and Education (SPHERE)

for Sickle Cell Anemia in Children

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 2 - 16

Code: NCT03948867·Phase 2·Enrolling By Invitation

Stress Hydrocortisone In Pediatric Septic Shock

for Septic Shock

18 locations incl. Tucson

Sponsor: Jerry Zimmerman

Sex: All·Age: 1 Month - 17

Code: NCT03401398·Phase 3·Recruiting

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Studying Health Outcomes After Treatment in Patients With Retinoblastoma

for Retinoblastoma

10 locations incl. Chicago

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT03932786·Recruiting

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Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

for Infant, Extremely Premature

37 locations incl. Birmingham

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 0 - 1

Code: NCT05685745·Recruiting

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Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia

for Leukemia

Drug: Venetoclax

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 1 - 39

Code: NCT03826992·Phase 1·Recruiting

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Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

for Pulmonary Invasive Fungal Infections

32 locations incl. Little Rock

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: 120 Days - 21

Code: NCT03827694·Recruiting

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Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

for Ewing Sarcoma

23 locations incl. Scottsdale

Sponsor: Inhibrx Biosciences, Inc

Sex: All·Age: 12 - 85

Code: NCT03715933·Phase 1·Recruiting

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Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

for Spinal Muscular Atrophy (SMA)

50 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: All ages

Code: NCT04174157·Recruiting

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Markers of Trajectory in Pediatric CRPS

for Complex Regional Pain Syndromes

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 10 - 17·Accepts healthy volunteers

Code: NCT03838107·Recruiting

Apply to this trial

Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric AKI

for Acute Kidney Injury

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 3 Months - 25

Code: NCT03541785·Enrolling By Invitation

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

152 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting

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Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD

for ADHD

4 locations incl. Gainesville

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 6 - 17

Code: NCT03781752·Phase 4·Recruiting

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Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

for Severe Combined Immunodeficiency, X Linked

4 locations incl. Los Angeles

Sponsor: David Williams

Sex: Male·Age: 0 - 5

Code: NCT03311503·Phase 1, Phase 2·Recruiting

Apply to this trial

RASopathy Biorepository

for RAS Mutation

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04395495·Recruiting

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Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

for Recurrent B Acute Lymphoblastic Leukemia

156 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 21

Code: NCT02981628·Phase 2·Recruiting

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Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

for Childhood Extracranial Germ Cell Tumor

566 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT03067181·Phase 3·Recruiting

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Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection

for Chronic Hepatitis B

22 locations incl. Los Angeles

Sponsor: Gilead Sciences

Sex: All·Age: 2 - 17

Code: NCT02932150·Phase 2·Recruiting

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The Congenital Dyserythropoietic Anemia Registry (CDAR)

for Congenital Dyserythropoietic Anemia (CDA)

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT02964494·Recruiting

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Quality of Pediatric Resuscitation in a Multicenter Collaborative

for Cardiac Arrest

40 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 - 18

Code: NCT02708134·Recruiting

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TSC Biosample Repository and Natural History Database

for Tuberous Sclerosis

24 locations incl. Birmingham

Sponsor: National Tuberous Sclerosis Association

Sex: All·Age: All ages

Code: NCT05676099·Recruiting

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Shwachman Diamond Syndrome Registry and Study

for Shwachman-Diamond Syndrome

4 locations incl. Aurora

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT06056908·Recruiting

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

245 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting

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CAR-T Long Term Follow Up (LTFU) Study

for Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program

44 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 0 - 100

Code: NCT02445222·Phase 3·Recruiting

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Third Party Viral Specific T-cells (VSTs)

for Viral Infection

4 locations incl. Akron

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 2 Days+

Code: NCT02532452·Phase 2·Recruiting

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Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

75 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting

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OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages

for Eosinophilic Gastrointestinal Disorders (EGIDs)

19 locations incl. Phoenix

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 3+

Code: NCT02523118·Recruiting

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Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations

for PTEN

5 locations incl. Los Angeles

Sponsor: Boston Children's Hospital

Sex: All·Age: 18 Months+·Accepts healthy volunteers

Code: NCT02461446·Recruiting

Apply to this trial

A National Registry For Pulmonary Alveolar Proteinosis

for Pulmonary Alveolar Proteinosis

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT02461615·Recruiting

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Identification of Biomarkers for Patients with Vascular Anomalies

for Vascular Anomaly

2 locations incl. Boston

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 1 Day+

Code: NCT03001180·Recruiting

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Simple Bone Cysts in Kids

for Bone Cyst

11 locations incl. Birmingham

Sponsor: The Hospital for Sick Children

Sex: All·Age: 2 - 21

Code: NCT02193841·Phase 3·Recruiting

Apply to this trial

Use of Hyperpolarized 129Xe MR Lung Imaging in Adults for Calibration

for Respiratory Disorders

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT02316379·Phase 1, Phase 2·Recruiting

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Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults

for Respiratory Disorders

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 6+·Accepts healthy volunteers

Code: NCT02272049·Phase 1, Phase 2·Recruiting

Apply to this trial