Clinical Trials at Northwestern University

As of June 2026, 381 paid clinical trials are recruiting at Northwestern University, located at 303 E CHICAGO AVE, TARRY BUILDING, 11-703, CHICAGO, IL 60611-3008, phone (312) 503-0830 in Chicago, Illinois. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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381 clinical trials at Northwestern University

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Pemetrexed Response in Relation to Tumor Alterations of Gene Status for the Treatment of Patients With Metastatic Urothelial Bladder Cancer and Other Solid Tumors

for Metastatic Bladder Urothelial Carcinoma

2 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06630416·Phase 2·Recruiting

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Evaluation of the Safety and Effectiveness of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus

for Normal Pressure Hydrocephalus

28 locations incl. Los Angeles

Sponsor: CereVasc Inc

Sex: All·Age: 60+

Code: NCT06498960·Recruiting

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A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

for Gastroesophageal-junction Cancer

29 locations incl. Anaheim

Sponsor: Shanghai Henlius Biotech

Sex: All·Age: 18+

Code: NCT06532006·Phase 3·Recruiting

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

248 locations incl. Jonesboro

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting

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The SEQUENCE Trial: Evaluating Diagnostic Yield of Robotic-assisted Bronchoscopy When Staging EBUS is Performed First or Second in the Same Procedure

for Pulmonary Nodules

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06676956·Recruiting

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Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

for Heart Failure

6 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT06517186·Recruiting

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Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial

for Obstetrical Complications

14 locations incl. Birmingham

Sponsor: The George Washington University Biostatistics Center

Sex: Female·Age: All ages·Accepts healthy volunteers

Code: NCT06605118·Phase 3·Recruiting

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Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

for Scleroderma, Diffuse

14 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT06655896·Phase 2·Recruiting

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Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

for Cardiovascular Diseases

37 locations incl. Little Rock

Sponsor: BrioHealth Solutions, Inc.

Sex: All·Age: 18 - 100

Code: NCT06310031·Recruiting

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Reducing Disparities in Urinary Control Symptoms for Minority Women

for Urinary Incontinence (UI)

2 locations incl. Chicago

Sponsor: University of Chicago

Sex: Female·Age: 18+

Code: NCT06798311·Recruiting

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Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia

for Hypertension, Pregnancy-Induced

2 locations incl. Chicago

Sponsor: Medical College of Wisconsin

Sex: Female·Age: 18+

Code: NCT06220721·Recruiting

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Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

for Hypertensive Disorders of Pregnancy

16 locations incl. Birmingham

Sponsor: Ohio State University

Sex: Female·Age: 14 - 35

Code: NCT06468202·Phase 4·Recruiting

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Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06401577·Recruiting

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A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

for Ulcerative Colitis

46 locations incl. Chandler

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT06598943·Phase 2·Recruiting

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Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

for Breast Atypical Ductal Hyperplasia

11 locations incl. Tucson

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18 - 55

Code: NCT06184750·Phase 2·Recruiting

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Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

221 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06317649·Phase 2·Recruiting

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Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

211 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT05554406·Phase 2·Recruiting

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Duration of Ureteral Rest Prior to Ureteral Reconstruction Surgery

for Ureteral Stricture

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06384079·Recruiting

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XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma

for Metastatic Leiomyosarcoma

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06571734·Phase 2·Recruiting

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A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

68 locations incl. Birmingham

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting

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Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

for Non Small Cell Lung Cancer

Drug: Osimertinib

146 locations incl. Birmingham

Sponsor: PrECOG, LLC.

Sex: All·Age: 18+

Code: NCT06538038·Recruiting

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Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

167 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT05554393·Phase 2·Recruiting

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Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial

for Prostate Adenocarcinoma

5 locations incl. Los Angeles

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT06022822·Phase 2·Recruiting

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Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

for Metastatic Dedifferentiated Liposarcoma

245 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06422806·Phase 3·Recruiting

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Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial

for Prostate Adenocarcinoma

Drug: Relugolix

1 location in Chicago

Sponsor: Sean Sachdev

Sex: Male·Age: 18+

Code: NCT06499870·Phase 2·Recruiting

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EAT: A Reliable Eating Assessment Technology for Free-living Individuals

for Wearable Electronic Device

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06118528·Recruiting

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A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)

for Lupus Erythematosus, Systemic

19 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06581198·Phase 2·Recruiting

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Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers

for Huntington Disease

13 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 25 - 60

Code: NCT06667414·Recruiting

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Evolution of the Chicago Classification: Bridging Physiology and Mechanics

for Dysphagia

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 85

Code: NCT06883175·Recruiting

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EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

for Kidney Disease, Chronic

Drug: Empagliflozin

41 locations incl. Huntsville

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06531824·Phase 3·Recruiting

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Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

for Breast Atypical Hyperplasia

4 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 35+

Code: NCT05941520·Phase 2·Recruiting

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Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

for Refractory Differentiated Thyroid Gland Carcinoma

301 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT06475989·Phase 3·Recruiting

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Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke

for Chronic Hemiparetic Stroke

2 locations incl. Chicago

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 80

Code: NCT06400186·Recruiting

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EFS of the DUO System for Tricuspid Regurgitation

for Tricuspid Regurgitation

12 locations incl. Phoenix

Sponsor: CroiValve Limited

Sex: All·Age: 18+

Code: NCT05913908·Recruiting

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An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

for Hematologic Malignancy

Drug: Pelabresib

6 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06401356·Phase 3·Recruiting

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ENhancing Exercise With LIGHT to Improve Functioning in PAD

for Peripheral Artery Disease

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 50+

Code: NCT06399900·Recruiting

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

266 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18 Minutes+

Code: NCT06031688·Phase 2·Recruiting

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A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

13 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06313593·Phase 1·Recruiting

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NOrthwestern Tempus AI-enaBLed Electrocardiography (NOTABLE) Trial

for Atrial Fibrillation

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 40+

Code: NCT06511505·Not Yet Recruiting

Segmentectomy After Induction Therapy (SAINT)

for Segmentectomy

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 89

Code: NCT06496659·Recruiting

Apply to this trial