Clinical Trials at McLean Hospital
As of June 2026, 36 paid clinical trials are recruiting at McLean Hospital, located at 115 MILL ST, BELMONT, MA 02478-1041, phone (617) 855-3311 in Belmont, Massachusetts. Active studies at this site cover conditions such as Schizophrenia, Psychosis and Schizoaffective Disorder. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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36 clinical trials at McLean Hospital
·Clear filters·↓ Download CSVA Pilot Trial of One-Day Accelerated TMS and D-cycloserine in Suicidal Patients With Borderline Personality Disorder
Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis
An Intervention to Reduce Discrepancy in Everyday Preferences
Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression
A Study of Brenipatide in Adult Participants With Schizophrenia
Identifying Substance Use Consequences
Stress Dynamics and Familial Risk for Depression in Female Adolescents
Pharmacologic Augmentation of TMS for Depression With D-serine
Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation
Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Open Label Extension Study of NCT06221852
Cerebellar Modulation of Cognition in Psychosis
PAIN: A Project Assessing the Impact of a Novel Cannabinoid Product
MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction
Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder
Evaluating the Impact of a Novel Cannabinoid Product for Endometriosis
Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder
Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan
Cerebellar TMS and Satiety in Prader-Willi Syndrome
Role of Parent Interpretation Bias in the Transmission of Anxiety to Children
Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder
Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services
Individually Targeted Neuromodulation for Contamination-based OCD
Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside
Interpretation Bias as a Mechanism of Treatment Response in OCD
Beyond Monoamines: The Role of the Nociceptin/Orphanin FQ Receptor in Major Depression
Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents
Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia
Neural Correlates of Stress and Perceived Control in Adolescent Depression
Early Life Stress and Depression: Molecular and Functional Imaging
Electroconvulsive Therapy (ECT) for Agitation in Dementia (AD)
Neurobiology of Posttraumatic Stress Disorder Dysfunction and Recovery Following Cognitive Processing Therapy
Evaluating the Neurobiological Basis of Traumatic Dissociation in Women With Histories of Abuse and Neglect
About research studies in Belmont
Belmont has approximately 44 recruiting research studies across a wide range of therapeutic areas. Massachusetts is a global epicenter of biomedical research, anchored by Harvard-affiliated hospitals (MGH, Brigham and Women's, Dana-Farber), Boston Children's Hospital, and the Kendall Square biotech corridor in Cambridge.
Common conditions studied in Belmont
- Schizophrenia (7 active studies). Schizophrenia research tests muscarinic agonists, long-acting injectable antipsychotics, and cognitive remediation therapies.
- Psychosis (5 active studies). Recruiting Psychosis studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Schizoaffective Disorder (5 active studies). Recruiting Schizoaffective Disorder studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Bipolar Disorder (3 active studies). Bipolar disorder studies explore mood stabilizers, novel adjunctive agents, and digital monitoring tools to reduce relapse.
- Bipolar I Disorder (3 active studies). Recruiting Bipolar I Disorder studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Cognitive Impairment (3 active studies). ENT (otolaryngology) trials evaluate new treatments for hearing loss, swallowing disorders, and head and neck cancers — covering pharmacologic, surgical, and rehabilitative approaches.
Leading research sponsors in Belmont
- Mclean Hospital
- Brigham and Women's Hospital
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Alto Neuroscience
- Beth Israel Deaconess Medical Center
Local regulations and guidelines
Clinical trials in Massachusetts are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Massachusetts trials follow additional state privacy requirements enforced under 201 CMR 17.00 and oversight from the Massachusetts Department of Public Health.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Belmont. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Belmont
Hipa.ai aggregates every recruiting study in Belmont from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Belmont?
There are approximately 44 recruiting clinical trials in Belmont, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Belmont pay participants?
Most recruiting trials in Belmont compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Belmont?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Belmont?
The most common conditions under active study in Belmont include Schizophrenia (7), Psychosis (5), Schizoaffective Disorder (5), Bipolar Disorder (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Belmont?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Belmont on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Belmont?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Belmont?
Recruiting research sites in Belmont include McLean Hospital, Harvard Mclean Hospital, Local Institution - 0008, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Belmont right now?
The largest active categories in Belmont are Mental health & behavior (23), Neurology & pain (4), Diabetes & metabolic (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of McLean Hospital?
McLean Hospital is located at 115 MILL ST, BELMONT, MA 02478-1041. Use the Google Maps link in the intro above to get directions.
How do I contact McLean Hospital?
You can reach McLean Hospital by phone at (617) 855-3311. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.