Individually Targeted Neuromodulation for Contamination-based OCD

Part of paid clinical trials in Belmont, Massachusetts.

Sponsor
Mclean Hospital
Study ID
NCT05048251
Status
Recruiting
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Conditions

  • Obsessive-Compulsive Disorder

Eligibility Criteria

Sex
ALL
Age
18 Years - 55 Years
Healthy Volunteers
Not accepted

Interventions

  • cTBS — DEVICE
    continuous theta burst stimulation
  • iTBS — DEVICE
    intermittent theta burst stimulation
  • sham — DEVICE
    sham stimulation

Study Details

Patients with obsessive-compulsive disorder (OCD) experience a wide array of different types of obsessions and compulsions. However, current treatments for OCD employ a "one size fits all" approach and are used for all patients regardless of symptom type. In this project, the investigators propose to investigate whether a novel method of transcranial magnetic stimulation specifically reduces contamination/washing symptoms - one of the most common types of OCD.

Key Dates

Start date
Jul 1, 2022
Status verified
Mar 2024
Primary completion
Jun 30, 2024
Completion
Jun 30, 2024

Study Design

Enrollment
50 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: cTBS
    continuous TBS to right MFG
  • Experimental: iTBS
    intermittent TBS to right MFG
  • Sham Comparator: sham
    sham stimulation to right MFG

Primary Outcome Measure

Functional connectivity between R MFG and brain regions within VAN (expressed as a Z-score) [ Time Frame: 6 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
McLean HospitalBelmontMassachusetts02478
Brian P Brennan, MD
[email protected]
617-855-2911

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By research site
McLean Hospital· Belmont, MA

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